Rat IgG2A Isotype Control Summary
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Example

Detection of Rat IgGControl by Flow Cytometry
B16-F1 mouse melanoma cell line was stained with RatAnti-Mouse Integrin beta 1/CD29 Monoclonal Antibody (Catalog # MAB2405,filled histogram) or Rat IgG Isotype Control Antibody (Catalog #MAB006,open histogram), followed by Phycoerythrin-conjugated Anti-Rat IgG SecondaryAntibody
(Catalog # F0105B).
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: IgG2A
R&D Systems offers a range of secondary antibodies and controls for flow cytometry, immunohistochemistry, and Western blotting. We provide species-specific secondary antibodies that are available with a variety of conjugated labels.
Our NorthernLights fluorescent secondary antibodies are bright and resistant to photobleaching. We are currently offering secondary antibodies recognizing mouse, rat, goat, sheep, and rabbit IgG as well as chicken IgY. These reagents are available with three distinct excitation and emission maxima, making them ideal for multi-color fluorescence microscopy.
Product Datasheets
Citations for Rat IgG2A Isotype Control
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
101
Citations: Showing 1 - 10
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Regulation of T(H)2 development by CXCR5+ dendritic cells and lymphotoxin-expressing B cells.
Authors: Leon B, Ballesteros-Tato A, Browning JL, Dunn R, Randall TD, Lund FE
Nat. Immunol., 2102;13(7):681-90.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
Therapeutic potential of tranilast for the treatment of chronic graft-versus-host disease in mice
Authors: S Mukai, Y Ogawa, H Saya, Y Kawakami, K Tsubota
PLoS ONE, 2018;13(10):e0203742.
Species: Mouse
Sample Types: Whole Tissue
Applications: Isotype control -
Estrogen Deficiency Promotes Cerebral Aneurysm Rupture by Upregulation of Th17 Cells and Interleukin-17A Which Downregulates E-Cadherin
Authors: BL Hoh, K Rojas, L Lin, HZ Fazal, S Hourani, KW Nowicki, MB Schneider, K Hosaka
J Am Heart Assoc, 2018;7(8):.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo -
Regulatory T cells promote myelin regeneration in the central nervous system
Authors: Y Dombrowski, T O'Hagan, M Dittmer, R Penalva, SR Mayoral, P Bankhead, S Fleville, G Eleftheria, C Zhao, M Naughton, R Hassan, J Moffat, J Falconer, A Boyd, P Hamilton, IV Allen, A Kissenpfen, PN Moynagh, E Evergren, B Perbal, AC Williams, RJ Ingram, JR Chan, RJ Franklin, DC Fitzgerald
Nat. Neurosci, 2017;0(0):.
Species: Mouse
Sample Types: Whole Tissue
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MiR-497?195 cluster regulates angiogenesis during coupling with osteogenesis by maintaining endothelial Notch and HIF-1? activity
Authors: M Yang, CJ Li, X Sun, Q Guo, Y Xiao, T Su, ML Tu, H Peng, Q Lu, Q Liu, HB He, TJ Jiang, MX Lei, M Wan, X Cao, XH Luo
Nat Commun, 2017;8(0):16003.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Elucidation of the Role of Lectin-Like oxLDL Receptor-1 in the Metabolic Responses of Macrophages to Human oxLDL
Authors: DW Kimmel, WP Dole, DE Cliffel
J Lipids, 2017;2017(0):8479482.
Species: Mouse
Sample Types: Whole Cells
Applications: Neut -
FGF23 expression in rodents is directly induced via erythropoietin after inhibition of hypoxia inducible factor proline hydroxylase
Authors: I Flamme, P Ellinghaus, D Urrego, T Krüger
PLoS ONE, 2017;12(10):e0186979.
