Wnt-5a is a palmitoylated and secreted glycoprotein that is a key molecule in embryonic development and post-natal tissue homeostasis. Wnt‑5a signals through a variety of receptors and cofactors including Frizzled-2, -3, -4, -5, -7, and -8, ROR2, Ryk, MCAM/CD146, LRP-6, sFRP-1, and Vang-like Protein 2. It is expressed by brainstem astrocytes, mammary epithelial cells, CD34+ primitive progenitor stem cells, chondrocytes, vascular pericytes and smooth muscle cells, and mesenchymal cells. Aberrant Wnt-5a expression and function is associated with the development of cancer, fibrosis, and chronic inflammation.
Human Wnt-5a (NP_003383.4) VersaClone cDNA
R&D Systems | Catalog # RDC3681
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Wnt-5a
Long Name
Wingless-type MMTV Integration Site Family, Member 5a
Alternate Names
Wnt5a
Gene Symbol
WNT5A
UniProt
Additional Wnt-5a Products
Product Documents for Human Wnt-5a (NP_003383.4) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human Wnt-5a (NP_003383.4) VersaClone cDNA
For research use only
Related Research Areas
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