You are here

Home » IgG2A » Rat IgG2A Isotype Control

Rat IgG2A Isotype Control

  (97 citations)     
Datasheet / CoA / SDS
Detection of Rat IgGControl by Flow Cytometry

Control

View Details
Product Details
Citations (97)
FAQs
Supplemental Products
Reviews
  • Specificity
    Selected for use as rat IgG2A isotype control. In direct ELISAs, does not cross-react with recombinant human (rh) 6Ckine, recombinant mouse (rm) 6Ckine, rhACT II (rhMIP-1 beta ), rhBLC/BCA-1, rmBLC, rmC10, recombinant rat (rr) CINC-1, rrCINC-2 alpha, rrCINC-2 beta, rrCINC-3, rhCK beta 8-1, recombinant viral (rv) CMV UL146, rmCRG-2, rhENA-78, rhEotaxin, rmEotaxin, rhEotaxin 2, rhEotaxin-3, rmEotaxin 2, rhFractalkine, rmFractalkine, rrFractalkine, rhGCP-2, rmGCP-2, rhGRO alpha, rhGRO beta, rhGRO gamma, rhHCC-1, rhHCC-4, rhI-309, rhIL-8, recombinant porcine IL-8, rhIP-10, rhI-TAC, rmJE, rmKC, rhLeukotactin -1, rhLymphytactin, rmLymphotactin, rmMARC, rhMCP-1, rhMCP-2, rhMCP-3, rhMCP-4, rmMCP-5, rvMCV Type 2, rhMDC, rmMDC, rhMIG, rmMIG, rhMIP-1 alpha, rmMIP-1 alpha, rmMIP-1 beta, rmMIP-1 gamma, rhMIP-1δ, rmMIP-2, rhMIP-3 alpha, rrMIP-3 alpha, rhMIP-3 beta, rmMIP-3 alpha, rmMIP-3 beta, rvMIP-I, rvMIP-II, rvMIP-III, rhMPIF-1, rhNAP-2, rhParc, rhRANTES, rmRANTES, rhSDF-1 alpha, rmSDF-1 alpha, rhSDF-1 beta, rhTarc, rmTARC, rmTCA-3, rhTeck, or rmTeck.
  • Source
    Monoclonal Rat IgG2A Clone # 54447
  • Purification
    Protein A or G purified from hybridoma culture supernatant
  • Immunogen
    KLH
  • Formulation
    Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
  • Endotoxin Level
    <0.10 EU per 1 μg of the antibody by the LAL method.
  • Label
    Unconjugated
Product Datasheets
Product Datasheet

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Certificate of Analysis Lookup

Certificate of Analysis Request Form

To download a Certificate of Analysis, please enter the catalog and lot numbers in the search box below.

Note: Certificate of Analysis not available for kit components.

SDS
Applications
  •  
    Recommended
    Concentration
    Sample
  • Control
    Negative control for use in conjunction with R&D Systems antibodies. Use at the same concentration as the detection antibody.
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Example
Control
Control Rat IgG2a Isotype Control (54447) [Unconjugated]
click image to view larger
Detection of Rat IgGControl by Flow Cytometry B16-F1 mouse melanoma cell line was stained with RatAnti-Mouse Integrin  beta 1/CD29 Monoclonal Antibody (Catalog # MAB2405,filled histogram) or Rat IgG Isotype Control Antibody (Catalog #MAB006,open histogram), followed by Phycoerythrin-conjugated Anti-Rat IgG SecondaryAntibody
(Catalog # F0105B).
Preparation and Storage
  • Reconstitution
    Reconstitute at 0.5 mg/mL in sterile PBS.
  • Shipping
    The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    • 12 months from date of receipt, -20 to -70 °C as supplied.
    • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
    • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: IgG2A

R&D Systems offers a range of secondary antibodies and controls for flow cytometry, immunohistochemistry, and Western blotting. We provide species-specific secondary antibodies that are available with a variety of conjugated labels.

Our NorthernLights fluorescent secondary antibodies are bright and resistant to photobleaching. We are currently offering secondary antibodies recognizing mouse, rat, goat, sheep, and rabbit IgG as well as chicken IgY. These reagents are available with three distinct excitation and emission maxima, making them ideal for multi-color fluorescence microscopy.

