Chemical Name:4-[3-[4-[Piperidinyl]but-1-ynyl]benzyl]morpholine dihydrochloride
Biological Activity Histamine H3 receptor antagonist (pKi values are 8.15 and 8.93 for rat and human H3 receptors respectively). Increases extracellular norepinephrine and acetylcholine levels in rat frontal cortex but does not stimulate dopamine release. Brain penetrant.
Soluble to 100 mM in water and to 25 mM in ethanol
Desiccate at RT
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