Species: Rat
Sample Types: In Vivo
Applications: Ctrl -
Microbiome-mediated neutrophil recruitment via CXCR2 and protection from amebic colitis
Authors: K Watanabe, CA Gilchrist, MJ Uddin, SL Burgess, MM Abhyankar, SN Moonah, Z Noor, JR Donowitz, BN Schneider, T Arju, E Ahmed, M Kabir, M Alam, R Haque, P Pramoonjag, B Mehrad, WA Petri
PLoS Pathog., 2017;13(8):e1006513.
Species: Mouse
Sample Types: In Vivo
Applications: Neut -
PD-1 Blockade Promotes Emerging Checkpoint Inhibitors in Enhancing T Cell Responses to Allogeneic Dendritic Cells
Authors: C Stecher, C Battin, J Leitner, M Zettl, K Grabmeier-, C Höller, GJ Zlabinger, P Steinberge
Front Immunol, 2017;8(0):572.
Species: Human
Sample Types: Whole Cells
Applications: Ctrl -
Evaluation of F8-TNF-? in Models of Early and Progressive Metastatic Osteosarcoma
Authors: B Robl, SM Botter, A Boro, D Meier, D Neri, B Fuchs
Transl Oncol, 2017;10(3):419-430.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC OCT-embedded -
Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Displacement of TLR9
Authors: JA Schwartz, KL Clayton, S Mujib, H Zhang, AK Rahman, J Liu, FY Yue, E Benko, C Kovacs, MA Ostrowski
J. Immunol, 2017;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neut -
Role of Eosinophils and Tumor Necrosis Factor Alpha in Interleukin-25-Mediated Protection from Amebic Colitis
Authors: Z Noor, K Watanabe, MM Abhyankar, SL Burgess, EL Buonomo, CA Cowardin, WA Petri
MBio, 2017;8(1):.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo -
Therapeutic Effectiveness of Anti-RAGE Antibody Administration in a Rat Model of Crush Injury
Authors: H Matsumoto, N Matsumoto, J Shimazaki, J Nakagawa, Y Imamura, K Yamakawa, T Yamada, M Ikeda, H Hiraike, H Ogura, T Shimazu
Sci Rep, 2017;7(1):12255.
Species: Rat
Sample Types: Whole Tissue
Applications: IHC -
TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus
Authors: Y Kannan, LJ Entwistle, VS Pelly, J Perez-Llor, AW Walker, SC Ley, MS Wilson
PLoS Pathog., 2017;13(7):e1006536.
Species: Mouse
Sample Types: In Vivo
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Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth
Authors: Y Shi, YF Ping, W Zhou, ZC He, C Chen, BS Bian, L Zhang, L Chen, X Lan, XC Zhang, K Zhou, Q Liu, H Long, TW Fu, XN Zhang, MF Cao, Z Huang, X Fang, X Wang, H Feng, XH Yao, SC Yu, YH Cui, X Zhang, JN Rich, S Bao, XW Bian
Nat Commun, 2017;8(0):15080.
Species: Human
Sample Types: Whole Cells
Applications: Flow -
Intestinal commensal bacteria mediate lung mucosal immunity and promote resistance of newborn mice to infection
Authors: J Gray, K Oehrle, G Worthen, T Alenghat, J Whitsett, H Deshmukh
Sci Transl Med, 2017;9(376):.
Species: Mouse
Sample Types: In Vivo
Applications: Isotype control -
p16Ink4a and p21Cip1/Waf1 promote tumour growth by enhancing myeloid-derived suppressor cells chemotaxis
Authors: A Okuma, A Hanyu, S Watanabe, E Hara
Nat Commun, 2017;8(1):2050.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Targeting GM-CSF in epithelial and vascular remodeling in experimental Eosinophilic Esophagitis
Authors: Eóin N McNamee
Allergy, 2016;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
NKG2D-NKG2D Ligand Interaction Inhibits the Outgrowth of Naturally Arising Low-Grade B Cell Lymphoma In Vivo
J Immunol, 2016;196(11):4805-13.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow -
Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD
Authors: Hoeke A Baarsma
J. Exp. Med, 2016;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin
Nat. Immunol., 2016;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo -
Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair
Authors: Jennifer Quantius
PLoS Pathog, 2016;12(6):e1005544.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Flow -
A TLR9 agonist promotes IL-22-dependent pancreatic islet allograft survival in type 1 diabetic mice
Nat Commun, 2016;7(0):13896.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow -
Basophils promote tumor rejection via chemotaxis and infiltration of CD8+ T cells
Cancer Res., 2016;0(0):.
