Rat IgG2A Isotype Control

The contribution of IL-17A-dependent low LCN2 levels to Helicobacter pylori infection: Insights from clinical and experimental studies
Authors: Cheng, M;Zheng, Y;Fan, Y;Yan, P;Zhao, W;
International immunopharmacology
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization Control

IL-3 orchestrates ulcerative colitis pathogenesis by controlling the development and the recruitment of splenic reservoir neutrophils
Authors: Bénard, A;Mittelstädt, A;Klösch, B;Glanz, K;Müller, J;Schoen, J;Nüse, B;Brunner, M;Naschberger, E;Stürzl, M;Mattner, J;Muñoz, LE;Sohn, K;Grützmann, R;Weber, GF;
Cell reports
Species: Mouse
Sample Types:
Applications: In Vivo

Obstructive Sleep Apnea-Induced Hypertension Is Associated With Increased Gut and Neuroinflammation
Authors: Ayyaswamy, S;Shi, H;Zhang, B;Bryan, RM;Durgan, DJ;
Journal of the American Heart Association
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Interleukin-9 promotes mast cell progenitor proliferation and CCR2-dependent mast cell migration in allergic airway inflammation
Authors: Pajulas, A;Fu, Y;Cheung, CCL;Chu, M;Cannon, A;Alakhras, N;Zhang, J;Ulrich, BJ;Nelson, AS;Zhou, B;Kaplan, MH;
Mucosal immunology
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo Control

Immunotherapy targeting plasma ASM is protective in a mouse model of Alzheimer's disease
Authors: BJ Choi, MH Park, KH Park, WH Han, HJ Yoon, HY Jung, JY Hong, MR Chowdhury, KY Kim, J Lee, IS Song, M Pang, MK Choi, E Gulbins, M Reichel, J Kornhuber, CW Hong, C Kim, SH Kim, EH Schuchman, HK Jin, JS Bae
Nature Communications, 2023-03-24;14(1):1631.
Species: Mouse
Sample Types: In Vivo
Applications: Isotype Control

The Role of C-X-C Chemokines in Staphylococcus aureus Endophthalmitis
Authors: PS Coburn, AC Parrott, FC Miller, AL LaGrow, MH Mursalin, MC Callegan
Investigative Ophthalmology & Visual Science, 2023-03-01;64(3):10.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Spatiotemporal regulation of cholangiocarcinoma growth and dissemination by peritumoral myofibroblasts in a Vcam1-dependent manner
Authors: C Tian, L Li, Q Pan, B Xu, Y Li, L Fan, A Brown, M Morrison, K Dey, JJ Yang, J Yu, ES Glazer, L Zhu
Oncogene, 2023-02-24;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo Control

Schwann cell-derived CXCL2 contributes to cancer pain by modulating macrophage infiltration in a mouse breast cancer model
Authors: Y Zhang, R Sang, J Bao, Z Jiang, D Qian, Y Zhou, W Su, J Wei, L Zhao, Z Wei, Y Zhao, M Shi, G Chen
Brain, Behavior, and Immunity, 2023-02-06;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Isotype Control

Role of MR1-driven signals and amphiregulin on the recruitment and repair function of MAIT cells during skin wound healing
Authors: Anastasia du Halgouet, Aurélie Darbois, Mansour Alkobtawi, Martin Mestdagh, Aurélia Alphonse, Virginie Premel et al.
Immunity

T cell-mediated elimination of cancer cells by blocking CEACAM6–CEACAM1 interaction
Authors: Jessica Pinkert, Hans-Henning Boehm, Mark Trautwein, Wolf-Dietrich Doecke, Florian Wessel, Yingzi Ge et al.
OncoImmunology

Loss of SLC26A3 Results in Colonic Mucosal Immune Dysregulation via Epithelial-Immune Cell Crosstalk
Authors: D Jayawarden, S Priyamvada, T Kageyama, Z White, A Kumar, TF Griggs, A Majumder, R Akram, AN Anbazhagan, T Sano, PK Dudeja
Cellular and Molecular Gastroenterology and Hepatology, 2022-12-17;0(0):.
Species: Mouse, Transgenic Mouse
Sample Types: In Vivo
Applications: In Vivo

Lcn2 mediates adipocyte-muscle-tumor communication and hypothermia in pancreatic cancer cachexia
Authors: Mengistu Lemecha, Jaya Prakash Chalise, Yuki Takamuku, Guoxiang Zhang, Takahiro Yamakawa, Garrett Larson et al.
Molecular Metabolism
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

Immunoglobulin somatic hypermutation in a defined biochemical system recapitulates affinity maturation and permits antibody optimization
Authors: SL Jeong, H Zhang, S Yamaki, C Yang, DD McKemy, MR Lieber, P Pham, MF Goodman
Nucleic Acids Research, 2022-11-11;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo Control

Single-cell RNA transcriptome analysis of CNS immune cells reveals CXCL16/CXCR6 as maintenance factors for tissue-resident T cells that drive synapse elimination
Authors: Sarah F. Rosen, Allison L. Soung, Wei Yang, Shenjian Ai, Marlene Kanmogne, Veronica A. Davé et al.
Genome Medicine

Inflammation triggers ILC3 patrolling of the intestinal barrier
Authors: A Jarade, Z Garcia, S Marie, A Demera, I Prinz, P Bousso, JP Di Santo, N Serafini
Nature Immunology, 2022-08-23;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Enteric glial adenosine 2B receptor signaling mediates persistent epithelial barrier dysfunction following acute DSS colitis
Authors: V Grubiši?, V Bali, DE Fried, HK Eltzschig, SC Robson, MS Mazei-Robi, BD Gulbransen
Mucosal Immunology, 2022-07-22;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization Control

Extracellular CIRP Promotes GPX4-Mediated Ferroptosis in Sepsis
Authors: Junji Shimizu, Atsushi Murao, Colleen Nofi, Ping Wang, Monowar Aziz
Frontiers in Immunology
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization Control

miR-188-3p targets skeletal endothelium coupling of angiogenesis and osteogenesis during ageing
Authors: WZ He, M Yang, Y Jiang, C He, YC Sun, L Liu, M Huang, YR Jiao, KX Chen, J Hou, M Huang, YL Xu, X Feng, Y Liu, Q Guo, H Peng, Y Huang, T Su, Y Xiao, Y Li, C Zeng, G Lei, XH Luo, CJ Li
Cell Death & Disease, 2022-05-25;13(5):494.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC Control

Meningeal lymphatics regulate radiotherapy efficacy through modulating anti-tumor immunity
Authors: Changping Zhou, Lu Ma, Han Xu, Yingqing Huo, Jincai Luo
Cell Research

Early non-neutralizing, afucosylated antibody responses are associated with COVID-19 severity
Authors: Saborni Chakraborty, Joseph C. Gonzalez, Benjamin L. Sievers, Vamsee Mallajosyula, Srijoni Chakraborty, Megha Dubey et al.
Science Translational Medicine

Investigating the Role of Artemin and Its Cognate Receptor, GFR alpha 3, in Osteoarthritis Pain
Authors: Laura Minnema, Ankita Gupta, Santosh K. Mishra, B. Duncan X. Lascelles
Frontiers in Neuroscience

TGF-?-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures
Authors: Chaurio RA, Anadon CM, Lee Costich T et al.
Immunity

Maternal gut bacteria drives intestinal inflammation in offspring with neurodevelopmental disorders by altering the chromatin landscape of CD4+ T cells
Authors: Eunha Kim, Donggi Paik, Ricardo N. Ramirez, Delaney G. Biggs, Youngjun Park, Ho-Keun Kwon et al.
Immunity

DCN released from ferroptotic cells ignites AGER-dependent immune responses
Authors: J Liu, S Zhu, L Zeng, J Li, DJ Klionsky, G Kroemer, J Jiang, D Tang, R Kang
Autophagy, 2021-12-29;0(0):1-14.
Species: Mouse
Sample Types: In Vivo
Applications: Isotype Control

