Human/Rat SOX10 NorthernLights™ NL557-conjugated Antibody

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Product Details
Citations (2)

Human/Rat SOX10 NorthernLights™ NL557-conjugated Antibody Summary

Species Reactivity
Human, Rat
Detects human and rat SOX10. Epitope-mapping experiments indicated that clone 20B7 recognizes a determinant in the first 65 amino acids, which contains sequences unique to SOX10 (1).
Monoclonal Mouse IgG1 Clone # 20B7
Supplied in a saline solution containing BSA and Sodium Azide.
NL557 (Excitation= 557 nm, Emission= 574 nm)


Recommended Concentration
Please refer to the PDF datasheet for specifications.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: SOX10

SOX10 belongs to the SOX family of transcription factors which display diverse roles during development. In the central nervous system, SOX10 is required for the terminal differentiation of oligodendrocytes and myelination. In the peripheral nervous system, SOX10 maintains pluripotency of neural crest stem cells and suppresses neuronal differentiation.

  1. Lo, L. et al. (2002) Development 129:1553.
Long Name
Transcription Factor SOX10
Entrez Gene IDs
6663 (Human)
Alternate Names
DOM; MGC15649; PCWH; SOX10; SRY (sex determining region Y)-box 10; SRY-related HMG-box gene 10; transcription factor SOX-10; WS4; WS4C; WS4mouse, human homolog of

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Citations for Human/Rat SOX10 NorthernLights™ NL557-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. DNA methylation signatures of Alzheimer's disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types
    Authors: G Shireby, EL Dempster, S Policicchi, RG Smith, E Pishva, B Chioza, JP Davies, J Burrage, K Lunnon, D Seiler Vel, S Love, A Thomas, K Brookes, K Morgan, P Francis, E Hannon, J Mill
    Nature Communications, 2022-09-24;13(1):5620.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  2. Folate Metabolism Regulates Oligodendrocyte Survival and Differentiation by Modulating AMPK alpha Activity
    Authors: Qinjie Weng, Jiajia Wang, Jiaying Wang, Biqin Tan, Jing Wang, Haibo Wang et al.
    Scientific Reports


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