  • Long Name:
    Immunoglobulin G2A Fc
  • Alternate Names:
    IgG2A
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

97 Citations: Showing 1 - 10
Filter your results:

Species
 Applications
 Sample Type
  1. Regulation of T(H)2 development by CXCR5+ dendritic cells and lymphotoxin-expressing B cells.
    Authors: Leon B, Ballesteros-Tato A, Browning JL, Dunn R, Randall TD, Lund FE
    Nat. Immunol., 2102;13(7):681-90.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  2. Estrogen Deficiency Promotes Cerebral Aneurysm Rupture by Upregulation of Th17 Cells and Interleukin-17A Which Downregulates E-Cadherin
    Authors: BL Hoh, K Rojas, L Lin, HZ Fazal, S Hourani, KW Nowicki, MB Schneider, K Hosaka
    J Am Heart Assoc, 2018;7(8):.
    Species: Mouse
    Sample Type: In Vivo
    Application: In vivo
  3. TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus
    Authors: Y Kannan, LJ Entwistle, VS Pelly, J Perez-Llor, AW Walker, SC Ley, MS Wilson
    PLoS Pathog., 2017;13(7):e1006536.
    Species: Mouse
    Sample Type: In Vivo
  4. Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth
    Authors: Y Shi, YF Ping, W Zhou, ZC He, C Chen, BS Bian, L Zhang, L Chen, X Lan, XC Zhang, K Zhou, Q Liu, H Long, TW Fu, XN Zhang, MF Cao, Z Huang, X Fang, X Wang, H Feng, XH Yao, SC Yu, YH Cui, X Zhang, JN Rich, S Bao, XW Bian
    Nat Commun, 2017;8(0):15080.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  5. Role of Eosinophils and Tumor Necrosis Factor Alpha in Interleukin-25-Mediated Protection from Amebic Colitis
    Authors: Z Noor, K Watanabe, MM Abhyankar, SL Burgess, EL Buonomo, CA Cowardin, WA Petri
    MBio, 2017;8(1):.
    Species: Mouse
    Sample Type: In Vivo
    Application: In vivo
  6. Evaluation of F8-TNF-? in Models of Early and Progressive Metastatic Osteosarcoma
    Authors: B Robl, SM Botter, A Boro, D Meier, D Neri, B Fuchs
    Transl Oncol, 2017;10(3):419-430.
    Species: Mouse
    Sample Type: Whole Tissue
    Application: IHC OCT-embedded
  7. Regulatory T cells promote myelin regeneration in the central nervous system
    Authors: Y Dombrowski, T O'Hagan, M Dittmer, R Penalva, SR Mayoral, P Bankhead, S Fleville, G Eleftheria, C Zhao, M Naughton, R Hassan, J Moffat, J Falconer, A Boyd, P Hamilton, IV Allen, A Kissenpfen, PN Moynagh, E Evergren, B Perbal, AC Williams, RJ Ingram, JR Chan, RJ Franklin, DC Fitzgerald
    Nat. Neurosci, 2017;0(0):.
    Species: Mouse
    Sample Type: Whole Tissue
  8. Microbiome-mediated neutrophil recruitment via CXCR2 and protection from amebic colitis
    Authors: K Watanabe, CA Gilchrist, MJ Uddin, SL Burgess, MM Abhyankar, SN Moonah, Z Noor, JR Donowitz, BN Schneider, T Arju, E Ahmed, M Kabir, M Alam, R Haque, P Pramoonjag, B Mehrad, WA Petri
    PLoS Pathog., 2017;13(8):e1006513.
    Species: Mouse
    Sample Type: In Vivo
    Application: Neut
  9. Therapeutic Effectiveness of Anti-RAGE Antibody Administration in a Rat Model of Crush Injury
    Authors: H Matsumoto, N Matsumoto, J Shimazaki, J Nakagawa, Y Imamura, K Yamakawa, T Yamada, M Ikeda, H Hiraike, H Ogura, T Shimazu
    Sci Rep, 2017;7(1):12255.
    Species: Rat
    Sample Type: Whole Tissue
    Application: IHC
  10. MiR-497?195 cluster regulates angiogenesis during coupling with osteogenesis by maintaining endothelial Notch and HIF-1? activity
    Authors: M Yang, CJ Li, X Sun, Q Guo, Y Xiao, T Su, ML Tu, H Peng, Q Lu, Q Liu, HB He, TJ Jiang, MX Lei, M Wan, X Cao, XH Luo
    Nat Commun, 2017;8(0):16003.
    Species: Mouse
    Sample Type: Whole Tissue
    Application: IHC
  11. FGF23 expression in rodents is directly induced via erythropoietin after inhibition of hypoxia inducible factor proline hydroxylase
    Authors: I Flamme, P Ellinghaus, D Urrego, T Krüger
    PLoS ONE, 2017;12(10):e0186979.
    Species: Rat
    Sample Type: In Vivo
    Application: Ctrl
  12. p16Ink4a and p21Cip1/Waf1 promote tumour growth by enhancing myeloid-derived suppressor cells chemotaxis
    Authors: A Okuma, A Hanyu, S Watanabe, E Hara
    Nat Commun, 2017;8(1):2050.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  13. Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Displacement of TLR9
    Authors: JA Schwartz, KL Clayton, S Mujib, H Zhang, AK Rahman, J Liu, FY Yue, E Benko, C Kovacs, MA Ostrowski
    J. Immunol, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Neut
  14. Neutrophils suppress intraluminal NK-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells
    Authors: A Spiegel, MW Brooks, S Houshyar, F Reinhardt, M Ardolino, E Fessler, MB Chen, JA Krall, J DeCock, IK Zervantona, A Iannello, Y Iwamoto, V Cortez-Ret, RD Kamm, MJ Pittet, DH Raulet, RA Weinberg
