Kv7.3 Antibody

Novus Biologicals | Catalog # NBP2-80515

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit
View all Kv7.3 Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide from amino acid region 60-120 of mouse Kv7.3 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in human and rat.

Clonality

Polyclonal

Host

Rabbit

Applications for Kv7.3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:2000

Immunohistochemistry-Paraffin

1:200 - 1:2000

Western Blot

1:200 - 1:2000

Formulation, Preparation, and Storage

Purification

Unpurified

Reconstitution

Reconstitute in 0.1 ml of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability.

Formulation

Lyophilized from whole serum

Preservative

No Preservative

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Kv7.3

KCNQ3 is a gene that codes for a protein with two isoforms, measuring 872 and 752 amino acids in length, with weights of approximately 97 and 85 kDa respectively. KCNQ3 is thought to be important in the regulation of neuronal excitability. Current studies are being done one several diseases and disorders linked to this gene including convulsions, myokymia with neonatal epilepsy, juvenile myoclonic epilepsy, generalized epilepsy, benign neonatal seizures, neuronitis, migraine, pharyngitis, and ataxia. KCNQ3 has also been shown to have interactions with CALM1, CALM2, CALM3, KCNQ4, and KCNQ2 in pathways such as the synaptic transmission-ion currents, L1CAM interactions, potassium channels, and celecoxib pathways.

Long Name

Potassium voltage-gated channel subfamily KQT member 3

Alternate Names

KCNQ3, KQT-like 3

Gene Symbol

KCNQ3

Additional Kv7.3 Products

Product Documents for Kv7.3 Antibody

Certificate of Analysis

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Product Specific Notices for Kv7.3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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