A targetable LIFR-NF-kappaB-LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis
Authors: F Yao, Y Deng, Y Zhao, Y Mei, Y Zhang, X Liu, C Martinez, X Su, RR Rosato, H Teng, Q Hang, S Yap, D Chen, Y Wang, MM Chen, M Zhang, H Liang, D Xie, X Chen, H Zhu, JC Chang, MJ You, Y Sun, B Gan, L Ma
Nature Communications, 2021-12-17;12(1):7333.
Species: Mouse
Sample Types: In Vivo
Applications: Isotype Control

Direct CCL4 Inhibition Modulates Gut Microbiota, Reduces Circulating Trimethylamine N-Oxide, and Improves Glucose and Lipid Metabolism in High-Fat-Diet-Induced Diabetes Mellitus
Authors: Ting-Ting Chang, Jaw-Wen Chen
Journal of Inflammation Research

C-X-C Chemokines Influence Intraocular Inflammation During Bacillus Endophthalmitis
Authors: MH Mursalin, PS Coburn, FC Miller, ET Livingston, R Astley, MC Callegan
Investigative Ophthalmology & Visual Science, 2021-11-01;62(14):14.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

HIV-1 Nef Induces Hck/Lyn-Dependent Expansion of Myeloid-Derived Suppressor Cells Associated with Elevated Interleukin-17/G-CSF Levels
Authors: Elena Priceputu, Marc Cool, Nathalie Bouchard, Julio Roberto Caceres-Cortes, Clifford A. Lowell, Zaher Hanna et al.
Journal of Virology

CXCL10/CXCR3 signaling contributes to an inflammatory microenvironment and its blockade enhances progression of murine pancreatic precancerous lesions
Authors: Veethika Pandey, Alicia Fleming-Martinez, Ligia Bastea, Heike R Doeppler, Jillian Eisenhauer, Tam Le et al.
eLife

Tenascin-C-mediated suppression of extracellular matrix adhesion force promotes entheseal new bone formation through activation of Hippo signalling in ankylosing spondylitis
Authors: Zihao Li, Siwen Chen, Haowen Cui, Xiang Li, Dongying Chen, Wenjun Hao et al.
Annals of the Rheumatic Diseases
Species: Mouse, Transgenic Mouse
Sample Types: In Vivo
Applications: Neutralization Control

XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis
Authors: A Deczkowska, E David, P Ramadori, D Pfister, M Safran, B At The, A Giladi, DA Jaitin, O Barboy, M Cohen, I Yofe, C Gur, S Shlomi-Lou, S Henri, Y Suhail, M Qiu, S Kam, H Hermon, E Lahat, G Ben Yakov, O Cohen-Ezra, Y Davidov, M Likhter, D Goitein, S Roth, A Weber, B Malissen, A Weiner, Z Ben-Ari, M Heikenwäld, E Elinav, I Amit
Nature Medicine, 2021-05-20;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

A Novel Resolution of Diabetes: C-C Chemokine Motif Ligand 4 Is a Common Target in Different Types of Diabetes by Protecting Pancreatic Islet Cell and Modulating Inflammation
Authors: Ting-Ting Chang, Liang-Yu Lin, Jaw-Wen Chen
Frontiers in Immunology

Il4ra-independent vaginal eosinophil accumulation following helminth infection exacerbates epithelial ulcerative pathology of HSV-2 infection
Authors: Alisha Chetty, Matthew G. Darby, Pia M. Vornewald, Mara Martín-Alonso, Anna Filz, Manuel Ritter et al.
Cell Host & Microbe

Helicobacter pylori-induced Rev-erb&alpha fosters gastric bacteria colonization by impairing host innate and adaptive defense
Authors: FY Mao, YP Lv, CJ Hao, YS Teng, YG Liu, P Cheng, SM Yang, W Chen, T Liu, QM Zou, R Xie, JY Xu, Y Zhuang
Cellular and Molecular Gastroenterology and Hepatology, 2021-03-03;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

Radiation-induced eosinophils improve cytotoxic T lymphocyte recruitment and response to immunotherapy
Authors: Jia-Nan Cheng, Wen Luo, Chengdu Sun, Zheng Jin, Xianghua Zeng, Peter B. Alexander et al.
Science Advances
Species: Mouse
Sample Types: In Vivo
Applications: In vivo assay

TREM-1 orchestrates angiotensin II–induced monocyte trafficking and promotes experimental abdominal aortic aneurysm
Authors: Marie Vandestienne, Yujiao Zhang, Icia Santos-Zas, Rida Al-Rifai, Jeremie Joffre, Andreas Giraud et al.
Journal of Clinical Investigation
Species: Mouse
Sample Types: In Vivo
Applications: In vivo assay

The metalloproteinase ADAM10 requires its activity to sustain surface expression
Authors: Anke Seifert, Stefan Düsterhöft, Justyna Wozniak, Chek Z. Koo, Michael G. Tomlinson, Elisa Nuti et al.
Cellular and Molecular Life Sciences

IL-17A Contributes to Lung Fibrosis in a Model of Chronic Pulmonary Graft-versus-host Disease
Authors: Tereza Martinu, William C. McManigle, Francine L. Kelly, Margaret E. Nelson, Jesse Sun, Helen L. Zhang et al.
Transplantation

Targeted-Alpha-Therapy Combining Astatine-211 and anti-CD138 Antibody in A Preclinical Syngeneic Mouse Model of Multiple Myeloma Minimal Residual Disease
Authors: S Gouard, C Maurel, S Marionneau, D Dansette, C Bailly, F Guérard, N Chouin, F Haddad, C Alliot, J Gaschet, R Eychenne, F Kraeber-Bo, M Chérel
Cancers, 2020-09-22;12(9):.
Species: Mouse
Sample Types: Reference Standard
Applications: Isotype Control

CCL4 Inhibition in Atherosclerosis: Effects on Plaque Stability, Endothelial Cell Adhesiveness, and Macrophages Activation
Authors: Chang TT, Yang HY, Chen C, Chen JW.
International Journal of Molecular Sciences

Tenascin-C Orchestrates an Immune-Suppressive Tumor Microenvironment in Oral Squamous Cell Carcinoma
Authors: Caroline Spenlé, Thomas Loustau, Devadarssen Murdamoothoo, William Erne, Stephanie Beghelli-de la Forest Divonne, Romain Veber et al.
Cancer Immunology Research
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization Control

Neutralization of Lipocalin-2 Diminishes Stroke-Reperfusion Injury
Authors: Guona Wang, Yi-Chinn Weng, I-Chen Chiang, Yu-Ting Huang, Yi-Chu Liao, Yi-Chun Chen et al.
International Journal of Molecular Sciences

CDK4/6 inhibition promotes immune infiltration in ovarian cancer and synergizes with PD-1 blockade in a B cell-dependent manner
Authors: QF Zhang, J Li, K Jiang, R Wang, JL Ge, H Yang, SJ Liu, LT Jia, L Wang, BL Chen
Theranostics, 2020-08-25;10(23):10619-10633.
Species: Mouse
Sample Types: Whole Cells
Applications: Control

Paneth Cell-Derived Lysozyme Defines the Composition of Mucolytic Microbiota and the Inflammatory Tone of the Intestine
Authors: Shiyan Yu, Iyshwarya Balasubramanian, Daniel Laubitz, Kevin Tong, Sheila Bandyopadhyay, Xiang Lin et al.
Immunity
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization Control

The Innate Immune Response to Infection Induces Erythropoietin-Dependent Replenishment of the Dendritic Cell Compartment
Authors: Henrik Einwächter, Alexander Heiseke, Andreas Schlitzer, Georg Gasteiger, Heiko Adler, David Voehringer et al.
Frontiers in Immunology