Species: Mouse
Sample Types: In Vivo
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CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima
Nat Immunol, 2016;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Neut -
Dietary phosphate supplement does not rescue skeletal phenotype in a mouse model for craniometaphyseal dysplasia
Authors: I-Ping Chen
J Negat Results Biomed, 2016;15(1):18.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
IL-17A Is an Important Effector of the Immune Response of the Mammary Gland to Escherichia coli Infection.
Authors: Porcherie A, Gilbert F, Germon P, Cunha P, Trotereau A, Rossignol C, Winter N, Berthon P, Rainard P
J Immunol, 2016;196(2):803-12.
Species: Mouse
Sample Types: Whole Cells
Applications: Neut Ctrl -
Seminal plasma induces inflammation in the uterus through the ?? T/IL-17 pathway
Authors: ZH Song, ZY Li, DD Li, WN Fang, HY Liu, DD Yang, CY Meng, Y Yang, JP Peng
Sci Rep, 2016;6(0):25118.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo -
Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis
Authors: D Schlam, J Canton, M Carreño, H Kopinski, SA Freeman, S Grinstein, GD Fairn
MBio, 2016;7(2):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow -
A Herpesviral induction of RAE-1 NKG2D ligand expression occurs through release of HDAC mediated repression
Elife, 2016;5(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow -
Tick-borne encephalitis virus induces chemokine RANTES expression via activation of IRF-3 pathway
J Neuroinflammation, 2016;13(1):209.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo control -
Neutrophils suppress intraluminal NK-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells
Authors: A Spiegel, MW Brooks, S Houshyar, F Reinhardt, M Ardolino, E Fessler, MB Chen, JA Krall, J DeCock, IK Zervantona, A Iannello, Y Iwamoto, V Cortez-Ret, RD Kamm, MJ Pittet, DH Raulet, RA Weinberg
Cancer Discov, 2016;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Thymic Stromal Lymphopoietin Neutralization Inhibits the Immune Adjuvant Effect of Di-(2-Ethylhexyl) Phthalate in Balb/c Mouse Asthma Model
PLoS ONE, 2016;11(7):e0159479.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
Allostimulatory Effects of Dendritic Cells with Characteristic Features of a Regulatory Phenotype
PLoS ONE, 2016;11(8):e0159986.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay Ctrl -
Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy.
Authors: Barreira da Silva R, Laird M, Yatim N, Fiette L, Ingersoll M, Albert M
Nat Immunol, 2015;16(8):850-8.
Species: Mouse
Sample Types: In Vivo
Applications: Neut -
Static stretch affects neural stem cell differentiation in an extracellular matrix-dependent manner.
Authors: Arulmoli J, Pathak M, McDonnell L, Nourse J, Tombola F, Earthman J, Flanagan L
Sci Rep, 2015;5(0):8499.
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Dendritic Cells Regulate Treg-Th17 Axis in Obstructive Phase of Bile Duct Injury in Murine Biliary Atresia.
Authors: Liu Y, Li K, Yang L, Tang S, Wang X, Cao G, Li S, Lei H, Zhang X
PLoS ONE, 2015;10(9):e0136214.
Species: Mouse
Sample Types: In Vivo
Applications: Neut Ctrl -
Tumor-induced pressure in the bone microenvironment causes osteocytes to promote the growth of prostate cancer bone metastases.
Authors: Sottnik J, Dai J, Zhang H, Campbell B, Keller E
Cancer Res, 2015;75(11):2151-8.
