Integrin alpha 4 beta 7/LPAM-1 Antibody (111D9.03) [Alexa Fluor® 488]

Name: Integrin alpha 4 beta 7/LPAM-1 Antibody (111D9.03) [Alexa Fluor® 488]
Brand: Novus Biologicals
SKU: DDX1434A488
Price: 579 USD
Availability: InStock

Novus Biologicals | Catalog # DDX1434A488

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Product Specifications
Applications
Spectra Viewer
Flow Cytometry
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human, Porcine

Applications

Flow Cytometry, Flow (Cell Surface), Immunocytochemistry/ Immunofluorescence

Label

Alexa Fluor 488 (Excitation = 488 nm, Emission = 515-545 nm)

Antibody Source

Monoclonal Mouse IgA Clone # 111D9.03

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Product Specifications

Immunogen

rhua4b7 (R&D systems) and RPMI 8866 cells

Reactivity Notes

Use in Porcine reported in scientific literature (PMID:33809123).

Clonality

Monoclonal

Host

Mouse

Isotype

IgA

Applications for Integrin alpha 4 beta 7/LPAM-1 Antibody (111D9.03) [Alexa Fluor® 488]

Application

Recommended Usage

Flow (Cell Surface)

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer

Flow Cytometry Panel Builder

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Save time and reduce costly mistakes by quickly finding compatible reagents using the Panel Builder Tool.

Advanced Features

Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
Spillover Popups - Visualize the spectra of individual fluorochromes
Antigen Density Selector - Match fluorochrome brightness with antigen density

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Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Integrin alpha 4 beta 7/LPAM-1

The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as integrin alpha4beta7, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha4beta7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. (1-4) The monoclonal antibody DATK32 recognizes a conformational epitope on the heterodimer. (1,2)

Alternate Names

CD49d/beta7, LPAM-1, LPAM1

Gene Symbol

ITGA4

Additional Integrin alpha 4 beta 7/LPAM-1 Products

Product Documents for Integrin alpha 4 beta 7/LPAM-1 Antibody (111D9.03) [Alexa Fluor® 488]

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Certificate of Analysis

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Product Specific Notices for Integrin alpha 4 beta 7/LPAM-1 Antibody (111D9.03) [Alexa Fluor® 488]

This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.