Recombinant Canine IL-1ra/IL-1F3/IL1RN Protein

Name: Recombinant Canine IL-1ra/IL-1F3/IL1RN Protein
Brand: Novus Biologicals
SKU: NBP2-62452
Price: 329 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-62452

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Product Specifications
Scientific Data
Preparation & Storage
Calculators
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Source

Pichia pastoris

Applications

Western Blot, ELISA

View all IL-1ra/IL-1F3 Proteins and Enzymes »

Product Specifications

Description

Recombinant dog interleukin-1RA.

Source:Pichia pastoris

Amino Acid Sequence:152 amino acid sequence of native canine IL-1RA.

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

17.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Canine IL-1ra/IL-1F3/IL1RN Protein

ELISA: Recombinant Canine IL-1ra/IL-1F3/IL1RN Protein [NBP2-62452] -

ELISA: Recombinant Canine IL-1ra/IL-1F3/IL1RN Protein [NBP2-62452] - Dog Interleukin-1RA ELISA

Recombinant Dog interleukin-1RA detected using Goat anti Dog interleukin-1RA as the capture reagent and Goat anti Dog interleukin-1RA:Biotin as the detection reagent followed by Streptavidin:HRP

Formulation, Preparation, and Storage

NBP2-62452

Preparation Method	Recombinant protein expressed in Pichia pastoris and purified by ion-exchange chromatography.
Formulation	PBS
Preservative	10% Trehalose
Concentration	Lyoph
Reconstitution	Reconstitute with 20 ul sterile PBS containing 0.1% carrier protein. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix vial after reconstitution.
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20C. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background: IL-1ra/IL-1F3

IL-1ra (IL-1 receptor antagonist) is a widely expressed acute phase protein that serves to dampen inflammation. IL-1ra binds to both IL-1 RI and IL-1 RII. It competitively inhibits IL-1 (alpha or beta) binding to IL-1 RI and does not trigger recruitment of the accessory molecule IL-1 R AcP or activation of IL-1 RI signaling. IL-1ra blocks the proinflammatory actions of IL-1 including Prostaglandin E2 and IL-6 release from endothelial cells, fever generation, thrombocytosis, the production of hepatic acute phase proteins, and neutrophil expansion and infiltration.

Long Name

Interleukin 1 Receptor Antagonist

Alternate Names

DIRA, ICIL-1ra, IL-1F3, IL-1ra3, IL-1RN, IL1ra, IL1RN, MVCD4

Gene Symbol

IL1RN

Additional IL-1ra/IL-1F3 Products

Product Documents for Recombinant Canine IL-1ra/IL-1F3/IL1RN Protein

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Certificate of Analysis

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Product Specific Notices for Recombinant Canine IL-1ra/IL-1F3/IL1RN Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.