Human TRAIL/TNFSF10 PE-conjugated Antibody
Human TRAIL/TNFSF10 PE-conjugated Antibody Summary
Thr95-Gly281
Accession # P50591
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Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of TRAIL/TNFSF10 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs), untreated (A) or treated (B) with rhIFN- a for 48 hours (150 ng/mL), were stained with Mouse Anti-Human TRAIL/TNFSF10 PE-conjugated Monoclonal Antibody (Catalog # FAB687P) and Mouse Anti-Human CD14 APC-conjugated Monoclonal Antibody (Catalog # 3832A). Quadrant markers were set based on control antibody staining (Catalog # IC002P).
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Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: TRAIL/TNFSF10
TRAIL is a type II transmembrane protein belonging to the TNF superfamily and is now designated TNFSF10. TRAIL is active as a homotrimer and is produced by a variety of cell types in both the membrane bound form and also as a soluble molecule. It binds to any of the four TRAIL receptors as well as to Osteoprotegerin.
Product Datasheets
Citations for Human TRAIL/TNFSF10 PE-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 5
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Defective Regulation of Membrane TNF&alpha Expression in Dendritic Cells of Glioblastoma Patients Leads to the Impairment of Cytotoxic Activity against Autologous Tumor Cells
Authors: T Tyrinova, O Leplina, S Mishinov, M Tikhonova, E Dolgova, A Proskurina, V Stupack, S Bogachev, A Ostanin, E Chernykh
Int J Mol Sci, 2020;21(8):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Activated hepatic stellate cells impair NK cell anti-fibrosis capacity through a TGF-?-dependent emperipolesis in HBV cirrhotic patients
Authors: J Shi, J Zhao, X Zhang, Y Cheng, J Hu, Y Li, X Zhao, Q Shang, Y Sun, B Tu, L Shi, B Gao, FS Wang, Z Zhang
Sci Rep, 2017;7(0):44544.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Peg-Interferon Lambda Treatment Induces Robust Innate and Adaptive Immunity in Chronic Hepatitis B Patients
Authors: S Phillips, S Mistry, A Riva, H Cooksley, T Hadzhiolov, S Plavova, K Katzarov, M Simonova, S Zeuzem, C Woffendin, PJ Chen, CY Peng, TT Chang, S Lueth, R De Knegt, MS Choi, H Wedemeyer, M Dao, CW Kim, HC Chu, M Wind-Rotol, R Williams, E Cooney, S Chokshi
Front Immunol, 2017;8(0):621.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Extracellular HCV-core protein induces an immature regulatory phenotype in NK cells: implications for outcome of acute infection.
Authors: Golden-Mason L, Hahn Y, Strong M, Cheng L, Rosen H
PLoS ONE, 2014;9(7):e103219.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
TRAIL(+) human plasmacytoid dendritic cells kill tumor cells in vitro: mechanisms of imiquimod- and IFN-alpha-mediated antitumor reactivity.
Authors: Kalb ML, Glaser A, Stary G, Koszik F, Stingl G
J. Immunol., 2012;188(4):1583-91.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
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