Species: Human
Sample Types: Whole Cells
Applications: Neut Ctrl -
Immune complexes regulate bone metabolism through FcRgamma signalling.
Authors: Negishi-Koga T, Gober H, Sumiya E, Komatsu N, Okamoto K, Sawa S, Suematsu A, Suda T, Sato K, Takai T, Takayanagi H
Nat Commun, 2015;6(0):6637.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow -
The calcineurin-NFAT axis controls allograft immunity in myeloid-derived suppressor cells through reprogramming T cell differentiation.
Authors: Wang X, Bi Y, Xue L, Liao J, Chen X, Lu Y, Zhang Z, Wang J, Liu H, Yang H, Liu G
Mol Cell Biol, 2015;35(3):598-609.
Species: Mouse
Sample Types: In Vivo
Applications: Neut -
Critical role for IL-18 in spontaneous lung inflammation caused by autophagy deficiency.
Authors: Abdel Fattah E, Bhattacharya A, Herron A, Safdar Z, Eissa N
J Immunol, 2015;194(11):5407-16.
Species: Mouse
Sample Types: In Vivo
Applications: Neut Ctrl -
Neonatal Streptococcus pneumoniae infection may aggravate adulthood allergic airways disease in association with IL-17A.
Authors: Yang B, Liu R, Yang T, Jiang X, Zhang L, Wang L, Wang Q, Luo Z, Liu E, Fu Z
PLoS ONE, 2015;10(3):e0123010.
Species: Mouse
Sample Types: In Vivo
Applications: Neut Ctrl -
NADPH oxidase-independent formation of extracellular DNA traps by basophils.
Authors: Morshed M, Hlushchuk R, Simon D, Walls A, Obata-Ninomiya K, Karasuyama H, Djonov V, Eggel A, Kaufmann T, Simon H, Yousefi S
J Immunol, 2014;192(11):5314-23.
Species: Mouse
Sample Types: Whole Cells
Applications: Isotype control -
The role of host and microbial factors in the pathogenesis of pneumococcal bacteraemia arising from a single bacterial cell bottleneck.
Authors: Gerlini A, Colomba L, Furi L, Braccini T, Manso A, Pammolli A, Wang B, Vivi A, Tassini M, Van Rooijen N, Pozzi G, Ricci S, Andrew P, Koedel U, Moxon E, Oggioni M
PLoS Pathog, 2014;10(3):e1004026.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow -
Eosinophils promote generation and maintenance of immunoglobulin-A-expressing plasma cells and contribute to gut immune homeostasis.
Authors: Chu V, Beller A, Rausch S, Strandmark J, Zanker M, Arbach O, Kruglov A, Berek C
Immunity, 2014;40(4):582-93.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo -
gammadelta T cells are required for pulmonary IL-17A expression after ozone exposure in mice: role of TNFalpha.
Authors: Mathews J, Williams A, Brand J, Wurmbrand A, Chen L, Ninin F, Si H, Kasahara D, Shore S
PLoS ONE, 2014;9(5):e97707.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo -
IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice.
Authors: Guabiraba R, Besnard A, Menezes G, Secher T, Jabir M, Amaral S, Braun H, Lima-Junior R, Ribeiro R, Cunha F, Teixeira M, Beyaert R, Graham G, Liew F
Mucosal Immunol, 2014;7(5):1079-93.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo -
Nitric oxide regulates BAFF expression and T cell-independent antibody responses.
Authors: Giordano D, Draves K, Li C, Hohl T, Clark E
J Immunol, 2014;193(3):1110-20.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow -
mTOR limits the recruitment of CD11b+Gr1+Ly6Chigh myeloid-derived suppressor cells in protecting against murine immunological hepatic injury.
Authors: Zhang Y, Bi Y, Yang H, Chen X, Liu H, Lu Y, Zhang Z, Liao J, Yang S, Chu Y, Yang R, Liu G
J Leukoc Biol, 2014;95(6):961-70.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo -
Retinoic acid prevents mesenteric lymph node dendritic cells from inducing IL-13-producing inflammatory Th2 cells.
