Integrin alpha V/CD51 Antibody (23C6)

Name: Integrin alpha V/CD51 Antibody (23C6)
Brand: Novus Biologicals
SKU: NBP3-07525
Price: 419 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-07525

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Product Documents

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human, Bovine (Negative), Chicken, Rabbit (Negative)

Applications

ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG₁ kappa Clone # 23C6

View all Integrin alpha V/CD51 Primary Antibodies »

Product Specifications

Immunogen

Osteoclasts from osteoclastomas

Reactivity Notes

Does not react with Bovine or Porcine or Rabbit.

Localization

Cell Surface

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-08850)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Applications for Integrin alpha V/CD51 Antibody (23C6)

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

ELISA: For coating, order antibody without BSA).
Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Integrin alpha V/CD51

Integrin alpha V chain interacts with the integrin beta 3 subunit/CD61 to form the alpha-V-beta-3 heterodimer/vitronectin receptor. It is expressed on endothelial cells, some activated leukocytes, NK cells, macrophages, neutrophils, and platelets. Integrin alpha V also forms heterodimers with the integrin beta 1, beta 5, beta 6, and beta 8 subunits. Alpha-V-beta-3 is an activation dependent receptor for platelet attachment and spreading on vitronectin and other matrix components.

Alternate Names

CD51, ITGAV, MSK8, Vitronectin Receptor alpha, VNRA

Gene Symbol

ITGAV

UniProt

P06756

Additional Integrin alpha V/CD51 Products

Product Documents for Integrin alpha V/CD51 Antibody (23C6)

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Certificate of Analysis

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Product Specific Notices for Integrin alpha V/CD51 Antibody (23C6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.