Human Resistin Alexa Fluor® 488-conjugated Antibody

Catalog #: AF1359G Datasheet / COA / SDS

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AF1359G-100UG

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Human Resistin Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Resistin in direct ELISAs and Western blots. In these formats, this antibody shows less than 2% cross-reactivity with rmResistin, rmRELM alpha and rmRELM beta.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human Resistin
Ser17-Pro108
Accession # Q9HD89

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Resistin

Human Resistin is an 11-12 kDa member of a small family of inflammation-related cysteine-rich polypeptides. It is named for its antagonistic activity towards insulin (resistance to insulin) and contains five intrachain disulfide bonds that generate a mixture of alpha -helices and beta -sheets. Secreted resistin forms disulfide-linked homodimers that likely oligomerize. Resistin may also form nondisulfide-linked heterodimers with RELM beta. One alternate splice form exists that shows an in-frame 26 amino acid (aa) deletion between amino acids 40 - 65. The significance is unclear. Mature human Resistin is 50% aa identical to human RELM beta and 56% aa identical to mouse Resistin.

Entrez Gene IDs

56729 (Human); 57264 (Mouse)

Alternate Names

Adipose tissue-specific secretory factor; ADSF; ADSFMGC126609; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich proteinprecursor 1; C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; Cysteine-rich secreted protein A12-alpha-like 2; Cysteine-rich secreted protein FIZZ3; FIZZ3; FIZZ3MGC126603; found in inflammatory zone 3; HXCP1; Resistin; RETN; RETN1; RSTNXCP1