Androgens predispose males to monocyte-mediated immunopathology by inducing the expression of leukocyte recruitment factor CXCL1
Authors: J Sellau, M Groneberg, H Fehling, T Thye, S Hoenow, C Marggraff, M Weskamm, C Hansen, S Stanelle-B, S Kuehl, J Noll, V Wolf, NG Metwally, SH Hagen, C Dorn, J Wernecke, H Ittrich, E Tannich, T Jacobs, I Bruchhaus, M Altfeld, H Lotter
Nat Commun, 2020-07-10;11(1):3459.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

JAK3 restrains inflammatory responses and protects against periodontal disease through Wnt3a signaling
Authors: Lanhai Lü, Lan Yakoumatos, Junling Ren, Xiaoxian Duan, Huaxin Zhou, Zhen Gu et al.
The FASEB Journal

Minocycline reverses IL-17A/TRAF3IP2-mediated p38 MAPK/NF-kappaB/iNOS/NO-dependent cardiomyocyte contractile depression and death
Authors: T Yoshida, NA Das, AJ Carpenter, R Izadpanah, SA Kumar, S Gautam, SB Bender, U Siebenlist, B Chandrasek
Cell. Signal., 2020-06-15;73(0):109690.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization Control

Species-, organ- and cell-type-dependent expression of SPARCL1 in human and mouse tissues
Authors: A Klingler, D Regensburg, C Tenkerian, N Britzen-La, A Hartmann, M Stürzl, E Naschberge
PLoS ONE, 2020-05-21;15(5):e0233422.
Species: Mouse
Sample Types: Whole Tissue
Applications: Isotype Control

Astroglial TLR9 antagonism promotes chemotaxis and alternative activation of macrophages via modulation of astrocyte-derived signals: implications for spinal cord injury
Authors: L Li, L Ni, RF Heary, S Elkabes
J Neuroinflammation, 2020-02-25;17(1):73.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

Mesenchymal stem cell-derived CXCL16 promotes progression of gastric cancer cells by STAT3-mediated expression of Ror1
Authors: T Ikeda, M Nishita, K Hoshi, T Honda, Y Kakeji, Y Minami
Cancer Sci., 2020-02-25;111(4):1254-1265.
Species: Mouse
Sample Types:
Applications: Neutralization Control

Bone Morphogenetic Protein 4 Gene Therapy in Mice Inhibits Myeloma Tumor Growth, But Has a Negative Impact on Bone
Authors: Marita Westhrin, Toril Holien, Muhammad Zahoor, Siv Helen Moen, Glenn Buene, Berit Størdal et al.
JBMR Plus

MR1-Independent Activation of Human Mucosal-Associated Invariant T Cells by Mycobacteria
Authors: S Suliman, M Murphy, M Musvosvi, A Gela, EW Meermeier, H Geldenhuys, C Hopley, A Toefy, N Bilek, A Veldsman, WA Hanekom, JL Johnson, WH Boom, G Obermoser, H Huang, M Hatherill, DM Lewinsohn, E Nemes, TJ Scriba
J. Immunol., 2019-10-14;0(0):.
Species: Human
Sample Types: Whole Blood
Applications: Neutralization

Aryl Hydrocarbon Receptor Directly Regulates Artemin Gene Expression
Authors: Tomohiro Edamitsu, Keiko Taguchi, Eri H. Kobayashi, Ryuhei Okuyama, Masayuki Yamamoto
Molecular and Cellular Biology

Anti-thymic stromal lymphopoietin antibody suppresses airway remodeling in asthma through reduction of MMP and CTGF
Authors: Sheng-Chieh Lin, Hsiu-Chu Chou, Chung-Ming Chen, Bor-Luen Chiang
Pediatric Research

Sex differences in IL-17 contribute to chronicity in male versus female urinary tract infection
Authors: A Zychlinsky, M Rousseau, L Lacerda Ma, T Canton, CR Consiglio, ML Albert, M Fontes, D Duffy, MA Ingersoll
JCI Insight, 2019-05-30;5(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Galectin-3 promotes A&beta oligomerization and A&beta toxicity in a mouse model of Alzheimer's disease
Authors: CC Tao, KM Cheng, YL Ma, WL Hsu, YC Chen, JL Fuh, WJ Lee, CC Chao, EHY Lee
Cell Death Differ., 2019-05-24;27(1):192-209.
Species: Rat
Sample Types: Hippocampal Cell Lysates
Applications: IP

Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection
Authors: Mahmoud M. Saleh, Alyse L. Frisbee, Jhansi L. Leslie, Erica L. Buonomo, Carrie A. Cowardin, Jennie Z. Ma et al.
Cell Host & Microbe

Comparative Transcriptomic Analysis Identifies a Range of Immunologically Related Functional Elaborations of Lymph Node Associated Lymphatic and Blood Endothelial Cells
Authors: Stella J. Berendam, Alexander F. Koeppel, Nicole R. Godfrey, Sherin J. Rouhani, Amber N. Woods, Anthony B. Rodriguez et al.
Frontiers in Immunology

Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and therapeutic strategies
Authors: S An, I Raju, B Surenkhuu, JE Kwon, S Gulati, M Karaman, A Pradeep, S Sinha, C Mun, S Jain
Ocul Surf, 2019-04-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control

Neutrophil Extracellular Traps Promote Inflammatory Responses in Psoriasis via Activating Epidermal TLR4/IL-36R Crosstalk
Authors: Shuai Shao, Hui Fang, Erle Dang, Ke Xue, Jieyu Zhang, Bing Li et al.
Frontiers in Immunology

A20-binding inhibitor of NF-kappa B (ABIN) 2 negatively regulates allergic airway inflammation
Authors: Sonia Ventura, Florencia Cano, Yashaswini Kannan, Felix Breyer, Michael J. Pattison, Mark S. Wilson et al.
Journal of Experimental Medicine

Inhibition of CCL3 abrogated precursor cell fusion and bone erosions in human osteoclast cultures and murine collagen-induced arthritis
Authors: Lauren A Jordan, Malin C Erlandsson, Benjamin F Fenner, Ruth Davies, Ann K Harvey, Ernest H Choy et al.
Rheumatology (Oxford)

Therapeutic potential of tranilast for the treatment of chronic graft-versus-host disease in mice
Authors: S Mukai, Y Ogawa, H Saya, Y Kawakami, K Tsubota
PLoS ONE, 2018-10-11;13(10):e0203742.
Species: Mouse
Sample Types: Whole Tissue
Applications: Isotype Control

Amount of Mononuclear Phagocyte Infiltrate Does Not Predict Area of Experimental Choroidal Neovascularization (CNV)
Authors: Adrian Will-Orrego, Yubin Qiu, Elizabeth S. Fassbender, Siyuan Shen, Jorge Aranda, Namrata Kotagiri et al.
Journal of Ocular Pharmacology and Therapeutics

A Kaposi's Sarcoma-Associated Herpesvirus Infection Mechanism Is Independent of Integrins alpha 3 beta 1, alpha V beta 3, and alpha V beta 5
Authors: Allison Alwan TerBush, Florianne Hafkamp, Hee Jun Lee, Laurent Coscoy
Journal of Virology
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry Control

gamma δ T Cells Contribute to Injury in the Developing Brain
Authors: Anna-Maj Albertsson, Xiaoli Zhang, Regina Vontell, Dan Bi, Roderick T. Bronson, Veena Supramaniam et al.
The American Journal of Pathology

Estrogen Deficiency Promotes Cerebral Aneurysm Rupture by Upregulation of Th17 Cells and Interleukin-17A Which Downregulates E-Cadherin
Authors: BL Hoh, K Rojas, L Lin, HZ Fazal, S Hourani, KW Nowicki, MB Schneider, K Hosaka
J Am Heart Assoc, 2018-04-13;7(8):.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Inhibition of Vascular Adhesion Protein-1 for Treatment of Graft-Versus-Host Disease in Mice
Authors: S Mukai, Y Ogawa, Y Kawakami, Y Mashima, K Tsubota
FASEB J., 2018-02-28;0(0):fj201700176R.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr

