Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin, Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Format

BSA Free
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Product Specifications

Immunogen

IFIT3 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IFIT3. The immunogen is located within amino acids 380 - 430 of IFIT3.

Specificity

IFIT3 antibody is human specific. This antibody is predicted to not cross-react with other members of the IFIT protein family.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for IFIT3 Antibody - BSA Free

IFIT3 Antibody

Western Blot: IFIT3 Antibody [NBP3-27893] -

Western Blot: IFIT3 Antibody [NBP3-27893] - Western blot analysis of IFIT3 in HepG2 cell lysate with IFIT3 antibody at 1 u/ml.
IFIT3 Antibody

Immunohistochemistry: IFIT3 Antibody [NBP3-27893] -

Immunohistochemistry: IFIT3 Antibody [NBP3-27893] - Immunohistochemistry of IFIT3 in human liver tissue with IFIT3 antibody at 5 u/mL.

Applications for IFIT3 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

5 ug/mL

Western Blot

1 - 2 ug/mL

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IFIT3

IFIT3, also known as IFIT4, IFI60, and RIGG, has been identified as a key element in the IFN-alpha anti-viral pathway. Additionally, IFIT3 binding negatively regulates the apoptotic effects of ISG54. IFIT3 is also a key target of STAT1, which is important in regulating IFN responses. One study has shown that expression of RIGG in a human monocytoma line led to growth arrest at the G1/S transition.

Alternate Names

CIG-49, GARG-49, IFI60Retinoic acid-induced gene G protein, IFIT-3, IFIT-4, IFIT4IFI-60K, interferon-induced protein with tetratricopeptide repeats 3, Interferon-induced protein with tetratricopeptide repeats 4Interferon-induced 60 kDa protein, IRG2, ISG60, ISG-60, RIG-GCIG49

Gene Symbol

IFIT3

UniProt

Additional IFIT3 Products

Product Documents for IFIT3 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for IFIT3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

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