Human PTP beta / zeta /PTPRZ Antibody

Catalog # Availability Size / Price Qty
PTP beta / zeta /PTPRZ in Human Brain.
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Product Details
Citations (1)
Supplemental Products
Reviews (1)

Human PTP beta / zeta /PTPRZ Antibody Summary

Species Reactivity
Detects human PTP beta / zeta /PTPRZ in direct ELISAs.
Monoclonal Rat IgG2A Clone # 279245
Protein A or G purified from hybridoma culture supernatant
E. coli-derived recombinant human PTP beta / zeta /PTPRZ
Accession # P23471
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
8-25 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunohistochemistry PTP beta /?/PTPRZ antibody in Human Brain by Immunohistochemistry (IHC-P). View Larger

PTP beta / zeta /PTPRZ in Human Brain. PTP beta /zeta/PTPRZ was detected in immersion fixed paraffin-embedded sections of human brain (cortex) using Rat Anti-Human PTP beta /zeta/PTPRZ Monoclonal Antibody (Catalog # MAB26881) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Rat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS017) and counterstained with hematoxylin (blue). Specific staining was localized to neuronal cell bodies. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Preparation and Storage

Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: PTP beta/zeta/PTPRZ

PTPRZ, also known as Protein tyrosine phosphatase beta/zeta (PTP beta / zeta ), is a member of the receptor-type protein-tyrosine phosphatase family. This phosphatase is involved in the regulation of specific developmental processes in the central nervous system. A protein of 2,307 amino acids, PTPRZ is membrane-spanning with two cytoplasmic protein tyrosine phosphatase domains and an extracellular domain.

Long Name
Protein Tyrosine Phosphatase beta/zeta
Entrez Gene IDs
5803 (Human)
Alternate Names
3F8 CSPG ; HPTPZ; phosphacan; protein tyrosine phosphatase, receptor-type, Z polypeptide 1; PTP beta/zeta; PTP18; PTPRZ; PTPRZ1; PTPZ; receptor-type, zeta polypeptide 1; RPTPB; RPTPbeta

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Citation for Human PTP beta / zeta /PTPRZ Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth
    Authors: Y Shi, YF Ping, W Zhou, ZC He, C Chen, BS Bian, L Zhang, L Chen, X Lan, XC Zhang, K Zhou, Q Liu, H Long, TW Fu, XN Zhang, MF Cao, Z Huang, X Fang, X Wang, H Feng, XH Yao, SC Yu, YH Cui, X Zhang, JN Rich, S Bao, XW Bian
    Nat Commun, 2017;8(0):15080.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry


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Isotype Controls

Reconstitution Buffers

Secondary Antibodies

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Human PTP beta / zeta /PTPRZ Antibody
By Anonymous on 02/01/2022
Application: IHC Sample Tested: Brain tissue Species: Human