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Human TIM-1/KIM-1/HAVCR DuoSet ELISA

Catalog #: DY1750E
15 Citations Datasheet / COA / SDS

Discontinued Product

DY1750E has been discontinued.
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Citations (15)
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Human TIM-1/KIM-1/HAVCR DuoSet ELISA Summary

Specificity
Please see the product datasheet

* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.

Scientific Data

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Human TIM-1 / KIM-1 / HAVCR ELISA Standard Curve

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Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: TIM-1/KIM-1/HAVCR

TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.

Long Name:
T Cell Immunoglobulin Mucin-1
Entrez Gene IDs:
26762 (Human); 171283 (Mouse); 286934 (Rat); 102141332 (Cynomolgus Monkey)
Alternate Names:
CD365; HAVCR1; HAVCR-1; HAVCRT cell immunoglobin domain and mucin domain protein 1; hepatitis A virus cellular receptor 1; Kidney injury molecule 1; KIM1; KIM-1; T-cell immunoglobulin and mucin domain-containing protein 1; TIM1; TIM-1; TIM-1TIM; TIM1TIMD-1; TIMD1T-cell membrane protein 1

Citations for Human TIM-1/KIM-1/HAVCR DuoSet ELISA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

15 Citations: Showing 1 - 10
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  1. Combining renal cell arrest and damage biomarkers to predict progressive AKI in patient with sepsis
    Authors: X Tao, C Chen, W Luo, J Zhou, J Tian, X Yang, FF Hou
    Bmc Nephrology, 2021-12-15;22(1):415.
    Species: Human
    Sample Types: Urine
  2. Serum and urinary biomarkers for early detection of acute kidney injury following Hypnale spp. envenoming
    Authors: ES Wijewickra, F Mohamed, IB Gawaramman, ZH Endre, NA Buckley, GK Isbister
    PloS Neglected Tropical Diseases, 2021-12-06;15(12):e0010011.
    Species: Human
    Sample Types: Urine
  3. Urinary cytokines correlate with acute kidney injury in critically ill COVID-19 patients
    Authors: A Gradin, H Andersson, T Luther, SB Anderberg, S Rubertsson, M Lipcsey, M Åberg, A Larsson, R Frithiof, M Hultström
    Cytokine, 2021-05-24;146(0):155589.
    Species: Human
    Sample Types: Urine
  4. Successful Urine Multiplex Bead Assay to Measure Lupus Nephritis Activity
    Authors: EM Cody, MR Bennett, G Gulati, Q Ma, M Altaye, P Devarajan, HI Brunner
    Kidney international reports, 2021-04-28;6(7):1949-1960.
    Species: Human
    Sample Types: Urine
  5. Antisense oligonucleotide development for the selective modulation of CYP3A5 in renal disease
    Authors: KA Lidberg, AJ Annalora, M Jozic, DJ Elson, L Wang, TK Bammler, S Ramm, MB Monteiro, J Himmelfarb, CB Marcus, PL Iversen, EJ Kelly
    Scientific Reports, 2021-02-25;11(1):4722.
    Species: Human
    Sample Types: Cell Culture Supernates
  6. Early identification of acute kidney injury in Russell's viper (Daboia russelii) envenoming using renal biomarkers
    Authors: I Ratnayake, F Mohamed, NA Buckley, IB Gawaramman, DM Dissanayak, U Chathurang, M Munasinghe, K Maduwage, S Jayamanne, ZH Endre, GK Isbister
    PLoS Negl Trop Dis, 2019-07-01;13(7):e0007486.
    Species: Human
    Sample Types: Urine
  7. Acute Kidney Injury Biomarkers Predict an Increase in Serum Milrinone Concentration Earlier Than Serum Creatinine-Defined Acute Kidney Injury in Infants After Cardiac Surgery
    Authors: KM Gist, DS Cooper, J Wrona, S Faubel, C Altmann, Z Gao, BS Marino, J Alten, KM Hock, T Mizuno, AA Vinks, MS Joy, MF Wempe, MR Bennett, SL Goldstein
    Ther Drug Monit, 2018-04-01;40(2):186-194.
    Species: Human
    Sample Types: Urine
  8. Propofol-based anaesthesia versus sevoflurane-based anaesthesia for living donor kidney transplantation: results of the VAPOR-1 randomized controlled trial
    Authors: GJ Nieuwenhui, VB Nieuwenhui, MAJ Seelen, SP Berger, MC van den He, JGM Burgerhof, PJ Ottens, RJ Ploeg, HGD Leuvenink, MMRF Struys
    Br J Anaesth, 2017-05-01;118(5):720-732.
    Species: Human
    Sample Types: Urine
  9. Dexamethasone Modifies Cystatin C-Based Diagnosis of Acute Kidney Injury During Cisplatin-Based Chemotherapy
    Authors: TJ Pianta, JW Pickering, L Succar, M Chin, T Davidson, NA Buckley, F Mohamed, ZH Endre
    Kidney Blood Press. Res, 2017-03-17;42(1):62-75.
    Species: Human
    Sample Types: Urine
  10. Expression of Tim-1 in primary CNS lymphoma
    Cancer Med, 2016-10-05;5(11):3235-3245.
    Species: Human
    Sample Types: CSF
  11. Urinary adiponectin is an independent predictor of progression to end-stage renal disease in patients with type 1 diabetes and diabetic nephropathy.
    Authors: Panduru N, Saraheimo M, Forsblom C, Thorn L, Gordin D, Waden J, Tolonen N, Bierhaus A, Humpert P, Groop P
    Diabetes Care, 2015-02-26;38(5):883-90.
    Species: Human
    Sample Types: Urine
  12. Assessment of Worldwide Acute Kidney Injury, Renal Angina and Epidemiology in critically ill children (AWARE): study protocol for a prospective observational study.
    Authors: Basu R, Kaddourah A, Terrell T, Mottes T, Arnold P, Jacobs J, Andringa J, Goldstein S
    BMC Nephrol, 2015-02-26;16(0):24.
    Species: Human
    Sample Types: Urine
  13. Soluble TNF receptors and kidney dysfunction in the elderly.
    Authors: Carlsson A, Larsson T, Helmersson-Karlqvist J, Larsson A, Lind L, Arnlov J
    J Am Soc Nephrol, 2014-02-07;25(6):1313-20.
    Species: Human
    Sample Types: Urine
  14. Urinary L-FABP and anaemia: distinct roles of urinary markers in type 2 diabetes.
    Authors: von Eynatten M, Baumann M, Heemann U
    Eur. J. Clin. Invest., 2009-11-11;40(2):95-102.
    Species: Human
    Sample Types: Urine
  15. Assay validation for KIM-1: human urinary renal dysfunction biomarker.
    Authors: Chaturvedi S, Farmer T, Kapke GF
    Int. J. Biol. Sci., 2009-01-19;5(2):128-34.
    Species: Human
    Sample Types: Urine

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