    Cancer Discov, 2016;0(0):.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  15. Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair
    Authors: Jennifer Quantius
    PLoS Pathog, 2016;12(6):e1005544.
    Species: Mouse
    Sample Type: Tissue Homogenates
    Application: Flow
  16. NKG2D-NKG2D Ligand Interaction Inhibits the Outgrowth of Naturally Arising Low-Grade B Cell Lymphoma In Vivo
    J Immunol, 2016;196(11):4805-13.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Flow
  17. Seminal plasma induces inflammation in the uterus through the ?? T/IL-17 pathway
    Authors: ZH Song, ZY Li, DD Li, WN Fang, HY Liu, DD Yang, CY Meng, Y Yang, JP Peng
    Sci Rep, 2016;6(0):25118.
    Species: Mouse
    Sample Type: In Vivo
    Application: In vivo
  18. Dietary phosphate supplement does not rescue skeletal phenotype in a mouse model for craniometaphyseal dysplasia
    Authors: I-Ping Chen
    J Negat Results Biomed, 2016;15(1):18.
    Species: Mouse
    Sample Type: Whole Tissue
    Application: IHC
  19. Thymic Stromal Lymphopoietin Neutralization Inhibits the Immune Adjuvant Effect of Di-(2-Ethylhexyl) Phthalate in Balb/c Mouse Asthma Model
    PLoS ONE, 2016;11(7):e0159479.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  20. CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima
    Nat Immunol, 2016;0(0):.
    Species: Mouse
    Sample Type: In Vivo
    Application: Neut
  21. Allostimulatory Effects of Dendritic Cells with Characteristic Features of a Regulatory Phenotype
    PLoS ONE, 2016;11(8):e0159986.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay Ctrl
  22. IL-17A Is an Important Effector of the Immune Response of the Mammary Gland to Escherichia coli Infection.
    Authors: Porcherie A, Gilbert F, Germon P, Cunha P, Trotereau A, Rossignol C, Winter N, Berthon P, Rainard P
    J Immunol, 2016;196(2):803-12.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Neut Ctrl
  23. Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis
    Authors: D Schlam, J Canton, M Carreño, H Kopinski, SA Freeman, S Grinstein, GD Fairn
    MBio, 2016;7(2):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Flow
  24. A Herpesviral induction of RAE-1 NKG2D ligand expression occurs through release of HDAC mediated repression
    Elife, 2016;5(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Flow
  25. Tick-borne encephalitis virus induces chemokine RANTES expression via activation of IRF-3 pathway
    J Neuroinflammation, 2016;13(1):209.
    Species: Mouse
    Sample Type: In Vivo
    Application: In vivo control
  26. Basophils promote tumor rejection via chemotaxis and infiltration of CD8+ T cells
    Cancer Res., 2016;0(0):.
    Species: Mouse
    Sample Type: In Vivo
  27. The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin
    Nat. Immunol., 2016;0(0):.
    Species: Mouse
    Sample Type: In Vivo
    Application: In vivo
  28. A TLR9 agonist promotes IL-22-dependent pancreatic islet allograft survival in type 1 diabetic mice
    Nat Commun, 2016;7(0):13896.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Flow
  29. Targeting GM-CSF in epithelial and vascular remodeling in experimental Eosinophilic Esophagitis
    Authors: Eóin N McNamee
    Allergy, 2016;0(0):.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  30. Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD
    Authors: Hoeke A Baarsma
    J. Exp. Med, 2016;0(0):.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  31. Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy.
    Authors: Barreira da Silva R, Laird M, Yatim N, Fiette L, Ingersoll M, Albert M
    Nat Immunol, 2015;16(8):850-8.
    Species: Mouse
    Sample Type: In Vivo
    Application: Neut
  32. Static stretch affects neural stem cell differentiation in an extracellular matrix-dependent manner.
    Authors: Arulmoli J, Pathak M, McDonnell L, Nourse J, Tombola F, Earthman J, Flanagan L
    Sci Rep, 2015;5(0):8499.
  33. The calcineurin-NFAT axis controls allograft immunity in myeloid-derived suppressor cells through reprogramming T cell differentiation.
    Authors: Wang X, Bi Y, Xue L, Liao J, Chen X, Lu Y, Zhang Z, Wang J, Liu H, Yang H, Liu G
    Mol Cell Biol, 2015;35(3):598-609.
    Species: Mouse
    Sample Type: In Vivo
    Application: Neut
  34. Immune complexes regulate bone metabolism through FcRgamma signalling.
    Authors: Negishi-Koga T, Gober H, Sumiya E, Komatsu N, Okamoto K, Sawa S, Suematsu A, Suda T, Sato K, Takai T, Takayanagi H
    Nat Commun, 2015;6(0):6637.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Flow
  35. Dendritic Cells Regulate Treg-Th17 Axis in Obstructive Phase of Bile Duct Injury in Murine Biliary Atresia.