Authors: Yokota-Nakatsuma A, Takeuchi H, Ohoka Y, Kato C, Song S, Hoshino T, Yagita H, Ohteki T, Iwata M
Mucosal Immunol, 2014;7(4):786-801.
Species: Mouse
Sample Types: Whole Cells
Applications: Isotype control -
MULT1E/mIL-12: a novel bifunctional protein for natural killer cell activation.
Authors: Tietje A, Li J, Yu X, Wei Y
Gene Ther, 2014;21(5):468-75.
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: ELISA Development -
Interleukin-17A modulates circulating tumor cells in tumor draining vein of colorectal cancers and affects metastases.
Authors: Tseng J, Yang C, Liang S, Liu R, Yang S, Lin J, Chen Y, Wu Y, Jiang J, Lin C
Clin Cancer Res, 2014;20(11):2885-97.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo -
Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil- and CCL8-dependent manner.
Authors: Dulek D, Newcomb D, Goleniewska K, Cephus J, Zhou W, Reiss S, Toki S, Ye F, Zaynagetdinov R, Sherrill T, Blackwell T, Moore M, Boyd K, Kolls J, Peebles R
Infect Immun, 2014;82(9):3723-39.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo -
CCR6 is a prognostic marker for overall survival in patients with colorectal cancer, and its overexpression enhances metastasis in vivo.
Authors: Liu, Jinlin, Ke, Fang, Xu, Zhenyao, Liu, Zhaoyuan, Zhang, Lingyun, Yan, Sha, Wang, Zhe, Wang, Hong, Wang, Honglin
PLoS ONE, 2014;9(6):e101137.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo -
Syndecan-1 in the mouse parietal peritoneum microcirculation in inflammation.
Authors: Kowalewska P, Patrick A, Fox-Robichaud A
PLoS ONE, 2014;9(9):e104537.
Species: Mouse
Sample Types: In Vivo
Applications: IHC Fresh -
Differential role of lipocalin 2 during immune complex-mediated acute and chronic inflammation in mice.
Authors: Shashidharamurthy R, Machiah D, Aitken J, Putty K, Srinivasan G, Chassaing B, Parkos C, Selvaraj P, Vijay-Kumar M
Arthritis Rheum, 2013;65(4):1064-73.
Species: Mouse
Sample Types:
-
Engagement of two distinct binding domains on CCL17 is required for signaling through CCR4 and establishment of localized inflammatory conditions in the lung.
Authors: Santulli-Marotto S, Boakye K, Lacy E, Wu S, Luongo J, Kavalkovich K, Coelho A, Hogaboam C, Ryan M
PLoS ONE, 2013;8(12):e81465.
Species: Mouse
Sample Types: Recombinant Protein
Applications: Bioassay -
Interleukin-33 and alveolar macrophages contribute to the mechanisms underlying the exacerbation of IgE-mediated airway inflammation and remodelling in mice.
Authors: Mizutani N, Nabe T, Yoshino S
Immunology, 2013;139(2):205-18.
Species: Mouse
Sample Types: In Vivo
Applications: Isotype control -
Galectin-9 functionally impairs natural killer cells in humans and mice.
Authors: Golden-Mason L, McMahan R, Strong M, Reisdorph R, Mahaffey S, Palmer B, Cheng L, Kulesza C, Hirashima M, Niki T, Rosen H
J Virol, 2013;87(9):4835-45.
Species: Human
Sample Types: Whole Cells
Applications: Neut -
Respiratory syncytial virus reverses airway hyperresponsiveness to methacholine in ovalbumin-sensitized mice.
Authors: Aeffner F, Davis I
PLoS ONE, 2012;7(10):e46660.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
Inducible IL-33 expression by mast cells is regulated by a calcium-dependent pathway.
