JAM-A Antibody (OTI3H3)

Name: JAM-A Antibody (OTI3H3)
Brand: Novus Biologicals
SKU: NBP2-45560
Price: 459 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-45560

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunocytochemistry/ Immunofluorescence

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG_2B Clone # OTI3H3

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Product Specifications

Immunogen

Full length human recombinant protein of human F11R(NP_653087) produced in HEK293T cell.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2B

Theoretical MW

29.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for JAM-A Antibody (OTI3H3)

Western Blot: JAM-A Antibody (OTI3H3) [NBP2-45560]

Western Blot: JAM-A Antibody (OTI3H3) [NBP2-45560] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY JAM-A.

Immunohistochemistry: JAM-A Antibody (OTI3H3) [NBP2-45560]

Immunohistochemistry: JAM-A Antibody (OTI3H3) [NBP2-45560] - Analysis of Carcinoma of Human lung tissue.(Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Immunohistochemistry: JAM-A Antibody (OTI3H3) [NBP2-45560]

Immunohistochemistry: JAM-A Antibody (OTI3H3) [NBP2-45560] - Analysis of Human Kidney tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Immunofluorescence: JAM-A Antibody (OTI3H3) [NBP2-45560]

Immunofluorescence: JAM-A Antibody (OTI3H3) [NBP2-45560] - Analysis of COS7 cells transiently transfected by pCMV6-ENTRY JAM-A.

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Applications for JAM-A Antibody (OTI3H3)

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry

1:150

Western Blot

1:4000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: JAM-A

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

Long Name

Junctional Adhesion Molecule A

Alternate Names

CD321, F11R, JAMA, PAM-1

Gene Symbol

F11R

Additional JAM-A Products

Product Documents for JAM-A Antibody (OTI3H3)

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Certificate of Analysis

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Product Specific Notices for JAM-A Antibody (OTI3H3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.