IQCB1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-47313

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

IQ motif containing B1. (Uniprot# Q15051)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IQCB1 Antibody - BSA Free

IQCB1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: IQCB1 Antibody - BSA Free [NBP3-47313] -

Immunocytochemistry/ Immunofluorescence: IQCB1 Antibody - BSA Free [NBP3-47313] - IF Result of anti-NPHP5 (IQCB1

Applications for IQCB1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:10-1:100

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: IQCB1

CEP290 activates ATF4 mediated transcription and is required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes. CEP290 is ubiquitously expressed; strongly in placenta and weakly in brain. There are two named isoforms. Defects in CEP290 are a cause of Joubert syndrome type 5 (JBTS5) [MIM:610188], Senior-Loken syndrome type 6 (SLSN6) [MIM:610189], Leber congenital amaurosis type 10 (LCA10) [MIM:611755] and Meckel syndrome type 4 (MKS4) [MIM:611134]. Antibodies against CEP290 are present in sera from patients with cutaneous T cell lymphomas, but not in the healthy control population.

Alternate Names

IQ calmodulin-binding motif containing 1, IQ motif containing B1, KIAA0036nephrocystin 5, Nephrocystin-5, NPHP5IQ calmodulin-binding motif-containing protein 1, p53 and DNA damage-regulated IQ motif protein, PIQ, SLSN5

Gene Symbol

IQCB1

Additional IQCB1 Products

Product Documents for IQCB1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for IQCB1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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