Authors: Hsu C, Bryce P
J Immunol, 2012;189(7):3421-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Ctrl -
CXCL1 can be regulated by IL-6 and promotes granulocyte adhesion to brain capillaries during bacterial toxin exposure and encephalomyelitis.
Authors: Roy M, Richard JF, Dumas A, Vallieres L
J Neuroinflammation, 2012;9(0):18.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma.
Authors: Blotta, Simona, Jakubikova, Jana, Calimeri, Teresa, Roccaro, Aldo M, Amodio, Nicola, Azab, Abdel Ka, Foresta, Umberto, Mitsiades, Constant, Rossi, Marco, Todoerti, Katia, Molica, Stefano, Morabito, Fortunat, Neri, Antonino, Tagliaferri, Piersand, Tassone, Pierfran, Anderson, Kenneth, Munshi, Nikhil C
Blood, 2012;120(25):5002-13.
Species: Human
Sample Types: Whole Cells
Applications: Flow control -
IL-23 is required for long-term control of Mycobacterium tuberculosis and B cell follicle formation in the infected lung.
Authors: Khader SA, Guglani L, Rangel-Moreno J
J. Immunol., 2011;187(10):5402-7.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
The ageing systemic milieu negatively regulates neurogenesis and cognitive function.
Authors: Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A, Lucin KM, Czirr E, Park JS, Couillard-Despres S, Aigner L, Li G, Peskind ER, Kaye JA, Quinn JF, Galasko DR, Xie XS, Rando TA, Wyss-Coray T
Nature, 2011;477(7362):90-4.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
TNF-alpha promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines.
Authors: Zhao C, Sardella A, Chun J, Poubelle PE, Fernandes MJ, Bourgoin SG
J. Lipid Res., 2011;52(7):1307-18.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells.
Authors: Islam SA, Chang DS, Colvin RA
Nat. Immunol., 2011;12(2):167-77.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
IL-33 is produced by mast cells and regulates IgE-dependent inflammation.
Authors: Hsu CL, Neilsen CV, Bryce PJ
PLoS ONE, 2010;5(8):e11944.
Species: Mouse
Sample Types: Whole Cells
Applications: Ctrl -
IL-17A-producing gammadelta T and Th17 lymphocytes mediate lung inflammation but not fibrosis in experimental silicosis.
Authors: Lo Re S, Dumoutier L, Couillin I, Van Vyve C, Yakoub Y, Uwambayinema F, Marien B, van den Brule S, Van Snick J, Uyttenhove C, Ryffel B, Renauld JC, Lison D, Huaux F
J. Immunol., 2010;184(11):6367-77.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
Molecular immune responses to aerosol challenge with Francisella tularensis in mice inoculated with live vaccine candidates of varying efficacy.
Authors: Shen H, Harris G, Chen W, Sjostedt A, Ryden P, Conlan W
PLoS ONE, 2010;5(10):e13349.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
Chlamydial respiratory infection during allergen sensitization drives neutrophilic allergic airways disease.
Authors: Horvat JC, Starkey MR, Kim RY, Beagley KW, Preston JA, Gibson PG, Foster PS, Hansbro PM
J. Immunol., 2010;184(8):4159-69.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
Innate immune activation during Salmonella infection initiates extramedullary erythropoiesis and splenomegaly.
Authors: Jackson A, Nanton MR, O'Donnell H
J. Immunol., 2010;185(10):6198-204.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
Protective role of interleukin-17 in murine NKT cell-driven acute experimental hepatitis.
Authors: Wondimu Z, Santodomingo-Garzon T, Le T, Swain MG
Am. J. Pathol., 2010;177(5):2334-46.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
Patched1 inhibits epidermal progenitor cell expansion and basal cell carcinoma formation by limiting Igfbp2 activity.
Authors: Villani RM, Adolphe C, Palmer J, Waters MJ, Wainwright BJ
Cancer Prev Res (Phila), 2010;3(10):1222-34.
