IL-21R Antibody

Name: IL-21R Antibody
Brand: Novus Biologicals
SKU: NBP1-87502
Price: 569 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-87502

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

View all IL-21R Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: FMPLYKGCSGDFKKWVGAPFTGSSLELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGGSAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IL-21R Antibody

Western Blot: IL-21R Antibody [NBP1-87502]

Western Blot: IL-21R Antibody [NBP1-87502] - Analysis in control (vector only transfected HEK293T lysate) and IL21R over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

Immunohistochemistry: IL-21R Antibody [NBP1-87502]

Immunohistochemistry: IL-21R Antibody [NBP1-87502] - FISH analysis of BM aspirates using the A20/BLIMP1/SHGC-79576 Three Color Probe (Cancer Genetics Italia(TM)) and IL21R staining of a BM biopsied specimen. Green, red, and yellow signals represent BLIMP1, A20, and SHGC-79576, respectively. (c) >70% positivity of IL-21R in lymphoplasmacytic cells and plasma cells (original magnification x600). (d) <30% positivity of IL-21R in lymphoplasmacytic cells and plasma cells (original magnification x600). Image collected and cropped by CiteAb from the following publication (https://www.hindawi.com/journals/bmri/2018/6728128/), licensed under a CC-BY license.

Applications for IL-21R Antibody

Application

Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500-1:1000

Western Blot

0.04-0.4 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-21R

IL21 Receptor is a novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling. Both IL-21R and the gc are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.

Long Name

Interleukin 21 Receptor

Alternate Names

CD360, IL-21 R, IL21R, NILR

Gene Symbol

IL21R

Additional IL-21R Products

Product Documents for IL-21R Antibody

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Certificate of Analysis

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Product Specific Notices for IL-21R Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.