Sonic Hedgehog Signaling Regulates Hematopoietic Stem/Progenitor Cell Activation during the Granulopoietic Response to Systemic Bacterial Infection
Authors: X Shi, S Wei, KJ Simms, DN Cumpston, TJ Ewing, P Zhang
Front Immunol, 2018-02-26;9(0):349.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry

Galectin-9 is Critical for Mucosal Adaptive Immunity through the TH17-IgA Axis
Authors: CC Liang, CS Li, IC Weng, HY Chen, HH Lu, CC Huang, FT Liu
Am. J. Pathol., 2018-02-17;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization Control

NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control
Authors: JP Böttcher, E Bonavita, P Chakravart, H Blees, M Cabeza-Cab, S Sammicheli, NC Rogers, E Sahai, S Zelenay, C Reis E Sou
Cell, 2018-02-08;172(5):1022-1037.e14.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Blockade of placental growth factor reduces vaso-occlusive complications in murine models of sickle cell disease
Authors: JM Gu, S Yuan, D Sim, K Abe, P Liu, M Rosenbruch, P Bringmann, K Kauser
Exp. Hematol., 2018-01-11;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

p16Ink4a and p21Cip1/Waf1 promote tumour growth by enhancing myeloid-derived suppressor cells chemotaxis
Authors: A Okuma, A Hanyu, S Watanabe, E Hara
Nat Commun, 2017-12-12;8(1):2050.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Vasopressin stimulates the proliferation and differentiation of red blood cell precursors and improves recovery from anemia
Authors: Balázs Mayer, Krisztián Németh, Miklós Krepuska, Vamsee D. Myneni, Dragan Maric, John F. Tisdale et al.
Science Translational Medicine

FGF23 expression in rodents is directly induced via erythropoietin after inhibition of hypoxia inducible factor proline hydroxylase
Authors: I Flamme, P Ellinghaus, D Urrego, T Krüger
PLoS ONE, 2017-10-26;12(10):e0186979.
Species: Rat
Sample Types: In Vivo
Applications: Control

Therapeutic Effectiveness of Anti-RAGE Antibody Administration in a Rat Model of Crush Injury
Authors: H Matsumoto, N Matsumoto, J Shimazaki, J Nakagawa, Y Imamura, K Yamakawa, T Yamada, M Ikeda, H Hiraike, H Ogura, T Shimazu
Sci Rep, 2017-09-25;7(1):12255.
Species: Rat
Sample Types: Whole Tissue
Applications: IHC

Sec24C-Dependent Transport of Claudin-1 Regulates Hepatitis C Virus Entry
Authors: Peiqi Yin, Ye Li, Leiliang Zhang
Journal of Virology

Microbiome-mediated neutrophil recruitment via CXCR2 and protection from amebic colitis
Authors: K Watanabe, CA Gilchrist, MJ Uddin, SL Burgess, MM Abhyankar, SN Moonah, Z Noor, JR Donowitz, BN Schneider, T Arju, E Ahmed, M Kabir, M Alam, R Haque, P Pramoonjag, B Mehrad, WA Petri
PLoS Pathog., 2017-08-17;13(8):e1006513.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus
Authors: Y Kannan, LJ Entwistle, VS Pelly, J Perez-Llor, AW Walker, SC Ley, MS Wilson
PLoS Pathog., 2017-07-31;13(7):e1006536.
Species: Mouse
Sample Types: In Vivo

MiR-497?195 cluster regulates angiogenesis during coupling with osteogenesis by maintaining endothelial Notch and HIF-1? activity
Authors: M Yang, CJ Li, X Sun, Q Guo, Y Xiao, T Su, ML Tu, H Peng, Q Lu, Q Liu, HB He, TJ Jiang, MX Lei, M Wan, X Cao, XH Luo
Nat Commun, 2017-07-07;8(0):16003.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

At Term, XmO and XpO Mouse Placentas Show Differences in Glucose Metabolism in the Trophectoderm-Derived Outer Zone
Authors: Nannan He, Shujing J. Lim, Joana C. Moreira de Mello, Injerreau Navarro, Monika Bialecka, Daniela C. F. Salvatori et al.
Frontiers in Cell and Developmental Biology

Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth
Authors: Y Shi, YF Ping, W Zhou, ZC He, C Chen, BS Bian, L Zhang, L Chen, X Lan, XC Zhang, K Zhou, Q Liu, H Long, TW Fu, XN Zhang, MF Cao, Z Huang, X Fang, X Wang, H Feng, XH Yao, SC Yu, YH Cui, X Zhang, JN Rich, S Bao, XW Bian
Nat Commun, 2017-06-01;8(0):15080.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry, Functional Assay

Elucidation of the Role of Lectin-Like oxLDL Receptor-1 in the Metabolic Responses of Macrophages to Human oxLDL
Authors: DW Kimmel, WP Dole, DE Cliffel
J Lipids, 2017-05-31;2017(0):8479482.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

PD-1 Blockade Promotes Emerging Checkpoint Inhibitors in Enhancing T Cell Responses to Allogeneic Dendritic Cells
Authors: C Stecher, C Battin, J Leitner, M Zettl, K Grabmeier-, C Höller, GJ Zlabinger, P Steinberge
Front Immunol, 2017-05-22;8(0):572.
Species: Human
Sample Types: Whole Cells
Applications: Control

Evaluation of F8-TNF-? in Models of Early and Progressive Metastatic Osteosarcoma
Authors: B Robl, SM Botter, A Boro, D Meier, D Neri, B Fuchs
Transl Oncol, 2017-04-25;10(3):419-430.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

Regulatory T cells promote myelin regeneration in the central nervous system
Authors: Y Dombrowski, T O'Hagan, M Dittmer, R Penalva, SR Mayoral, P Bankhead, S Fleville, G Eleftheria, C Zhao, M Naughton, R Hassan, J Moffat, J Falconer, A Boyd, P Hamilton, IV Allen, A Kissenpfen, PN Moynagh, E Evergren, B Perbal, AC Williams, RJ Ingram, JR Chan, RJ Franklin, DC Fitzgerald
Nat. Neurosci, 2017-03-13;0(0):.
Species: Mouse
Sample Types: Whole Tissue

Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Displacement of TLR9
Authors: JA Schwartz, KL Clayton, S Mujib, H Zhang, AK Rahman, J Liu, FY Yue, E Benko, C Kovacs, MA Ostrowski
J. Immunol, 2017-03-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Role of Prolactin in Promotion of Immune Cell Migration into the Mammary Gland
Authors: Riva Dill, Ameae M. Walker
Journal of Mammary Gland Biology and Neoplasia

Role of Eosinophils and Tumor Necrosis Factor Alpha in Interleukin-25-Mediated Protection from Amebic Colitis
Authors: Z Noor, K Watanabe, MM Abhyankar, SL Burgess, EL Buonomo, CA Cowardin, WA Petri
MBio, 2017-02-28;8(1):.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Intestinal commensal bacteria mediate lung mucosal immunity and promote resistance of newborn mice to infection
Authors: J Gray, K Oehrle, G Worthen, T Alenghat, J Whitsett, H Deshmukh
Sci Transl Med, 2017-02-08;9(376):.
Species: Mouse
Sample Types: In Vivo
Applications: Isotype Control

Targeting GM-CSF in epithelial and vascular remodeling in experimental Eosinophilic Esophagitis
Authors: Eóin N McNamee
Allergy, 2017-01-23;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

A TLR9 agonist promotes IL-22-dependent pancreatic islet allograft survival in type 1 diabetic mice
Nat Commun, 2016-12-16;7(0):13896.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry

Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD
Authors: Hoeke A Baarsma
J. Exp. Med, 2016-12-15;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Control