Species: Mouse
Sample Types: Whole Tissue
Applications: Ctrl -
Dynamic macrophage "probing" is required for the efficient capture of phagocytic targets.
Authors: Flannagan RS, Harrison RE, Yip CM, Jaqaman K, Grinstein S
J. Cell Biol., 2010;191(6):1205-18.
Species: Mouse
Sample Types:
Applications: Flow control -
A critical function of Th17 proinflammatory cells in the development of atherosclerotic plaque in mice.
Authors: Gao Q, Jiang Y, Ma T, Zhu F, Gao F, Zhang P, Guo C, Wang Q, Wang X, Ma C, Zhang Y, Chen W, Zhang L
J. Immunol., 2010;185(10):5820-7.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
IL-17/Th17 promotes type 1 T cell immunity against pulmonary intracellular bacterial infection through modulating dendritic cell function.
Authors: Bai H, Cheng J, Gao X, Joyee AG, Fan Y, Wang S, Jiao L, Yao Z, Yang X
J. Immunol., 2009;183(9):5886-95.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production.
Authors: Lemos HP, Grespan R, Vieira SM, Cunha TM, Verri WA, Fernandes KS, Souto FO, McInnes IB, Ferreira SH, Liew FY, Cunha FQ
Proc. Natl. Acad. Sci. U.S.A., 2009;106(14):5954-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Ctrl -
Junctional adhesion molecule (JAM)-B supports lymphocyte rolling and adhesion through interaction with alpha4beta1 integrin.
Authors: Ludwig RJ, Hardt K, Hatting M, Bistrian R, Diehl S, Radeke HH, Podda M, Schon MP, Kaufmann R, Henschler R, Pfeilschifter JM, Santoso S, Boehncke WH
Immunology, 2009;128(2):196-205.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
Expression of the ULBP ligands for NKG2D by B-NHL cells plays an important role in determining their susceptibility to rituximab-induced ADCC.
Authors: Inagaki A, Ishida T, Yano H, Ishii T, Kusumoto S, Ito A, Ri M, Mori F, Ding J, Komatsu H, Iida S, Ueda R
Int. J. Cancer, 2009;125(1):212-21.
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Encephalitogenicity of complete Freund's adjuvant relative to CpG is linked to induction of Th17 cells.
Authors: Tigno-Aranjuez JT, Jaini R, Tuohy VK, Lehmann PV, Tary-Lehmann M
J. Immunol., 2009;183(9):5654-61.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
Absence of functional Hfe protects mice from invasive Salmonella enterica serovar Typhimurium infection via induction of lipocalin-2.
Authors: Nairz M, Theurl I, Schroll A, Theurl M, Fritsche G, Lindner E, Seifert M, Crouch ML, Hantke K, Akira S, Fang FC, Weiss G
Blood, 2009;114(17):3642-51.
Species: Mouse
Sample Types: Serum
Applications: Ctrl -
A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses.
Authors: Wu S, Rhee KJ, Albesiano E, Rabizadeh S, Wu X, Yen HR, Huso DL, Brancati FL, Wick E, McAllister F, Housseau F, Pardoll DM, Sears CL
Nat. Med., 2009;15(9):1016-22.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum.
Authors: Zhang X, Gao L, Lei L, Zhong Y, Dube P, Berton MT, Arulanandam B, Zhang J, Zhong G
J. Immunol., 2009;183(2):1291-300.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation.
Authors: Boehme SA, Franz-Bacon K, Chen EP, Sasik R, Sprague LJ, Ly TW, Hardiman G, Bacon KB
Int. Immunol., 2009;21(1):81-93.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia.
Authors: Lagler H, Sharif O, Haslinger I, Matt U, Stich K, Furtner T, Doninger B, Schmid K, Gattringer R, de Vos AF, Knapp S
J. Immunol., 2009;183(3):2027-36.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
Salmonella disrupts lymph node architecture by TLR4-mediated suppression of homeostatic chemokines.
