Catalog Number: 0544
Chemical Name: 1-(4-Iodophenyl)-3-(2-adamantyl)guanidine
Biological Activity
Potent σ-receptor antagonist.
Technical Data
  • M.Wt:
    395.29
  • Formula:
    C17H22IN3
  • Solubility:
    Soluble to 50 mM in ethanol and to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at RT
  • CAS No:
    193527-91-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Radiosynthesis of σ receptor ligands for positron emission tomography: 11C- and 18F-labelled guanidines.
    Wilson et al.
    J.Med.Chem., 1991;34:1867
  2. Antagonism of N-methyl-D-aspartate receptors by σ site ligands: potency, subtype-selectivity and mechanisms of inhibition.
    Whittemore et al.
    J.Pharmacol.Exp.Ther., 1997;282:326
Citations:

The citations listed below are publications that use Tocris products. Selected citations for IPAG include:

1 Citations: Showing 1 - 1

  1. Inhibition of tumor cell growth by Sigma1 ligand mediated translational repression.
    Authors: Kim Et al.
    Biochem Biophys Res Commun 2012;426:177

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