Human SCP3/SYCP3 Antibody
Human SCP3/SYCP3 Antibody Summary
Met1-Phe236
Accession # Q8IZU3
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Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: SCP3/SYCP3
SCP3 is a component of the synaptonemal complex, which is a meiosis-specific proteinaceous structure required for the pairing and segregation of homologous chromosomes. Human SCP3 is a 236 amino acid protein with a centrally located nuclear localization signal (NLS) and two C-terminal coiled coil domains. Human and mouse SCP3 share 71% amino acid sequence homology.
Product Datasheets
Citations for Human SCP3/SYCP3 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 7
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SETDB1 Regulates Porcine Spermatogonial Adhesion and Proliferation through Modulating MMP3/10 Transcription
Authors: R Liu, Z Liu, M Guo, W Zeng, Y Zheng
Cells, 2022;11(3):.
Species: Porcine
Sample Types: Whole Tissue
Applications: IHC -
Novel copy number variations within SYCE1 caused meiotic arrest and non-obstructive azoospermia
Authors: Y Huang, R Tian, J Xu, Z Ji, Y Zhang, L Zhao, C Yang, P Li, E Zhi, H Bai, S Han, J Luo, J Zhao, J Zhang, Z Zhou, Z Li, C Yao
BMC medical genomics, 2022;15(1):137.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Active DNA damage response signaling initiates and maintains meiotic sex chromosome inactivation
Authors: H Abe, YH Yeh, Y Munakata, KI Ishiguro, PR Andreassen, SH Namekawa
Nature Communications, 2022;13(1):7212.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Super-resolution imaging of RAD51 and DMC1 in DNA repair foci reveals dynamic distribution patterns in meiotic prophase
Authors: JA Slotman, MW Paul, F Carofiglio, HM de Gruiter, T Vergroesen, L Koornneef, WA van Cappel, AB Houtsmulle, WM Baarends
PLoS Genet., 2020;16(6):e1008595.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis
Authors: I Brandsma, K Sato, SE van Rossum, N van Vliet, E Sleddens, M Reuter, H Odijk, N van den Te, DHW Dekkers, K Bezstarost, JAA Demmers, A Maas, J Lebbink, C Wyman, J Essers, DC van Gent, WM Baarends, P Knipscheer, R Kanaar, AN Zelensky
Cell Rep, 2019;27(13):3790-3798.e7.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Repair of exogenous DNA double-strand breaks promotes chromosome synapsis in SPO11-mutant mouse meiocytes, and is altered in the absence of HORMAD1
Authors: F Carofiglio, E Sleddens-L, E Wassenaar, A Inagaki, WA van Cappel, JA Grootegoed, A Toth, WM Baarends
DNA Repair (Amst.), 2018;63(0):25-38.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Metastable primordial germ cell-like state induced from mouse embryonic stem cells by Akt activation.
Authors: Yamano N, Kimura T, Watanabe-Kushima S, Shinohara T, Nakano T
Biochem. Biophys. Res. Commun., 2010;392(3):311-6.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC
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