Authors: St John AL, Abraham SN
Nat. Med., 2009;15(11):1259-65.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.
Authors: D'Angelo C, Segal BH
Nature, 2008;451(7175):211-5.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection.
Authors: Bozza S, Zelante T, Moretti S, Bonifazi P, DeLuca A, D'Angelo C, Giovannini G, Garlanda C, Boon L, Bistoni F, Puccetti P, Mantovani A, Romani L
J. Immunol., 2008;180(6):4022-31.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
Excreted urinary mediators in an animal model of experimental immune nephritis with potential pathogenic significance.
Authors: Wu T, Xie C, Bhaskarabhatla M, Yan M, Leone A, Chen SS, Zhou XJ, Putterman C, Mohan C
Arthritis Rheum., 2007;56(3):949-59.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
iNKT cells require CCR4 to localize to the airways and to induce airway hyperreactivity.
Authors: Meyer EH, Wurbel MA, Staton TL, Pichavant M, Kan MJ, Savage PB, DeKruyff RH, Butcher EC, Campbell JJ, Umetsu DT
J. Immunol., 2007;179(7):4661-71.
Species: Mouse
Sample Types: Whole Cells
Applications: Ctrl -
Keratocan and lumican regulate neutrophil infiltration and corneal clarity in lipopolysaccharide-induced keratitis by direct interaction with CXCL1.
Authors: Carlson EC, Lin M, Liu CY, Kao WW, Perez VL, Pearlman E
J. Biol. Chem., 2007;282(49):35502-9.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Ctrl -
Anti-type II collagen antibody accelerates arthritis via CXCR2-expressing cells in IL-1 receptor antagonist-deficient mice.
Authors: Kagari T, Tanaka D, Doi H, Iwakura Y, Shimozato T
Eur. J. Immunol., 2007;37(10):2753-63.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge.
Authors: He R, Oyoshi MK, Jin H, Geha RS
Proc. Natl. Acad. Sci. U.S.A., 2007;104(40):15817-22.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells.
Authors: Zheng SG, Wang J, Wang P, Gray JD, Horwitz DA
J. Immunol., 2007;178(4):2018-27.
Species: Mouse
Sample Types: Whole Cells
Applications: Ctrl -
TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells.
Authors: Higgins SC, Jarnicki AG, Lavelle EC, Mills KH
J. Immunol., 2006;177(11):7980-9.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl -
A role for activation-induced cytidine deaminase in the host response against a transforming retrovirus.
Authors: Gourzi P, Leonova T, Papavasiliou FN
Immunity, 2006;24(6):779-86.
Species: Mouse
Sample Types: Whole Cells
Applications: Ctrl -
A new RXR agonist, HX630, suppresses intimal hyperplasia in a mouse blood flow cessation model.
Authors: Haraguchi G, Suzuki J, Kosuge H, Ogawa M, Koga N, Muto S, Itai A, Kagechika H, Shudo K, Isobe M
J. Mol. Cell. Cardiol., 2006;41(5):885-92.
Species: Mouse
Sample Types: Whole Tissue
Applications: Ctrl -
Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines.
Authors: Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck LA, Lamkhioued B
Clin. Immunol., 2006;120(2):220-31.
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Cytokine receptor-mediated trafficking of preformed IL-4 in eosinophils identifies an innate immune mechanism of cytokine secretion.
Authors: Spencer LA, Melo RC, Perez SA, Bafford SP, Dvorak AM, Weller PF
Proc. Natl. Acad. Sci. U.S.A., 2006;103(9):3333-8.
Species: Human
Sample Types: Whole Cells
Applications: Ctrl -
Rapid up-regulation of CXC chemokines in the airways after Ag-specific CD4+ T cell activation.
Authors: Knott PG, Gater PR, Dunford PJ, Fuentes ME, Bertrand CP
J. Immunol., 2001;166(2):1233-40.
Species: Mouse
Sample Types: In Vivo
Applications: Ctrl
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