Human Tyrosylprotein Sulfotransferase 2/TPST2 Alexa Fluor® 647-conjugated Antibody

Catalog #: AF6236R Datasheet / COA / SDS

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AF6236R-100UG

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All Tyrosylprotein Sulfotransferase 2/TPST2 Antibodies

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Human Tyrosylprotein Sulfotransferase 2/TPST2 Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Tyrosylprotein Sulfotransferase 2/TPST2 in direct ELISAs and Western blots. In direct ELISAs, less than 7% cross-reactivity with recombinant human TPST1 is observed.

Source

Polyclonal Sheep IgG

Purification

Antigen Affinity-purified

Immunogen

Chinese hamster ovary cell line CHO-derived recominant human Tyrosylprotein Sulfotransferase 2/TPST2
Gln26-Ser377 (predicted)
Accession # O60704

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Tyrosylprotein Sulfotransferase 2/TPST2

Human Tyrosylprotein Sulfotransferase 2 (TPST2) is a 42 kDa (predicted) member of a sulfotransferase family. Two human tyrosylprotein sulfotransferases (TPSTs), TPST1 and TPST2 mediate tyrosine O-sulfation of more than 60 different proteins in the Golgi, transferring sulfate from 3'-phosphoadenosine 5'‑phosphosulfate to tyrosine residues contained in polypeptides with acidic motifs to form a tyrosine O-sulfate ester. TSPT1 and TSPT2 are widely expressed, they show similar tissue distribution and overlapping substrate specificity.

Entrez Gene IDs

8459 (Human)

Alternate Names

EC 2.8.2.20; TPST2; TPST-2; tyrosylprotein phosphotransferase 2; Tyrosylprotein Sulfotransferase 2; tyrosylprotein sulfotransferase 2protein-tyrosine sulfotransferase 2; tyrosylprotein sulfotransferase-2