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INH1

Catalog #: 3551
1 Citation Datasheet / COA / SDS

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3551 has been discontinued.
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INH1 | CAS No. 1780260-01-6 | Mitosis-Related Compounds
1 Image
Description: Hec1 inhibitor; causes arrest of mitosis

Chemical Name: N-[4-(2,4-Dimethylphenyl)-2-thiazolyl]benzamide hydrochloride

Purity: ≥99%

Product Details
Citations (1)
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Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

INH1 is a hec1 inhibitor. Binds Hec1, inhibiting its association with Nek2 and kinetochores. Causes arrest of mitosis and inhibits proliferation in breast cancer cell lines (GI50= 10 - 20 μM).

Technical Data

M.Wt:
344.86
Formula:
C18H16N2OS.HCl
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:
≥99%
Storage:
Desiccate at +4°C
CAS No:
1780260-01-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citation for INH1

The citations listed below are publications that use Tocris products. Selected citations for INH1 include:

1 Citation: Showing 1 - 1

  1. An RNAi-based screen reveals PLK1, CDK1 and NDC80 as potential therapeutic targets in malignant pleural mesothelioma.
    Authors: Linton Et al.
    Br J Cancer  2014;110:510

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