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ICI 185,282

Catalog #: 0836
1 Citation Datasheet / COA / SDS

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ICI 185,282 | CAS No. 106393-80-0 | Prostanoid Receptor Antagonists
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Description: Potent thromboxane receptor antagonist

Chemical Name: 5-(Z)-7-(4-o-Hydroxyphenyl-2-trifluoromethyl-1,3 dioxan-cis-5-yl)heptenoic acid

Product Details
Citations (1)
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Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

Potent thromboxane receptor antagonist.

Technical Data

M.Wt:
374.36
Formula:
C18H21F3O5
Solubility:
Soluble in DMSO
Storage:
Desiccate at -20°C
CAS No:
106393-80-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold with the permission of AstraZeneca UK Ltd.

Background References

  1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
    Fox JT, Sakamuru S, Huang R
    Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
  2. Studies in the guinea-pig with ICI 185,282: a thromboxane A2 receptor antagonist.
    Birch et al.
    J.Pharm.Pharmacol., 1988;40:706

Product Datasheets

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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Citation for ICI 185,282

The citations listed below are publications that use Tocris products. Selected citations for ICI 185,282 include:

1 Citation: Showing 1 - 1

  1. Vasoconstrictor potential of coronary aspirate from patients undergoing stenting of saphenous vein aortocoronary bypass grafts and its pharmacological attenuation.
    Authors: Kleinbongard Et al.
    Circ Res  2011;108:344

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