Chemical Name: 1-(4-Iodophenyl)-3-(2-adamantyl)guanidine
Biological ActivityIPAG is a potent σ-receptor antagonist.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Antagonism of N-MthD.-aspartate receptors by σ site ligands: potency, subtype-selectivity and mechanisms of inhibition.
Whittemore et al.
Radiosynthesis of σ receptor ligands for positron emission tomography: 11C- and 18F-labelled guanidines.
Wilson et al.
Citations for IPAG
The citations listed below are publications that use Tocris products. Selected citations for IPAG include:
2 Citations: Showing 1 - 2
Inhibition of tumor cell growth by Sigma1 ligand mediated translational repression.
Authors: Kim Et al.
Biochem Biophys Res Commun 2012;426:177
Antagonists show GTP-sensitive high-affinity binding to the sigma-1 receptor.
Authors: Brimson Et al.
Br J Pharmacol 2011;164:772
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