Human TEM7/PLXDC1 Isoform 1 Biotinylated Antibody

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Product Details
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Human TEM7/PLXDC1 Isoform 1 Biotinylated Antibody Summary

Species Reactivity
Detects human TEM7/PLXDC1 Isoform 1 in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human TEM8 is observed.
Polyclonal Sheep IgG
Antigen Affinity-purified
Mouse myeloma cell line NS0-derived recombinant human TEM7/PLXDC1 Isoform 1
Accession # ACE86780
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.


Recommended Concentration
Western Blot
0.1 µg/mL
Recombinant Human TEM7/PLXDC1 Isoform 1

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
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Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: TEM7/PLXDC1

TEM7 (Tumor endothelial marker 7; also TEM3 and Plexin domain-containing protein-1/PXDC1) is an 85 kDa member of the plexin family of proteins. It is one of a number of TEM designated molecules that are related only a name and not structural similarity. TEM7 is found on tumor endothelial cells, newly formed endothelial cells and neurons. It is known to bind nidogen. Mature human TEM7 is a type I transmembrane glycoprotein 482 amino acids (aa) in length. It contains an extracellular region (aa 19‑426) with one plexin domain (aa 303‑347). There are three isoform variants. One is intracellular and shows an alternate start site at Met74 accompanied by a 28 aa substitution for aa 331‑500. The other two are soluble, with one showing only the above 28 aa substitution and a second showing an eight aa substitution for aa 331‑500. Over aa 19‑426, human TEM7 shares 81% aa identity with mouse TEM7.

Long Name
Tumor Endothelial Marker 7/Plexin Domain Containing Protein 1
Entrez Gene IDs
57125 (Human); 72324 (Mouse); 303505 (Rat)
Alternate Names
FLJ45632; plexin domain containing 1,2410003I07Rik; plexin domain-containing protein 1; PLXDC1; TEM3; TEM3FLJ36270; TEM7; TEM7DKFZp686F0937; Tumor endothelial marker 3; Tumor endothelial marker 7

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