Human Stanniocalcin 1/STC-1 Biotinylated Antibody
Human Stanniocalcin 1/STC-1 Biotinylated Antibody Summary
Accession # P52823
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Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Stanniocalcin 1/STC-1
Human STC-1 is a secreted disulfide-linked homodimeric phosphorylated glycoprotein hormone (50 kDa and higher molecular weight variants) that is related to the STC protein first discovered from corpuscles of stannius in fish. It is expressed in a wide variety of tissues and has endocrine/paracrine/autocrine functions relating to calcium and phosphate homeostasis, reproduction and development. The 230 amino acid (aa) mature STC-1 contains five intrachain disulfide and one interchain disulfide bond. Human STC-1 and STC-2 share approximately 30% aa sequence homology. STC-1 is highly homologous across species. Human STC-1 shares > 95% sequence homology with mouse, rat, and bovine STC-1.
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