Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Flow Cytometry, Functional Assay

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Monoclonal Rat IgG2A Clone # 279245
View all PTP beta/zeta/PTPRZ Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human PTP beta / zeta /PTPRZ
Gly302-Asn754
Accession # P23471

Specificity

Detects human PTP beta / zeta /PTPRZ in direct ELISAs.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for PTP beta/zeta/PTPRZ Antibody (279245) [FITC]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional Assay

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Spectra Viewer

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: PTP beta/zeta/PTPRZ

PTPRB is a member of the protein tyrosine phosphatase (PTP) family. The family comprises at least 37 proteins, characterized by a catalytic phosphatase domain of approximately 240 amino acids, and includes both transmembrane and cytosolic enzymes. PTP1B is a transmembrane PTP. The PTPs have high substrate specificity for phosphotyrosyl proteins, at the primary sequence level sharing little similarity with the protein serine phosphatases, protein threonine phosphatases, or the acid and alkaline phosphatases. PTP beta interacts with and regulates the tyrosine phosphorylation level of catenins, which are critical in physiological and pathological events such as cell migration, adhesion and transformation.

Long Name

Protein Tyrosine Phosphatase beta/zeta

Alternate Names

HPTPZ, PTP18, PTPRZ, PTPRZ1, RPTPB

Gene Symbol

PTPRZ1

Additional PTP beta/zeta/PTPRZ Products

Product Documents for PTP beta/zeta/PTPRZ Antibody (279245) [FITC]

Certificate of Analysis

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Product Specific Notices for PTP beta/zeta/PTPRZ Antibody (279245) [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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