A Herpesviral induction of RAE-1 NKG2D ligand expression occurs through release of HDAC mediated repression
Elife, 2016-11-22;5(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry

Basophils promote tumor rejection via chemotaxis and infiltration of CD8+ T cells
Cancer Res., 2016-11-22;0(0):.
Species: Mouse
Sample Types: In Vivo

The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin
Nat. Immunol., 2016-11-21;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Dietary phosphate supplement does not rescue skeletal phenotype in a mouse model for craniometaphyseal dysplasia
Authors: I-Ping Chen
J Negat Results Biomed, 2016-10-26;15(1):18.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima
Nat Immunol, 2016-09-26;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Tick-borne encephalitis virus induces chemokine RANTES expression via activation of IRF-3 pathway
J Neuroinflammation, 2016-08-30;13(1):209.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Allostimulatory Effects of Dendritic Cells with Characteristic Features of a Regulatory Phenotype
PLoS ONE, 2016-08-15;11(8):e0159986.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay Control, Neutralization Control

Role of Protease-Activated Receptor 2 in the development of lower urinary tract dysfunction
Authors: Kenny Roman, Stephen F. Murphy, Joseph D. Done, Kevin E. McKenna, Anthony J. Schaeffer, Praveen Thumbikat
Journal of Urology

Thymic Stromal Lymphopoietin Neutralization Inhibits the Immune Adjuvant Effect of Di-(2-Ethylhexyl) Phthalate in Balb/c Mouse Asthma Model
PLoS ONE, 2016-07-28;11(7):e0159479.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Deficiency of programmed cell death 4 results in increased IL-10 expression by macrophages and thereby attenuates atherosclerosis in hyperlipidemic mice
Authors: Yang Jiang, Qi Gao, Liyang Wang, Chun Guo, Faliang Zhu, Bo Wang et al.
Cellular & Molecular Immunology

Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair
Authors: Jennifer Quantius
PLoS Pathog, 2016-06-20;12(6):e1005544.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Flow Cytometry

NKG2D-NKG2D Ligand Interaction Inhibits the Outgrowth of Naturally Arising Low-Grade B Cell Lymphoma In Vivo
J Immunol, 2016-05-02;196(11):4805-13.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry

Osteopontin protects against high phosphate-induced nephrocalcinosis and vascular calcification
Authors: Neil J. Paloian, Elizabeth M. Leaf, Cecilia M. Giachelli
Kidney International

IFN-gamma induction by neutrophil-derived IL-17A homodimer augments pulmonary antibacterial defense
Authors: Shanshan Cai, Sanjay Batra, Ingeborg Langohr, Yochiro Iwakura, Samithamby Jeyaseelan
Mucosal Immunology

Seminal plasma induces inflammation in the uterus through the ?? T/IL-17 pathway
Authors: ZH Song, ZY Li, DD Li, WN Fang, HY Liu, DD Yang, CY Meng, Y Yang, JP Peng
Sci Rep, 2016-04-25;6(0):25118.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Neutrophils suppress intraluminal NK-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells
Authors: A Spiegel, MW Brooks, S Houshyar, F Reinhardt, M Ardolino, E Fessler, MB Chen, JA Krall, J DeCock, IK Zervantona, A Iannello, Y Iwamoto, V Cortez-Ret, RD Kamm, MJ Pittet, DH Raulet, RA Weinberg
Cancer Discov, 2016-04-12;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis
Authors: D Schlam, J Canton, M Carreño, H Kopinski, SA Freeman, S Grinstein, GD Fairn
MBio, 2016-04-05;7(2):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry

CD4+CD25+ Regulatory T Cells Inhibit Natural Killer Cell Hepatocytotoxicity of Hepatitis B Virus Transgenic Mice via Membrane-Bound TGF-beta and OX40
Authors: Yongyan Chen, Rui Sun, Xunyao Wu, Min Cheng, Haiming Wei, Zhigang Tian
Journal of Innate Immunity

A protective role for IL-13 receptor alpha 1 in bleomycin-induced pulmonary injury and repair
Authors: D Karo-Atar, A Bordowitz, O Wand, M Pasmanik-Chor, I E Fernandez, M Itan et al.
Mucosal Immunology

CCL22-specific Antibodies Reveal That Engagement of Two Distinct Binding Domains on CCL22 Is Required for CCR4-mediated Function
Authors: Sandra Santulli-Marotto, John Wheeler, Eilyn R. Lacy, Ken Boakye, Jennifer Luongo, Sheng-Jiun Wu et al.
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy

IL-17A Is an Important Effector of the Immune Response of the Mammary Gland to Escherichia coli Infection.
Authors: Porcherie A, Gilbert F, Germon P, Cunha P, Trotereau A, Rossignol C, Winter N, Berthon P, Rainard P
J Immunol, 2015-12-18;196(2):803-12.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization Control

Dendritic Cells Regulate Treg-Th17 Axis in Obstructive Phase of Bile Duct Injury in Murine Biliary Atresia.
Authors: Liu Y, Li K, Yang L, Tang S, Wang X, Cao G, Li S, Lei H, Zhang X
PLoS ONE, 2015-09-01;10(9):e0136214.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization Control

Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy.
Authors: Barreira da Silva R, Laird M, Yatim N, Fiette L, Ingersoll M, Albert M
Nat Immunol, 2015-06-15;16(8):850-8.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain
Authors: Deepitha Selvaraj, Vijayan Gangadharan, Christoph W. Michalski, Martina Kurejova, Sebastian Stösser, Kshitij Srivastava et al.
Cancer Cell

P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy.
Authors: Wang H, Hong L, Huang J, Jiang Q, Tao R, Tan C, Lu N, Wang C, Ahmed M, Lu Y, Liu Z, Shi W, Lai E, Wilcox C, Han F
Cell Res, 2015-05-22;25(6):674-90.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Critical role for IL-18 in spontaneous lung inflammation caused by autophagy deficiency.
Authors: Abdel Fattah E, Bhattacharya A, Herron A, Safdar Z, Eissa N
J Immunol, 2015-04-17;194(11):5407-16.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization Control

Tumor-induced pressure in the bone microenvironment causes osteocytes to promote the growth of prostate cancer bone metastases.
Authors: Sottnik J, Dai J, Zhang H, Campbell B, Keller E
Cancer Res, 2015-04-08;75(11):2151-8.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control

Immune complexes regulate bone metabolism through FcRgamma signalling.
Authors: Negishi-Koga T, Gober H, Sumiya E, Komatsu N, Okamoto K, Sawa S, Suematsu A, Suda T, Sato K, Takai T, Takayanagi H
Nat Commun, 2015-03-31;6(0):6637.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry

Neonatal Streptococcus pneumoniae infection may aggravate adulthood allergic airways disease in association with IL-17A.
Authors: Yang B, Liu R, Yang T, Jiang X, Zhang L, Wang L, Wang Q, Luo Z, Liu E, Fu Z
PLoS ONE, 2015-03-27;10(3):e0123010.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization Control

The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity
Authors: Yasmina Noubia Abdiche, Yik Andy Yeung, Javier Chaparro-Riggers, Ishita Barman, Pavel Strop, Sherman Michael Chin et al.
mAbs

Static stretch affects neural stem cell differentiation in an extracellular matrix-dependent manner.
Authors: Arulmoli J, Pathak M, McDonnell L, Nourse J, Tombola F, Earthman J, Flanagan L
Sci Rep, 2015-02-17;5(0):8499.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

The calcineurin-NFAT axis controls allograft immunity in myeloid-derived suppressor cells through reprogramming T cell differentiation.
Authors: Wang X, Bi Y, Xue L, Liao J, Chen X, Lu Y, Zhang Z, Wang J, Liu H, Yang H, Liu G
Mol Cell Biol, 2014-12-01;35(3):598-609.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Cytokine signaling by grafted neuroectodermal stem cells rescues motoneurons destined to die
Authors: Krisztián Pajer, Georg A. Feichtinger, Gábor Márton, Sonja Sabitzer, Dieter Klein, Heinz Redl et al.
Experimental Neurology

