Integrin alpha V/CD51 Antibody (23C6) [DyLight 350]

Name: Integrin alpha V/CD51 Antibody (23C6) [DyLight 350]
Brand: Novus Biologicals
SKU: NBP3-08850UV
Price: 499 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-08850UV

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Product Documents

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human, Bovine (Negative), Chicken, Rabbit (Negative)

Applications

ELISA

Label

DyLight 350 (Excitation = 353 nm, Emission = 432 nm)

Antibody Source

Monoclonal Mouse IgG₁ kappa Clone # 23C6

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Product Specifications

Immunogen

Osteoclasts from osteoclastomas

Reactivity Notes

Does not react with Bovine or Porcine or Rabbit.

Localization

Cell Surface

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Applications for Integrin alpha V/CD51 Antibody (23C6) [DyLight 350]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Integrin alpha V/CD51

Integrin alpha V chain interacts with the integrin beta 3 subunit/CD61 to form the alpha-V-beta-3 heterodimer/vitronectin receptor. It is expressed on endothelial cells, some activated leukocytes, NK cells, macrophages, neutrophils, and platelets. Integrin alpha V also forms heterodimers with the integrin beta 1, beta 5, beta 6, and beta 8 subunits. Alpha-V-beta-3 is an activation dependent receptor for platelet attachment and spreading on vitronectin and other matrix components.

Alternate Names

CD51, ITGAV, MSK8, Vitronectin Receptor alpha, VNRA

Gene Symbol

ITGAV

Additional Integrin alpha V/CD51 Products

Product Documents for Integrin alpha V/CD51 Antibody (23C6) [DyLight 350]

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Certificate of Analysis

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Product Specific Notices for Integrin alpha V/CD51 Antibody (23C6) [DyLight 350]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.