    Authors: Liu Y, Li K, Yang L, Tang S, Wang X, Cao G, Li S, Lei H, Zhang X
    PLoS ONE, 2015;10(9):e0136214.
    Species: Mouse
    Sample Type: In Vivo
    Application: Neut Ctrl
  36. Tumor-induced pressure in the bone microenvironment causes osteocytes to promote the growth of prostate cancer bone metastases.
    Authors: Sottnik J, Dai J, Zhang H, Campbell B, Keller E
    Cancer Res, 2015;75(11):2151-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Neut Ctrl
  37. Neonatal Streptococcus pneumoniae infection may aggravate adulthood allergic airways disease in association with IL-17A.
    Authors: Yang B, Liu R, Yang T, Jiang X, Zhang L, Wang L, Wang Q, Luo Z, Liu E, Fu Z
    PLoS ONE, 2015;10(3):e0123010.
    Species: Mouse
    Sample Type: In Vivo
    Application: Neut Ctrl
  38. Critical role for IL-18 in spontaneous lung inflammation caused by autophagy deficiency.
    Authors: Abdel Fattah E, Bhattacharya A, Herron A, Safdar Z, Eissa N
    J Immunol, 2015;194(11):5407-16.
    Species: Mouse
    Sample Type: In Vivo
    Application: Neut Ctrl
  39. NADPH oxidase-independent formation of extracellular DNA traps by basophils.
    Authors: Morshed M, Hlushchuk R, Simon D, Walls A, Obata-Ninomiya K, Karasuyama H, Djonov V, Eggel A, Kaufmann T, Simon H, Yousefi S
    J Immunol, 2014;192(11):5314-23.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Isotype control
  40. Eosinophils promote generation and maintenance of immunoglobulin-A-expressing plasma cells and contribute to gut immune homeostasis.
    Authors: Chu V, Beller A, Rausch S, Strandmark J, Zanker M, Arbach O, Kruglov A, Berek C
    Immunity, 2014;40(4):582-93.
    Species: Mouse
    Sample Type: In Vivo
    Application: In vivo
  41. Nitric oxide regulates BAFF expression and T cell-independent antibody responses.
    Authors: Giordano D, Draves K, Li C, Hohl T, Clark E
    J Immunol, 2014;193(3):1110-20.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Flow
  42. gammadelta T cells are required for pulmonary IL-17A expression after ozone exposure in mice: role of TNFalpha.
    Authors: Mathews J, Williams A, Brand J, Wurmbrand A, Chen L, Ninin F, Si H, Kasahara D, Shore S
    PLoS ONE, 2014;9(5):e97707.
    Species: Mouse
    Sample Type: In Vivo
    Application: In vivo
  43. Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil- and CCL8-dependent manner.
    Authors: Dulek D, Newcomb D, Goleniewska K, Cephus J, Zhou W, Reiss S, Toki S, Ye F, Zaynagetdinov R, Sherrill T, Blackwell T, Moore M, Boyd K, Kolls J, Peebles R
    Infect Immun, 2014;82(9):3723-39.
    Species: Mouse
    Sample Type: In Vivo
    Application: In vivo
  44. Retinoic acid prevents mesenteric lymph node dendritic cells from inducing IL-13-producing inflammatory Th2 cells.
    Authors: Yokota-Nakatsuma A, Takeuchi H, Ohoka Y, Kato C, Song S, Hoshino T, Yagita H, Ohteki T, Iwata M
    Mucosal Immunol, 2014;7(4):786-801.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Isotype control
  45. IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice.
    Authors: Guabiraba R, Besnard A, Menezes G, Secher T, Jabir M, Amaral S, Braun H, Lima-Junior R, Ribeiro R, Cunha F, Teixeira M, Beyaert R, Graham G, Liew F
    Mucosal Immunol, 2014;7(5):1079-93.
    Species: Mouse
    Sample Type: In Vivo
    Application: In vivo
  46. MULT1E/mIL-12: a novel bifunctional protein for natural killer cell activation.
    Authors: Tietje A, Li J, Yu X, Wei Y
    Gene Ther, 2014;21(5):468-75.
    Species: Mouse
    Sample Type: Cell Culture Supernates
    Application: ELISA Development
  47. CCR6 is a prognostic marker for overall survival in patients with colorectal cancer, and its overexpression enhances metastasis in vivo.
    Authors: Liu, Jinlin, Ke, Fang, Xu, Zhenyao, Liu, Zhaoyuan, Zhang, Lingyun, Yan, Sha, Wang, Zhe, Wang, Hong, Wang, Honglin
    PLoS ONE, 2014;9(6):e101137.
    Species: Mouse
    Sample Type: In Vivo
    Application: In vivo
  48. The role of host and microbial factors in the pathogenesis of pneumococcal bacteraemia arising from a single bacterial cell bottleneck.
    Authors: Gerlini A, Colomba L, Furi L, Braccini T, Manso A, Pammolli A, Wang B, Vivi A, Tassini M, Van Rooijen N, Pozzi G, Ricci S, Andrew P, Koedel U, Moxon E, Oggioni M
    PLoS Pathog, 2014;10(3):e1004026.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Flow
  49. mTOR limits the recruitment of CD11b+Gr1+Ly6Chigh myeloid-derived suppressor cells in protecting against murine immunological hepatic injury.
    Authors: Zhang Y, Bi Y, Yang H, Chen X, Liu H, Lu Y, Zhang Z, Liao J, Yang S, Chu Y, Yang R, Liu G
