Ifenprodil hemitartrate

Tocris Bioscience | Catalog # 0545

Non-competitive NMDA antagonist; also σ ligand
Tocris Bioscience

Key Product Details

Description

Non-competitive NMDA antagonist; also σ ligand
View all NMDA Receptor Antagonists »

Product Description

Ifenprodil hemitartrate is a NMDA receptor antagonist, acting at the polyamine site. Also an α-adrenergic vasodilator. σ2 ligand displaying about 3-fold selectivity over σ1 sites.

Product Specifications for Ifenprodil hemitartrate

Molecular Weight

400.49

Formula

C21H27NO2.½C4H6O6

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(1R*,2S*)-erythro-2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol hemi-(DL)-tartrate

PubChem ID

3689

InChI Key

UYNVMODNBIQBMV-UHFFFAOYSA-N

SMILES

OC1=CC=C([C@H]([C@@H](N2CCC(CC3=CC=CC=C3)CC2)C)O)C=C1.OC4=CC=C([C@H]([C@@H](N5CCC(CC6=CC=CC=C6)CC5)C)O)C=C4.O=C([C@H]([C@@H](C(O)=O)O)O)O.OC7=CC=C([C@@H]([C@H](N8CCC(CC9=CC=CC=C9)CC8)C)O)C=C7.OC%10=CC=C([C@@H]([C@H](N%11CCC(CC%12=CC=CC=C%12)CC%11)C)O)C=C%10.O=C([C@@H]([C@H](C(O)=O)O)O)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 4 10
DMSO 40.05 100

Preparing Stock Solutions for Ifenprodil hemitartrate

The following data is based on the product molecular weight 400.49.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.50 mL 12.48 mL 24.97 mL
5 mM 0.50 mL 2.50 mL 4.99 mL
10 mM 0.25 mL 1.25 mL 2.50 mL
50 mM 0.05 mL 0.25 mL 0.50 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 60 publications citing the usage of this product.

Product Documents for Ifenprodil hemitartrate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Ifenprodil hemitartrate

For research use only

Citations for Ifenprodil hemitartrate

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