Integrin alpha 3/CD49c Antibody (CL6937) - BSA Free

Novus Biologicals | Catalog # NBP2-76515

Novus Biologicals
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Key Product Details

Validated by

Knockout/Knockdown, Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Knockdown Validated

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL6937

Format

BSA Free
View all Integrin alpha 3/CD49c Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed using a recombinant protein derived from P26006, with the exact immunogen sequence remaining proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84)% and Rat (82)%

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Integrin alpha 3/CD49c Antibody (CL6937) - BSA Free

Western Blot: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Western Blot: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Western Blot: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515] - Analysis in U-87MG ATCC cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-ITGA3 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.
Immunohistochemistry-Paraffin: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Immunohistochemistry-Paraffin: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Immunohistochemistry-Paraffin: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515] - Staining of human liver shows no positivity in hepatocytes as expected.
Western Blot: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Western Blot: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Western Blot: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515] - Analysis in human cell line U-87 MG.
Immunohistochemistry-Paraffin: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Immunohistochemistry-Paraffin: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Immunohistochemistry-Paraffin: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515] - Analysis in human lung and liver tissues. Corresponding ITGA3 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Immunohistochemistry-Paraffin: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Immunohistochemistry-Paraffin: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515] - Staining of human lung shows strong membranous positivity in pneumocytes.
Immunohistochemistry-Paraffin: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Immunohistochemistry-Paraffin: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Immunohistochemistry-Paraffin: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515] - Staining of human colon shows strong membranous positivity in glandular cells.
Immunohistochemistry-Paraffin: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Immunohistochemistry-Paraffin: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Immunohistochemistry-Paraffin: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515] - Staining of human placenta shows strong membranous positivity in trophoblastic cells.

Applications for Integrin alpha 3/CD49c Antibody (CL6937) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:100 - 1:250

Immunohistochemistry-Paraffin

1:100 - 1:250

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha 3/CD49c

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 3 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that interacts with many extracellular-matrix proteins. The alpha 3 beta 1 integrin is known variously as: very late (activation) antigen 3 (VLA3), very common antigen 2 (VCA2), extracellular matrix receptor 1 (ECMR1), and galactoprotein b3 (GAPB3).

Alternate Names

CD49c, ITGA3

Gene Symbol

ITGA3

Additional Integrin alpha 3/CD49c Products

Product Documents for Integrin alpha 3/CD49c Antibody (CL6937) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Integrin alpha 3/CD49c Antibody (CL6937) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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