    J Leukoc Biol, 2014;95(6):961-70.
    Species: Mouse
    Sample Type: In Vivo
    Application: In vivo
  50. Syndecan-1 in the mouse parietal peritoneum microcirculation in inflammation.
    Authors: Kowalewska P, Patrick A, Fox-Robichaud A
    PLoS ONE, 2014;9(9):e104537.
    Species: Mouse
    Sample Type: In Vivo
    Application: IHC Fresh
  51. Interleukin-17A modulates circulating tumor cells in tumor draining vein of colorectal cancers and affects metastases.
    Authors: Tseng J, Yang C, Liang S, Liu R, Yang S, Lin J, Chen Y, Wu Y, Jiang J, Lin C
    Clin Cancer Res, 2014;20(11):2885-97.
    Species: Mouse
    Sample Type: In Vivo
    Application: In vivo
  52. Interleukin-33 and alveolar macrophages contribute to the mechanisms underlying the exacerbation of IgE-mediated airway inflammation and remodelling in mice.
    Authors: Mizutani N, Nabe T, Yoshino S
    Immunology, 2013;139(2):205-18.
    Species: Mouse
    Sample Type: In Vivo
    Application: Isotype control
  53. Differential role of lipocalin 2 during immune complex-mediated acute and chronic inflammation in mice.
    Authors: Shashidharamurthy R, Machiah D, Aitken J, Putty K, Srinivasan G, Chassaing B, Parkos C, Selvaraj P, Vijay-Kumar M
    Arthritis Rheum, 2013;65(4):1064-73.
    Species: Mouse
    Sample Type:
  54. Engagement of two distinct binding domains on CCL17 is required for signaling through CCR4 and establishment of localized inflammatory conditions in the lung.
    Authors: Santulli-Marotto S, Boakye K, Lacy E, Wu S, Luongo J, Kavalkovich K, Coelho A, Hogaboam C, Ryan M
    PLoS ONE, 2013;8(12):e81465.
    Species: Mouse
    Sample Type: Recombinant Protein
    Application: Bioassay
  55. Galectin-9 functionally impairs natural killer cells in humans and mice.
    Authors: Golden-Mason L, McMahan R, Strong M, Reisdorph R, Mahaffey S, Palmer B, Cheng L, Kulesza C, Hirashima M, Niki T, Rosen H
    J Virol, 2013;87(9):4835-45.
    Species: Human
    Sample Type: Whole Cells
    Application: Neut
  56. Respiratory syncytial virus reverses airway hyperresponsiveness to methacholine in ovalbumin-sensitized mice.
    Authors: Aeffner F, Davis I
    PLoS ONE, 2012;7(10):e46660.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  57. Inducible IL-33 expression by mast cells is regulated by a calcium-dependent pathway.
    Authors: Hsu C, Bryce P
    J Immunol, 2012;189(7):3421-9.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Ctrl
  58. CXCL1 can be regulated by IL-6 and promotes granulocyte adhesion to brain capillaries during bacterial toxin exposure and encephalomyelitis.
    Authors: Roy M, Richard JF, Dumas A, Vallieres L
    J Neuroinflammation, 2012;9(0):18.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  59. Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma.
    Authors: Blotta, Simona, Jakubikova, Jana, Calimeri, Teresa, Roccaro, Aldo M, Amodio, Nicola, Azab, Abdel Ka, Foresta, Umberto, Mitsiades, Constant, Rossi, Marco, Todoerti, Katia, Molica, Stefano, Morabito, Fortunat, Neri, Antonino, Tagliaferri, Piersand, Tassone, Pierfran, Anderson, Kenneth, Munshi, Nikhil C
    Blood, 2012;120(25):5002-13.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow control
  60. TNF-alpha promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines.
    Authors: Zhao C, Sardella A, Chun J, Poubelle PE, Fernandes MJ, Bourgoin SG
    J. Lipid Res., 2011;52(7):1307-18.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  61. The ageing systemic milieu negatively regulates neurogenesis and cognitive function.
    Authors: Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A, Lucin KM, Czirr E, Park JS, Couillard-Despres S, Aigner L, Li G, Peskind ER, Kaye JA, Quinn JF, Galasko DR, Xie XS, Rando TA, Wyss-Coray T
    Nature, 2011;477(7362):90-4.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  62. IL-23 is required for long-term control of Mycobacterium tuberculosis and B cell follicle formation in the infected lung.
    Authors: Khader SA, Guglani L, Rangel-Moreno J
    J. Immunol., 2011;187(10):5402-7.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  63. Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells.
    Authors: Islam SA, Chang DS, Colvin RA
    Nat. Immunol., 2011;12(2):167-77.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  64. Innate immune activation during Salmonella infection initiates extramedullary erythropoiesis and splenomegaly.
    Authors: Jackson A, Nanton MR, O'Donnell H
    J. Immunol., 2010;185(10):6198-204.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  65. Dynamic macrophage "probing" is required for the efficient capture of phagocytic targets.
