Human SCP3/SYCP3 Antibody

Catalog # Availability Size / Price Qty
AF3750
AF3750-SP
Product Details
Citations (13)
FAQs
Supplemental Products
Reviews

Human SCP3/SYCP3 Antibody Summary

Species Reactivity
Human
Specificity
Detects human SCP3/SYCP3 in direct ELISAs and Western blots.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant human SCP3/SYCP3
Met1-Phe236
Accession # Q8IZU3
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Human SCP3/SYCP3

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Loading...
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: SCP3/SYCP3

SCP3 is a component of the synaptonemal complex, which is a meiosis-specific proteinaceous structure required for the pairing and segregation of homologous chromosomes. Human SCP3 is a 236 amino acid protein with a centrally located nuclear localization signal (NLS) and two C-terminal coiled coil domains. Human and mouse SCP3 share 71% amino acid sequence homology.

Long Name
Synaptonemal Complex Protein 3
Entrez Gene IDs
50511 (Human); 20962 (Mouse); 25561 (Rat)
Alternate Names
COR1; MGC71888; SCP3 chromosome 3 open reading frame 8; SCP3 COR1; SCP3; SCP-3; SYCP3; synaptonemal complex protein 3

Product Datasheets

You must select a language.

x

Citations for Human SCP3/SYCP3 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

13 Citations: Showing 1 - 10
Filter your results:

Filter by:

  1. Novel Hemizygous Mutations of TEX11 Cause Meiotic Arrest and Non-obstructive Azoospermia in Chinese Han Population
    Authors: Zhiyong Ji, Chencheng Yao, Chao Yang, Chuan Huang, Liangyu Zhao, Xia Han et al.
    Frontiers in Genetics
  2. Distinct prophase arrest mechanisms in human male meiosis
    Authors: Sabrina Z. Jan, Aldo Jongejan, Cindy M. Korver, Saskia K. M. van Daalen, Ans M. M. van Pelt, Sjoerd Repping et al.
    Development
  3. ATF7IP2, a meiosis-specific partner of SETDB1, is required for proper chromosome remodeling and crossover formation during spermatogenesis
    Authors: Shao, Q;Zhang, Y;Liu, Y;Shang, Y;Li, S;Liu, L;Wang, G;Zhou, X;Wang, P;Gao, J;Zhou, J;Zhang, L;Wang, S;
    Cell reports
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  4. Retinoic acid-induced differentiation of porcine prospermatogonia in�vitro
    Authors: X You, T Li, Y Cui, W Liu, Z Cheng, W Zeng, P Wang, Y Zheng
    Theriogenology, 2023-01-07;198(0):344-355.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: ICC
  5. Active DNA damage response signaling initiates and maintains meiotic sex chromosome inactivation
    Authors: H Abe, YH Yeh, Y Munakata, KI Ishiguro, PR Andreassen, SH Namekawa
    Nature Communications, 2022-11-28;13(1):7212.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  6. Novel copy number variations within SYCE1 caused meiotic arrest and non-obstructive azoospermia
    Authors: Y Huang, R Tian, J Xu, Z Ji, Y Zhang, L Zhao, C Yang, P Li, E Zhi, H Bai, S Han, J Luo, J Zhao, J Zhang, Z Zhou, Z Li, C Yao
    BMC medical genomics, 2022-06-19;15(1):137.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  7. SETDB1 Regulates Porcine Spermatogonial Adhesion and Proliferation through Modulating MMP3/10 Transcription
    Authors: R Liu, Z Liu, M Guo, W Zeng, Y Zheng
    Cells, 2022-01-22;11(3):.
    Species: Porcine
    Sample Types: Whole Tissue
    Applications: IHC
  8. Super-resolution imaging of RAD51 and DMC1 in DNA repair foci reveals dynamic distribution patterns in meiotic prophase
    Authors: JA Slotman, MW Paul, F Carofiglio, HM de Gruiter, T Vergroesen, L Koornneef, WA van Cappel, AB Houtsmulle, WM Baarends
    PLoS Genet., 2020-06-05;16(6):e1008595.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  9. HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis
    Authors: I Brandsma, K Sato, SE van Rossum, N van Vliet, E Sleddens, M Reuter, H Odijk, N van den Te, DHW Dekkers, K Bezstarost, JAA Demmers, A Maas, J Lebbink, C Wyman, J Essers, DC van Gent, WM Baarends, P Knipscheer, R Kanaar, AN Zelensky
    Cell Rep, 2019-06-25;27(13):3790-3798.e7.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  10. Repair of exogenous DNA double-strand breaks promotes chromosome synapsis in SPO11-mutant mouse meiocytes, and is altered in the absence of HORMAD1
    Authors: F Carofiglio, E Sleddens-L, E Wassenaar, A Inagaki, WA van Cappel, JA Grootegoed, A Toth, WM Baarends
    DNA Repair (Amst.), 2018-01-31;63(0):25-38.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  11. Metastable primordial germ cell-like state induced from mouse embryonic stem cells by Akt activation.
    Authors: Yamano N, Kimura T, Watanabe-Kushima S, Shinohara T, Nakano T
    Biochem. Biophys. Res. Commun., 2010-01-06;392(3):311-6.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  12. Novel bi-allelic MSH4 variants causes meiotic arrest and non-obstructive azoospermia
    Authors: Peng Li, Zhiyong Ji, Erlei Zhi, Yuxiang Zhang, Sha Han, Liangyu Zhao et al.
    Reproductive Biology and Endocrinology
  13. Bi-allelic SHOC1 loss-of-function mutations cause meiotic arrest and non-obstructive azoospermia
    Authors: Chencheng Yao, Chao Yang, Liangyu Zhao, Peng Li, Ruhui Tian, Huixing Chen et al.
    Journal of Medical Genetics

FAQs

No product specific FAQs exist for this product, however you may

View all Antibody FAQs
Loading...

Reviews for Human SCP3/SYCP3 Antibody

There are currently no reviews for this product. Be the first to review Human SCP3/SYCP3 Antibody and earn rewards!

Have you used Human SCP3/SYCP3 Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review