Chemical Name:N-[4-(2,4-Dimethylphenyl)-2-thiazolyl]benzamide hydrochloride
Biological Activity Hec1 inhibitor. Binds Hec1, inhibiting its association with Nek2 and kinetochores. Causes arrest of mitosis and inhibits proliferation in breast cancer cell lines (GI50= 10 - 20 μM).
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Desiccate at +4°C
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