Integrin alpha 4 beta 7/LPAM-1 Antibody (111D9.03) - Azide and BSA Free

Name: Integrin alpha 4 beta 7/LPAM-1 Antibody (111D9.03) - Azide and BSA Free
Brand: Novus Biologicals
SKU: DDX1434P-100
Price: 479 USD
Availability: InStock

Novus Biologicals | Catalog # DDX1434P-100

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Citations (4)

Product Documents

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Product Specifications
Scientific Data
Applications
Flow Cytometry
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Validated:

Human, Porcine

Cited:

Human, Porcine

Applications

Validated:

Flow Cytometry, Flow (Cell Surface), Immunocytochemistry/ Immunofluorescence, Chromatin Immunoprecipitation (ChIP), Binding Activity

Cited:

Immunohistochemistry-Frozen, Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgA Clone # 111D9.03

Format

Azide and BSA Free

View all Integrin alpha 4 beta 7/LPAM-1 Primary Antibodies »

Product Specifications

Immunogen

rhua4b7 (R&D systems) and RPMI 8866 cells

Reactivity Notes

Use in Porcine reported in scientific literature (PMID:33809123).

Clonality

Monoclonal

Host

Mouse

Isotype

IgA

Theoretical MW

130 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images

Immunocytochemistry/ Immunofluorescence: Integrin alpha 4 beta 7/LPAM-1 Antibody (111D9.03) [DDX1434P-100]

Immunocytochemistry/Immunofluorescence: Integrin alpha 4 beta 7/LPAM-1 Antibody (111D9.03) [DDX1434P-100] - Gut sections (Crohn's disease).

Flow Cytometry: Integrin alpha 4 beta 7/LPAM-1 Antibody (111D9.03) [DDX1434P-100]

Flow Cytometry: Integrin alpha 4 beta 7/LPAM-1 Antibody (111D9.03) [DDX1434P-100] - FACS staining of RPMI 8866 cells (alpha4+beta7+) and HEK transfected cells with DDX1434(111D9) monoclonal antibody.

Applications

Application

Recommended Usage

Flow Cytometry

1:10-1:1000

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Formulation, Preparation, and Storage

Purification

Ion exchange chromatography

Formulation

Tris-NaCl pH 8

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha 4 beta 7/LPAM-1

The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as integrin alpha4beta7, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha4beta7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. (1-4) The monoclonal antibody DATK32 recognizes a conformational epitope on the heterodimer. (1,2)

Alternate Names

CD49d/beta7, LPAM-1, LPAM1

Gene Symbol

ITGA4

Additional Integrin alpha 4 beta 7/LPAM-1 Products

Product Documents

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Certificate of Analysis

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Product Specific Notices

This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.