Human VIPR2 Alexa Fluor® 647-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: VIPR2

Human VIP R2 (Vasoactive intestinal polypeptide receptor 2) is a 47 kDa (predicted) seven transmembrane receptor that belongs to the G protein coupled receptor 2 family of proteins. In addition to the seven transmembrane regions, the mature chain also contains in its first extracellular region a hormone receptor domain (aa 49‑114), which includes three N-linked glycosylation sites. Human VIP R2 shares 85% aa identity with mouse and rat VIP R2. VIP R2 is expressed predominantly in skeletal muscle and to a lesser extent in the brain, heart, pancreas, and placenta. VIP R2 is coupled to a cAMP mediated signal transduction pathway and binds VIP and pituitary adenylate cyclase activating polypeptide (PACAP).

Product Datasheets

Related Research Areas

• G Protein-Coupled Receptors in Obesity and Related Metabolic Disorders
• Microglia Homeostasis
• Neurotransmitter Receptors
• Neurotransmitter Receptors, Transporters, and Ion Channels
• Obesity
• Vasoactive Peptide Hormones and Regulators