Human SCP3/SYCP3 Antibody

Catalog # Availability Size / Price Qty
AF3750
AF3750-SP
Product Details
Citations (2)
FAQs
Supplemental Products
Reviews

Human SCP3/SYCP3 Antibody Summary

Species Reactivity
Human
Specificity
Detects human SCP3/SYCP3 in direct ELISAs and Western blots.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant human SCP3/SYCP3
Met1-Phe236
Accession # Q8IZU3
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Human SCP3/SYCP3

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: SCP3/SYCP3

SCP3 is a component of the synaptonemal complex, which is a meiosis-specific proteinaceous structure required for the pairing and segregation of homologous chromosomes. Human SCP3 is a 236 amino acid protein with a centrally located nuclear localization signal (NLS) and two C-terminal coiled coil domains. Human and mouse SCP3 share 71% amino acid sequence homology.

Long Name
Synaptonemal Complex Protein 3
Entrez Gene IDs
50511 (Human); 20962 (Mouse); 25561 (Rat)
Alternate Names
COR1; MGC71888; SCP3 chromosome 3 open reading frame 8; SCP3 COR1; SCP3; SCP-3; SYCP3; synaptonemal complex protein 3

Product Datasheets

Citations for Human SCP3/SYCP3 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. Repair of exogenous DNA double-strand breaks promotes chromosome synapsis in SPO11-mutant mouse meiocytes, and is altered in the absence of HORMAD1
    Authors: F Carofiglio, E Sleddens-L, E Wassenaar, A Inagaki, WA van Cappel, JA Grootegoed, A Toth, WM Baarends
    DNA Repair (Amst.), 2018;63(0):25-38.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  2. Metastable primordial germ cell-like state induced from mouse embryonic stem cells by Akt activation.
    Authors: Yamano N, Kimura T, Watanabe-Kushima S, Shinohara T, Nakano T
    Biochem. Biophys. Res. Commun., 2010;392(3):311-6.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC

FAQs

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Isotype Controls

Reconstitution Buffers

Secondary Antibodies

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