Human TCL1B Alexa Fluor® 488-conjugated Antibody

Catalog #: AF6794G Datasheet / COA / SDS

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AF6794G-100UG

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Human TCL1B Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human TCL1B in direct ELISAs. In direct ELISAs, less than 5% cross-reactivity with recombinant human TCL1A is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human TCL1B
Ala2-Asp128 (Glu93Arg)
Accession # O95988

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: TCL1B

TCL1B (T cell leukemia protein 1B; also SYN1 and [p15]TML1) is a monomeric,15 kDa (predicted) member of the TCL1 family of proteins. It is expressed in the embryo and syncytiotrophoblast, and interacts with Akt1 and Akt2 kinase, promoting their activation and the subsequent deactivation of proapoptotic molecules. Human TCL1B is 128 amino acids (aa) in length. There is no definitive structural motif that characterizes TCL1B, save for a unique beta -barrel configuration. Full length human TCL1B shares less than 35% aa identity with five orthologous mouse TCL1B isoforms.

Long Name

T Cell Leukemia Protein 1B

Entrez Gene IDs

9623 (Human)

Alternate Names

MTCP1-like protein 1; Oncogene TCL1B; Oncogene TCL-1B; SYN-1; Syncytiotrophoblast-specific protein; T-cell leukemia/lymphoma 1B; T-cell leukemia/lymphoma protein 1B; T-cell lymphoma/leukemia 1B; TCL1; TCL1/MTCP1-like protein 1; TCL1B; TML1; TML1TCL1/ MTCP1-like 1