Syndecan-1 in the mouse parietal peritoneum microcirculation in inflammation.
Authors: Kowalewska P, Patrick A, Fox-Robichaud A
PLoS ONE, 2014-09-03;9(9):e104537.
Species: Mouse
Sample Types: In Vivo
Applications: IHC-Fr

Tryptase - PAR2 axis in Experimental Autoimmune Prostatitis, a model for Chronic Pelvic Pain Syndrome
Authors: Kenny Roman, Joseph D. Done, Anthony J. Schaeffer, Stephen F. Murphy, Praveen Thumbikat
Pain

CCR6 is a prognostic marker for overall survival in patients with colorectal cancer, and its overexpression enhances metastasis in vivo.
Authors: Liu, Jinlin, Ke, Fang, Xu, Zhenyao, Liu, Zhaoyuan, Zhang, Lingyun, Yan, Sha, Wang, Zhe, Wang, Hong, Wang, Honglin
PLoS ONE, 2014-06-30;9(6):e101137.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil- and CCL8-dependent manner.
Authors: Dulek D, Newcomb D, Goleniewska K, Cephus J, Zhou W, Reiss S, Toki S, Ye F, Zaynagetdinov R, Sherrill T, Blackwell T, Moore M, Boyd K, Kolls J, Peebles R
Infect Immun, 2014-06-23;82(9):3723-39.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Nitric oxide regulates BAFF expression and T cell-independent antibody responses.
Authors: Giordano D, Draves K, Li C, Hohl T, Clark E
J Immunol, 2014-06-20;193(3):1110-20.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry

gammadelta T cells are required for pulmonary IL-17A expression after ozone exposure in mice: role of TNFalpha.
Authors: Mathews J, Williams A, Brand J, Wurmbrand A, Chen L, Ninin F, Si H, Kasahara D, Shore S
PLoS ONE, 2014-05-13;9(5):e97707.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

NADPH oxidase-independent formation of extracellular DNA traps by basophils.
Authors: Morshed M, Hlushchuk R, Simon D, Walls A, Obata-Ninomiya K, Karasuyama H, Djonov V, Eggel A, Kaufmann T, Simon H, Yousefi S
J Immunol, 2014-04-25;192(11):5314-23.
Species: Mouse
Sample Types: Whole Cells
Applications: Isotype Control

Eosinophils promote generation and maintenance of immunoglobulin-A-expressing plasma cells and contribute to gut immune homeostasis.
Authors: Chu V, Beller A, Rausch S, Strandmark J, Zanker M, Arbach O, Kruglov A, Berek C
Immunity, 2014-04-17;40(4):582-93.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Interleukin-17A modulates circulating tumor cells in tumor draining vein of colorectal cancers and affects metastases.
Authors: Tseng J, Yang C, Liang S, Liu R, Yang S, Lin J, Chen Y, Wu Y, Jiang J, Lin C
Clin Cancer Res, 2014-03-27;20(11):2885-97.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

The role of host and microbial factors in the pathogenesis of pneumococcal bacteraemia arising from a single bacterial cell bottleneck.
Authors: Gerlini A, Colomba L, Furi L, Braccini T, Manso A, Pammolli A, Wang B, Vivi A, Tassini M, Van Rooijen N, Pozzi G, Ricci S, Andrew P, Koedel U, Moxon E, Oggioni M
PLoS Pathog, 2014-03-20;10(3):e1004026.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Flow Cytometry

MULT1E/mIL-12: a novel bifunctional protein for natural killer cell activation.
Authors: Tietje A, Li J, Yu X, Wei Y
Gene Ther, 2014-02-27;21(5):468-75.
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: ELISA Development

mTOR limits the recruitment of CD11b+Gr1+Ly6Chigh myeloid-derived suppressor cells in protecting against murine immunological hepatic injury.
Authors: Zhang Y, Bi Y, Yang H, Chen X, Liu H, Lu Y, Zhang Z, Liao J, Yang S, Chu Y, Yang R, Liu G
J Leukoc Biol, 2014-02-25;95(6):961-70.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice.
Authors: Guabiraba R, Besnard A, Menezes G, Secher T, Jabir M, Amaral S, Braun H, Lima-Junior R, Ribeiro R, Cunha F, Teixeira M, Beyaert R, Graham G, Liew F
Mucosal Immunol, 2014-01-15;7(5):1079-93.
Species: Mouse
Sample Types: In Vivo, Whole Tissue
Applications: Neutralization

IL‐6 controls susceptibility to helminth infection by impeding Th2 responsiveness and altering the Treg phenotype in vivo
Authors: Katherine A. Smith, Rick M. Maizels
European Journal of Immunology

Engagement of two distinct binding domains on CCL17 is required for signaling through CCR4 and establishment of localized inflammatory conditions in the lung.
Authors: Santulli-Marotto S, Boakye K, Lacy E, Wu S, Luongo J, Kavalkovich K, Coelho A, Hogaboam C, Ryan M
PLoS ONE, 2013-12-05;8(12):e81465.
Species: Mouse
Sample Types: Recombinant Protein
Applications: Bioassay

Retinoic acid prevents mesenteric lymph node dendritic cells from inducing IL-13-producing inflammatory Th2 cells.
Authors: Yokota-Nakatsuma A, Takeuchi H, Ohoka Y, Kato C, Song S, Hoshino T, Yagita H, Ohteki T, Iwata M
Mucosal Immunol, 2013-11-13;7(4):786-801.
Species: Mouse
Sample Types: Whole Cells
Applications: Isotype Control

Cholera Toxin Enhances Vaccine-Induced Protection against Mycobacterium Tuberculosis Challenge in Mice
Authors: Kristin L. Griffiths, Elena Stylianou, Hazel C. Poyntz, Gareth J. Betts, Helen A. Fletcher, Helen McShane
PLoS ONE

Surrogate Antibodies That Specifically Bind and Neutralize CCL17 But Not CCL22
Authors: Sandra Santulli-Marotto, Jamie Fisher, Theodore Petley, Ken Boakye, Tadas Panavas, Jennifer Luongo et al.
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
Species: E. coli
Sample Types: Whole Cells
Applications: Neutralization Control

gamma δ T Cells Are Essential Effectors of Type 1 Diabetes in the Nonobese Diabetic Mouse Model
Authors: Janet G. M. Markle, Steve Mortin-Toth, Andrea S. L. Wong, Liping Geng, Adrian Hayday, Jayne S. Danska
The Journal of Immunology

Interleukin-33 and alveolar macrophages contribute to the mechanisms underlying the exacerbation of IgE-mediated airway inflammation and remodelling in mice.
Authors: Mizutani N, Nabe T, Yoshino S
Immunology, 2013-06-01;139(2):205-18.
Species: Mouse
Sample Types: In Vivo
Applications: Isotype Control

Artemin-GFRalpha3 interactions partially contribute to acute inflammatory hypersensitivity.
Authors: Thornton P, Hatcher J, Robinson I, Sargent B, Franzen B, Martino G, Kitching L, Glover C, Anderson D, Forsmo-Bruce H, Low C, Cusdin F, Dosanjh B, Williams W, Steffen A, Thompson S, Eklund M, Lloyd C, Chessell I, Hughes J
Neurosci Lett, 2013-04-19;545(0):23-8.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Differential role of lipocalin 2 during immune complex-mediated acute and chronic inflammation in mice.
Authors: Shashidharamurthy R, Machiah D, Aitken J, Putty K, Srinivasan G, Chassaing B, Parkos C, Selvaraj P, Vijay-Kumar M
Arthritis Rheum, 2013-04-01;65(4):1064-73.
Species: Mouse
Sample Types:

