IFN-alpha/beta R2 Antibody

Novus Biologicals | Catalog # NBP1-20934

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Peptide ELISA, Flow Cytometry

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all IFN-alpha/beta R2 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence SYDSPDYTDESCT corresponding to internal region according to NP_000865.2, NP_997467.1, NP_997468.1.

Epitope

internal region

Specificity

This antibody is expected to recognise all three reported isoforms (NP_000865.2 ; NP_997467.1; NP_997468.1 )

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for IFN-alpha/beta R2 Antibody

Immunohistochemistry-Paraffin: IFN-alpha/beta R2 Antibody [NBP1-20934]

Immunohistochemistry-Paraffin: IFN-alpha/beta R2 Antibody [NBP1-20934]

Immunohistochemistry-Paraffin: IFN-alpha/beta R2 Antibody [NBP1-20934] - (5ug/ml) staining of Human Placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Flow Cytometry: IFN-alpha/beta R2 Antibody [NBP1-20934]

Flow Cytometry: IFN-alpha/beta R2 Antibody [NBP1-20934]

Flow Cytometry: IFN-alpha/beta R2 Antibody [NBP1-20934] - Flow cytometric analysis of paraformaldehyde fixed K562 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.
Immunohistochemistry-Paraffin: IFN-alpha/beta R2 Antibody [NBP1-20934]

Immunohistochemistry-Paraffin: IFN-alpha/beta R2 Antibody [NBP1-20934]

Immunohistochemistry-Paraffin: IFN-alpha/beta R2 Antibody [NBP1-20934] - (5ug/ml) staining of Human Prostate. Steamed antigen retrieval with citrate buffer Ph 6, AP-staining.

Applications for IFN-alpha/beta R2 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

5 ug/mL

Peptide ELISA

Detection limit 1:32000

Western Blot

0.2 ug/mL

Flow Cytometry Panel Builder

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Advanced Features

  • Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
  • Spillover Popups - Visualize the spectra of individual fluorochromes
  • Antigen Density Selector - Match fluorochrome brightness with antigen density
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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: IFN-alpha/beta R2

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene.

Long Name

Interferon alpha/beta Receptor 2

Alternate Names

IFN-aR2, IFN-bR2, IFNAR2, IFNbR2

Entrez Gene IDs

3455 (Human)

Gene Symbol

IFNAR2

UniProt

NP_000865.2 (Human)

Additional IFN-alpha/beta R2 Products

Product Documents for IFN-alpha/beta R2 Antibody

Certificate of Analysis

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Product Specific Notices for IFN-alpha/beta R2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for IFN-alpha/beta R2 Antibody

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Protocols

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FAQs

No product specific FAQs exist for this product.

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Associated Pathways

Jak/STAT Signaling Pathway Jak/STAT Signaling Pathway Thumbnail