    Authors: Flannagan RS, Harrison RE, Yip CM, Jaqaman K, Grinstein S
    J. Cell Biol., 2010;191(6):1205-18.
    Species: Mouse
    Sample Type:
    Application: Flow control
  66. IL-17A-producing gammadelta T and Th17 lymphocytes mediate lung inflammation but not fibrosis in experimental silicosis.
    Authors: Lo Re S, Dumoutier L, Couillin I, Van Vyve C, Yakoub Y, Uwambayinema F, Marien B, van den Brule S, Van Snick J, Uyttenhove C, Ryffel B, Renauld JC, Lison D, Huaux F
    J. Immunol., 2010;184(11):6367-77.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  67. IL-33 is produced by mast cells and regulates IgE-dependent inflammation.
    Authors: Hsu CL, Neilsen CV, Bryce PJ
    PLoS ONE, 2010;5(8):e11944.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Ctrl
  68. Patched1 inhibits epidermal progenitor cell expansion and basal cell carcinoma formation by limiting Igfbp2 activity.
    Authors: Villani RM, Adolphe C, Palmer J, Waters MJ, Wainwright BJ
    Cancer Prev Res (Phila), 2010;3(10):1222-34.
    Species: Mouse
    Sample Type: Whole Tissue
    Application: Ctrl
  69. A critical function of Th17 proinflammatory cells in the development of atherosclerotic plaque in mice.
    Authors: Gao Q, Jiang Y, Ma T, Zhu F, Gao F, Zhang P, Guo C, Wang Q, Wang X, Ma C, Zhang Y, Chen W, Zhang L
    J. Immunol., 2010;185(10):5820-7.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  70. Protective role of interleukin-17 in murine NKT cell-driven acute experimental hepatitis.
    Authors: Wondimu Z, Santodomingo-Garzon T, Le T, Swain MG
    Am. J. Pathol., 2010;177(5):2334-46.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  71. Molecular immune responses to aerosol challenge with Francisella tularensis in mice inoculated with live vaccine candidates of varying efficacy.
    Authors: Shen H, Harris G, Chen W, Sjostedt A, Ryden P, Conlan W
    PLoS ONE, 2010;5(10):e13349.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  72. Chlamydial respiratory infection during allergen sensitization drives neutrophilic allergic airways disease.
    Authors: Horvat JC, Starkey MR, Kim RY, Beagley KW, Preston JA, Gibson PG, Foster PS, Hansbro PM
    J. Immunol., 2010;184(8):4159-69.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  73. Expression of the ULBP ligands for NKG2D by B-NHL cells plays an important role in determining their susceptibility to rituximab-induced ADCC.
    Authors: Inagaki A, Ishida T, Yano H, Ishii T, Kusumoto S, Ito A, Ri M, Mori F, Ding J, Komatsu H, Iida S, Ueda R
    Int. J. Cancer, 2009;125(1):212-21.
  74. A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum.
    Authors: Zhang X, Gao L, Lei L, Zhong Y, Dube P, Berton MT, Arulanandam B, Zhang J, Zhong G
    J. Immunol., 2009;183(2):1291-300.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  75. Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production.
    Authors: Lemos HP, Grespan R, Vieira SM, Cunha TM, Verri WA, Fernandes KS, Souto FO, McInnes IB, Ferreira SH, Liew FY, Cunha FQ
    Proc. Natl. Acad. Sci. U.S.A., 2009;106(14):5954-9.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Ctrl
  76. Encephalitogenicity of complete Freund's adjuvant relative to CpG is linked to induction of Th17 cells.
    Authors: Tigno-Aranjuez JT, Jaini R, Tuohy VK, Lehmann PV, Tary-Lehmann M
    J. Immunol., 2009;183(9):5654-61.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  77. A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation.
    Authors: Boehme SA, Franz-Bacon K, Chen EP, Sasik R, Sprague LJ, Ly TW, Hardiman G, Bacon KB
    Int. Immunol., 2009;21(1):81-93.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  78. IL-17/Th17 promotes type 1 T cell immunity against pulmonary intracellular bacterial infection through modulating dendritic cell function.
    Authors: Bai H, Cheng J, Gao X, Joyee AG, Fan Y, Wang S, Jiao L, Yao Z, Yang X
    J. Immunol., 2009;183(9):5886-95.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  79. Absence of functional Hfe protects mice from invasive Salmonella enterica serovar Typhimurium infection via induction of lipocalin-2.
    Authors: Nairz M, Theurl I, Schroll A, Theurl M, Fritsche G, Lindner E, Seifert M, Crouch ML, Hantke K, Akira S, Fang FC, Weiss G
    Blood, 2009;114(17):3642-51.
    Species: Mouse
    Sample Type: Serum
    Application: Ctrl
  80. Junctional adhesion molecule (JAM)-B supports lymphocyte rolling and adhesion through interaction with alpha4beta1 integrin.
    Authors: Ludwig RJ, Hardt K, Hatting M, Bistrian R, Diehl S, Radeke HH, Podda M, Schon MP, Kaufmann R, Henschler R, Pfeilschifter JM, Santoso S, Boehncke WH