Galectin-9 functionally impairs natural killer cells in humans and mice.
Authors: Golden-Mason L, McMahan R, Strong M, Reisdorph R, Mahaffey S, Palmer B, Cheng L, Kulesza C, Hirashima M, Niki T, Rosen H
J Virol, 2013-02-13;87(9):4835-45.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Neutralization of TSLP Inhibits Airway Remodeling in a Murine Model of Allergic Asthma Induced by Chronic Exposure to House Dust Mite
Authors: Zhuang-Gui Chen, Tian-Tuo Zhang, Hong-Tao Li, Fen-Hua Chen, Xiao-Ling Zou, Jing-Zhi Ji et al.
PLoS ONE

Endoglin Requirement for BMP9 Signaling in Endothelial Cells Reveals New Mechanism of Action for Selective Anti-Endoglin Antibodies
Authors: Olivier Nolan-Stevaux, Wendy Zhong, Stacey Culp, Kathy Shaffer, Joseph Hoover, Dineli Wickramasinghe et al.
PLoS ONE

Respiratory syncytial virus reverses airway hyperresponsiveness to methacholine in ovalbumin-sensitized mice.
Authors: Aeffner F, Davis I
PLoS ONE, 2012-10-02;7(10):e46660.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Inducible IL-33 expression by mast cells is regulated by a calcium-dependent pathway.
Authors: Hsu C, Bryce P
J Immunol, 2012-08-24;189(7):3421-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Control

Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma.
Authors: Blotta, Simona, Jakubikova, Jana, Calimeri, Teresa, Roccaro, Aldo M, Amodio, Nicola, Azab, Abdel Ka, Foresta, Umberto, Mitsiades, Constant, Rossi, Marco, Todoerti, Katia, Molica, Stefano, Morabito, Fortunat, Neri, Antonino, Tagliaferri, Piersand, Tassone, Pierfran, Anderson, Kenneth, Munshi, Nikhil C
Blood, 2012-07-20;120(25):5002-13.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry Control

Regulation of T(H)2 development by CXCR5+ dendritic cells and lymphotoxin-expressing B cells.
Authors: Leon B, Ballesteros-Tato A, Browning JL, Dunn R, Randall TD, Lund FE
Nat. Immunol., 2012-05-27;13(7):681-90.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Pulmonary Inflammation Induced by Subacute Ozone Is Augmented in Adiponectin-Deficient Mice: Role of IL-17A
Authors: David I. Kasahara, Hye Y. Kim, Alison S. Williams, Norah G. Verbout, Jennifer Tran, Huiqing Si et al.
The Journal of Immunology
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo Control

CXCL1 can be regulated by IL-6 and promotes granulocyte adhesion to brain capillaries during bacterial toxin exposure and encephalomyelitis.
Authors: Roy M, Richard JF, Dumas A, Vallieres L
J Neuroinflammation, 2012-01-23;9(0):18.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of coxsackievirus b3-induced viral myocarditis reduces myocardium inflammation
Authors: Yang Fan, Wu Weifeng, Yan Yuluan, Kong Qing, Pang Yu, Huang Yanlan
Virology Journal

Virally induced upregulation of heparan sulfate on B cells Via the action of type-I interferon
Authors: Nadine Jarousse, Damian L. Trujillo, Sarah Wilcox-Adelman, Laurent Coscoy
The Journal of Immunology

IL-23 is required for long-term control of Mycobacterium tuberculosis and B cell follicle formation in the infected lung.
Authors: Khader SA, Guglani L, Rangel-Moreno J
J. Immunol., 2011-10-14;187(10):5402-7.
Species: Mouse
Sample Types: In Vivo
Applications: Control

The ageing systemic milieu negatively regulates neurogenesis and cognitive function.
Authors: Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A, Lucin KM, Czirr E, Park JS, Couillard-Despres S, Aigner L, Li G, Peskind ER, Kaye JA, Quinn JF, Galasko DR, Xie XS, Rando TA, Wyss-Coray T
Nature, 2011-08-31;477(7362):90-4.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Control

TNF-alpha promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines.
Authors: Zhao C, Sardella A, Chun J, Poubelle PE, Fernandes MJ, Bourgoin SG
J. Lipid Res., 2011-04-26;52(7):1307-18.
Species: Mouse
Sample Types: In Vivo
Applications: Control

T Cell-, Interleukin-12-, and Gamma Interferon-Driven Viral Clearance in Measles Virus-Infected Brain Tissue
Authors: Samantha R. Stubblefield Park, Mi Widness, Alan D. Levine, Catherine E. Patterson
Journal of Virology

Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells.
Authors: Islam SA, Chang DS, Colvin RA
Nat. Immunol., 2011-01-09;12(2):167-77.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Dynamic macrophage "probing" is required for the efficient capture of phagocytic targets.
Authors: Flannagan RS, Harrison RE, Yip CM, Jaqaman K, Grinstein S
J. Cell Biol., 2010-12-06;191(6):1205-18.
Species: Mouse
Sample Types:
Applications: Flow Cytometry Control

A critical function of Th17 proinflammatory cells in the development of atherosclerotic plaque in mice.
Authors: Gao Q, Jiang Y, Ma T, Zhu F, Gao F, Zhang P, Guo C, Wang Q, Wang X, Ma C, Zhang Y, Chen W, Zhang L
J. Immunol., 2010-10-15;185(10):5820-7.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Innate immune activation during Salmonella infection initiates extramedullary erythropoiesis and splenomegaly.
Authors: Jackson A, Nanton MR, O'Donnell H
J. Immunol., 2010-10-15;185(10):6198-204.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Molecular immune responses to aerosol challenge with Francisella tularensis in mice inoculated with live vaccine candidates of varying efficacy.
Authors: Shen H, Harris G, Chen W, Sjostedt A, Ryden P, Conlan W
PLoS ONE, 2010-10-12;5(10):e13349.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Patched1 inhibits epidermal progenitor cell expansion and basal cell carcinoma formation by limiting Igfbp2 activity.
Authors: Villani RM, Adolphe C, Palmer J, Waters MJ, Wainwright BJ
Cancer Prev Res (Phila), 2010-09-21;3(10):1222-34.
Species: Mouse
Sample Types: Whole Tissue
Applications: Control

Protective role of interleukin-17 in murine NKT cell-driven acute experimental hepatitis.
Authors: Wondimu Z, Santodomingo-Garzon T, Le T, Swain MG
Am. J. Pathol., 2010-09-16;177(5):2334-46.
Species: Mouse
Sample Types: In Vivo
Applications: Control

IL-33 is produced by mast cells and regulates IgE-dependent inflammation.
Authors: Hsu CL, Neilsen CV, Bryce PJ
PLoS ONE, 2010-08-03;5(8):e11944.
Species: Mouse
Sample Types: Whole Cells
Applications: Control

CXCL13 Blockade Disrupts B Lymphocyte Organization in Tertiary Lymphoid Structures without Altering B Cell Receptor Bias or Preventing Diabetes in Nonobese Diabetic Mice
Authors: Rachel A. Henry, Peggy L. Kendall
The Journal of Immunology

IL-17A-producing gammadelta T and Th17 lymphocytes mediate lung inflammation but not fibrosis in experimental silicosis.
Authors: Lo Re S, Dumoutier L, Couillin I, Van Vyve C, Yakoub Y, Uwambayinema F, Marien B, van den Brule S, Van Snick J, Uyttenhove C, Ryffel B, Renauld JC, Lison D, Huaux F
J. Immunol., 2010-04-26;184(11):6367-77.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Chlamydial respiratory infection during allergen sensitization drives neutrophilic allergic airways disease.
Authors: Horvat JC, Starkey MR, Kim RY, Beagley KW, Preston JA, Gibson PG, Foster PS, Hansbro PM
J. Immunol., 2010-03-12;184(8):4159-69.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Salmonella disrupts lymph node architecture by TLR4-mediated suppression of homeostatic chemokines.
Authors: St John AL, Abraham SN
Nat. Med., 2009-10-25;15(11):1259-65.
Species: Mouse
Sample Types: In Vivo
Applications: Control

