Human SLAM/CD150 (NP_003028) VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC1516
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Human SLAM/CD150 (NP_003028) VersaClone cDNA Summary

Key Benefits

The Signaling Lymphocytic Activation Molecule (SLAM) family of receptor molecules is a subset of the CD2 family of receptors. SLAM proteins function as co-receptors for lymphocyte activation and/or adhesion and mediate tyrosine phosphorylation signals. SLAM receptor expression is mainly restricted to immune cells. SLAM, also known as CD150, is a transmembrane glycoprotein that is upregulated on activated B cells and T cells but downregulated on Th2 polarized cells. SLAM ligation promotes the activation of Th0/Th1 cells, B cells, eosinophils, mast cell, and macrophages. SLAM also functions as a cellular entry receptor for measles virus.

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

Product Datasheets

Background: SLAM/CD150

The Signaling Lymphocytic Activation Molecule (SLAM) family of receptor molecules is a subset of the CD2 family of receptors. SLAM proteins function as co-receptors for lymphocyte activation and/or adhesion and mediate tyrosine phosphorylation signals. SLAM receptor expression is mainly restricted to immune cells. SLAM, also known as CD150, is a transmembrane glycoprotein that is upregulated on activated B cells and T cells but downregulated on Th2 polarized cells. SLAM ligation promotes the activation of Th0/Th1 cells, B cells, eosinophils, mast cell, and macrophages. SLAM also functions as a cellular entry receptor for measles virus.

Long Name
Signaling Lymphocytic Activation Molecule
Entrez Gene IDs
6504 (Human); 27218 (Mouse)
Alternate Names
CD 150; CD150; CD150IPO-3; CDw150; IPO-3; signaling lymphocytic activation molecule family member 1; signaling lymphocytic activation molecule; SLAM; SLAMCD150 antigen; SLAMF1

Reagents Provided

Other Reagents Provided

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