    Immunology, 2009;128(2):196-205.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  81. TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia.
    Authors: Lagler H, Sharif O, Haslinger I, Matt U, Stich K, Furtner T, Doninger B, Schmid K, Gattringer R, de Vos AF, Knapp S
    J. Immunol., 2009;183(3):2027-36.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  82. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses.
    Authors: Wu S, Rhee KJ, Albesiano E, Rabizadeh S, Wu X, Yen HR, Huso DL, Brancati FL, Wick E, McAllister F, Housseau F, Pardoll DM, Sears CL
    Nat. Med., 2009;15(9):1016-22.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  83. Salmonella disrupts lymph node architecture by TLR4-mediated suppression of homeostatic chemokines.
    Authors: St John AL, Abraham SN
    Nat. Med., 2009;15(11):1259-65.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  84. Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.
    Authors: D'Angelo C, Segal BH
    Nature, 2008;451(7175):211-5.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  85. Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection.
    Authors: Bozza S, Zelante T, Moretti S, Bonifazi P, DeLuca A, D'Angelo C, Giovannini G, Garlanda C, Boon L, Bistoni F, Puccetti P, Mantovani A, Romani L
    J. Immunol., 2008;180(6):4022-31.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  86. Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge.
    Authors: He R, Oyoshi MK, Jin H, Geha RS
    Proc. Natl. Acad. Sci. U.S.A., 2007;104(40):15817-22.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  87. iNKT cells require CCR4 to localize to the airways and to induce airway hyperreactivity.
    Authors: Meyer EH, Wurbel MA, Staton TL, Pichavant M, Kan MJ, Savage PB, DeKruyff RH, Butcher EC, Campbell JJ, Umetsu DT
    J. Immunol., 2007;179(7):4661-71.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Ctrl
  88. Excreted urinary mediators in an animal model of experimental immune nephritis with potential pathogenic significance.
    Authors: Wu T, Xie C, Bhaskarabhatla M, Yan M, Leone A, Chen SS, Zhou XJ, Putterman C, Mohan C
    Arthritis Rheum., 2007;56(3):949-59.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  89. Anti-type II collagen antibody accelerates arthritis via CXCR2-expressing cells in IL-1 receptor antagonist-deficient mice.
    Authors: Kagari T, Tanaka D, Doi H, Iwakura Y, Shimozato T
    Eur. J. Immunol., 2007;37(10):2753-63.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  90. IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells.
    Authors: Zheng SG, Wang J, Wang P, Gray JD, Horwitz DA
    J. Immunol., 2007;178(4):2018-27.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Ctrl
  91. Keratocan and lumican regulate neutrophil infiltration and corneal clarity in lipopolysaccharide-induced keratitis by direct interaction with CXCL1.
    Authors: Carlson EC, Lin M, Liu CY, Kao WW, Perez VL, Pearlman E
    J. Biol. Chem., 2007;282(49):35502-9.
    Species: Mouse
    Sample Type: Tissue Homogenates
    Application: Ctrl
  92. Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines.
    Authors: Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck LA, Lamkhioued B
    Clin. Immunol., 2006;120(2):220-31.
  93. Cytokine receptor-mediated trafficking of preformed IL-4 in eosinophils identifies an innate immune mechanism of cytokine secretion.
    Authors: Spencer LA, Melo RC, Perez SA, Bafford SP, Dvorak AM, Weller PF
    Proc. Natl. Acad. Sci. U.S.A., 2006;103(9):3333-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Ctrl
  94. A role for activation-induced cytidine deaminase in the host response against a transforming retrovirus.
    Authors: Gourzi P, Leonova T, Papavasiliou FN
    Immunity, 2006;24(6):779-86.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Ctrl
  95. A new RXR agonist, HX630, suppresses intimal hyperplasia in a mouse blood flow cessation model.
    Authors: Haraguchi G, Suzuki J, Kosuge H, Ogawa M, Koga N, Muto S, Itai A, Kagechika H, Shudo K, Isobe M
    J. Mol. Cell. Cardiol., 2006;41(5):885-92.
    Species: Mouse
    Sample Type: Whole Tissue
    Application: Ctrl
  96. TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells.
    Authors: Higgins SC, Jarnicki AG, Lavelle EC, Mills KH
    J. Immunol., 2006;177(11):7980-9.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
  97. Rapid up-regulation of CXC chemokines in the airways after Ag-specific CD4+ T cell activation.
    Authors: Knott PG, Gater PR, Dunford PJ, Fuentes ME, Bertrand CP
    J. Immunol., 2001;166(2):1233-40.
    Species: Mouse
    Sample Type: In Vivo
    Application: Ctrl
Expand to show all Citations