IL-17/Th17 promotes type 1 T cell immunity against pulmonary intracellular bacterial infection through modulating dendritic cell function.
Authors: Bai H, Cheng J, Gao X, Joyee AG, Fan Y, Wang S, Jiao L, Yao Z, Yang X
J. Immunol., 2009-10-07;183(9):5886-95.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Encephalitogenicity of complete Freund's adjuvant relative to CpG is linked to induction of Th17 cells.
Authors: Tigno-Aranjuez JT, Jaini R, Tuohy VK, Lehmann PV, Tary-Lehmann M
J. Immunol., 2009-10-07;183(9):5654-61.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Junctional adhesion molecule (JAM)-B supports lymphocyte rolling and adhesion through interaction with alpha4beta1 integrin.
Authors: Ludwig RJ, Hardt K, Hatting M, Bistrian R, Diehl S, Radeke HH, Podda M, Schon MP, Kaufmann R, Henschler R, Pfeilschifter JM, Santoso S, Boehncke WH
Immunology, 2009-10-01;128(2):196-205.
Species: Mouse
Sample Types: In Vivo
Applications: Control

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses.
Authors: Wu S, Rhee KJ, Albesiano E, Rabizadeh S, Wu X, Yen HR, Huso DL, Brancati FL, Wick E, McAllister F, Housseau F, Pardoll DM, Sears CL
Nat. Med., 2009-08-23;15(9):1016-22.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Absence of functional Hfe protects mice from invasive Salmonella enterica serovar Typhimurium infection via induction of lipocalin-2.
Authors: Nairz M, Theurl I, Schroll A, Theurl M, Fritsche G, Lindner E, Seifert M, Crouch ML, Hantke K, Akira S, Fang FC, Weiss G
Blood, 2009-08-21;114(17):3642-51.
Species: Mouse
Sample Types: Serum
Applications: Control

TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia.
Authors: Lagler H, Sharif O, Haslinger I, Matt U, Stich K, Furtner T, Doninger B, Schmid K, Gattringer R, de Vos AF, Knapp S
J. Immunol., 2009-07-13;183(3):2027-36.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Expression of the ULBP ligands for NKG2D by B-NHL cells plays an important role in determining their susceptibility to rituximab-induced ADCC.
Authors: Inagaki A, Ishida T, Yano H, Ishii T, Kusumoto S, Ito A, Ri M, Mori F, Ding J, Komatsu H, Iida S, Ueda R
Int. J. Cancer, 2009-07-01;125(1):212-21.
Species: Human
Sample Types: Whole Cells
Applications: Control

A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum.
Authors: Zhang X, Gao L, Lei L, Zhong Y, Dube P, Berton MT, Arulanandam B, Zhang J, Zhong G
J. Immunol., 2009-06-19;183(2):1291-300.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production.
Authors: Lemos HP, Grespan R, Vieira SM, Cunha TM, Verri WA, Fernandes KS, Souto FO, McInnes IB, Ferreira SH, Liew FY, Cunha FQ
Proc. Natl. Acad. Sci. U.S.A., 2009-03-16;106(14):5954-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Control

A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation.
Authors: Boehme SA, Franz-Bacon K, Chen EP, Sasik R, Sprague LJ, Ly TW, Hardiman G, Bacon KB
Int. Immunol., 2008-12-09;21(1):81-93.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection.
Authors: Bozza S, Zelante T, Moretti S, Bonifazi P, DeLuca A, D'Angelo C, Giovannini G, Garlanda C, Boon L, Bistoni F, Puccetti P, Mantovani A, Romani L
J. Immunol., 2008-03-15;180(6):4022-31.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.
Authors: D'Angelo C, Segal BH
Nature, 2008-01-10;451(7175):211-5.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Keratocan and lumican regulate neutrophil infiltration and corneal clarity in lipopolysaccharide-induced keratitis by direct interaction with CXCL1.
Authors: Carlson EC, Lin M, Liu CY, Kao WW, Perez VL, Pearlman E
J. Biol. Chem., 2007-10-02;282(49):35502-9.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Control

iNKT cells require CCR4 to localize to the airways and to induce airway hyperreactivity.
Authors: Meyer EH, Wurbel MA, Staton TL, Pichavant M, Kan MJ, Savage PB, DeKruyff RH, Butcher EC, Campbell JJ, Umetsu DT
J. Immunol., 2007-10-01;179(7):4661-71.
Species: Mouse
Sample Types: Whole Cells
Applications: Control

Anti-type II collagen antibody accelerates arthritis via CXCR2-expressing cells in IL-1 receptor antagonist-deficient mice.
Authors: Kagari T, Tanaka D, Doi H, Iwakura Y, Shimozato T
Eur. J. Immunol., 2007-10-01;37(10):2753-63.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge.
Authors: He R, Oyoshi MK, Jin H, Geha RS
Proc. Natl. Acad. Sci. U.S.A., 2007-09-24;104(40):15817-22.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Excreted urinary mediators in an animal model of experimental immune nephritis with potential pathogenic significance.
Authors: Wu T, Xie C, Bhaskarabhatla M, Yan M, Leone A, Chen SS, Zhou XJ, Putterman C, Mohan C
Arthritis Rheum., 2007-03-01;56(3):949-59.
Species: Mouse
Sample Types: In Vivo
Applications: Control

IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells.
Authors: Zheng SG, Wang J, Wang P, Gray JD, Horwitz DA
J. Immunol., 2007-02-15;178(4):2018-27.
Species: Mouse
Sample Types: Whole Cells
Applications: Control

TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells.
Authors: Higgins SC, Jarnicki AG, Lavelle EC, Mills KH
J. Immunol., 2006-12-01;177(11):7980-9.
Species: Mouse
Sample Types: In Vivo
Applications: Control

A new RXR agonist, HX630, suppresses intimal hyperplasia in a mouse blood flow cessation model.
Authors: Haraguchi G, Suzuki J, Kosuge H, Ogawa M, Koga N, Muto S, Itai A, Kagechika H, Shudo K, Isobe M
J. Mol. Cell. Cardiol., 2006-09-11;41(5):885-92.
Species: Mouse
Sample Types: Whole Tissue
Applications: Control

Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines.
Authors: Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck LA, Lamkhioued B
Clin. Immunol., 2006-06-16;120(2):220-31.
Species: Human
Sample Types: Whole Cells
Applications: Control

A role for activation-induced cytidine deaminase in the host response against a transforming retrovirus.
Authors: Gourzi P, Leonova T, Papavasiliou FN
Immunity, 2006-06-01;24(6):779-86.
Species: Mouse
Sample Types: Whole Cells
Applications: Control

Cytokine receptor-mediated trafficking of preformed IL-4 in eosinophils identifies an innate immune mechanism of cytokine secretion.
Authors: Spencer LA, Melo RC, Perez SA, Bafford SP, Dvorak AM, Weller PF
Proc. Natl. Acad. Sci. U.S.A., 2006-02-21;103(9):3333-8.
Species: Human
Sample Types: Whole Cells
Applications: Control

Rapid up-regulation of CXC chemokines in the airways after Ag-specific CD4+ T cell activation.
Authors: Knott PG, Gater PR, Dunford PJ, Fuentes ME, Bertrand CP
J. Immunol., 2001-01-15;166(2):1233-40.
Species: Mouse
Sample Types: In Vivo
Applications: Control

M1 macrophages are required for murine cerebral aneurysm formation
Authors: KW Nowicki, K Hosaka, FJ Walch, EW Scott, BL Hoh
J Neurointerv Surg, 2017-02-14;0(0):.

CXC Motif Chemokine 10 Impairs Autophagy and Autolysosome Formation in Non-alcoholic Steatohepatitis
Authors: Zhang X, Wu WK, Xu W et al.
Theranostics.