FAQs

No product specific FAQs exist for this product, however you may

View all Isotype Control FAQs
Isotype Controls
Description Application Cat# Citations Images  

Rat IgG2A PE-conjugated Antibody

 Ctrl IC006P 16  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Rat IgG2A Allophycocyanin Isotype Control

 Ctrl IC006A 8  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Rat IgG2A Alexa Fluor® 488‑conjugated Isotype Control

 Ctrl IC006G  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Rat IgG2A Fluorescein-conjugated Antibody

 Ctrl IC006F 2  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Rat IgG2A Alexa Fluor® 647-conjugated Antibody

 Ctrl IC006R
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Rat IgG2A Alexa Fluor® 700-conjugated Antibody

 Ctrl IC006N
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Rat IgG2A Isotype Control

 Ctrl MAB006R  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Rat IgG2A Biotinylated Isotype Control

 Ctrl IC006B
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Rat IgG2A Alexa Fluor® 405-conjugated Antibody

 Ctrl IC006V
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Rat IgG2A Alexa Fluor® 750-conjugated Antibody

 Ctrl IC006S
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Rat IgG2A Alexa Fluor® 594-conjugated Antibody

 Ctrl IC006T
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Rat IgG2A PerCP‑conjugated Control Antibody

 Ctrl IC006C
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Have you used Rat IgG2A Isotype Control?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Order Details

Contact Us to Order
reload

Feedback

Customer Information
You May Also Like
 
Rat IgG2A PE-conjugated Antibody
 
Rat IgG2A Allophycocyanin Isotype Control
 
Rat IgG2A Alexa Fluor® 488‑conjugated Isotype Control
 
Rat IgG2A Fluorescein-conjugated Antibody
 
Rat IgG2A Alexa Fluor® 647-conjugated Antibody
 
Rat IgG2A Alexa Fluor® 700-conjugated Antibody
 
Rat IgG2A Isotype Control
 
Rat IgG2A Alexa Fluor® 405-conjugated Antibody
 
Rat IgG2A Biotinylated Isotype Control
 
Rat IgG2A Alexa Fluor® 594-conjugated Antibody
Related Products
Calculators

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Monoclonal
Antibody
Panels For
Screening

Learn More
Monoclonal Antibodies
R&D Systems Guarantee