10 results for "Kv7.3" in Products
Kv7.3 Products
KCNQ3 is a gene that codes for a protein with two isoforms, measuring 872 and 752 amino acids in length, with weights of approximately 97 and 85 kDa respectively. KCNQ3 is thought to be important in the regulation of neuronal excitability. Current studies are being done one several diseases and disorders linked to this gene including convulsions, myokymia with neonatal epilepsy, juvenile myoclonic epilepsy, generalized epilepsy, benign neonatal seizures, neuronitis, migraine, pharyngitis, and ataxia. KCNQ3 has also been shown to have interactions with CALM1, CALM2, CALM3, KCNQ4, and KCNQ2 in pathways such as the synaptic transmission-ion currents, L1CAM interactions, potassium channels, and celecoxib pathways.
KV7 (KCNQ) channel blocker
| Alternate Names: | DuP 996 |
| Chemical Name: | 1,3-Dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-2H-indol-2-one dihydrochloride |
| Purity: | ≥98% |
Potassium channel modulator; exerts subtype-specific effects
| Chemical Name: | (3S)-3-(5-Chloro-2-methoxyphenyl)-3-fluoro-1,3-dihydro-6-(trifluoromethyl)-2H-Indol-2-one |
| Purity: | ≥98% |
Kv7 channel opener
| Chemical Name: | 5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one |
| Purity: | ≥98% |
| Reactivity: | Mouse, Hamster |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Kv7.3 Antibody [NBP1-74102]](https://resources.rndsystems.com/images/products/Kv7.3-Antibody-Western-Blot-NBP1-74102-img0004.jpg "Western Blot: Kv7.3 Antibody [NBP1-74102]")
KV7 channel activator; also GABAA modulator and indirect NMDA antagonist
| Alternate Names: | D 9998 |
| Chemical Name: | N-[2-Amino-6-[[4-fluorophenyl)methyl]amino]-3-pyridinyl]carbamic acid ethyl ester maleate |
| Purity: | ≥98% |
KV7.2/7.3 activator; displays anticonvulsant properties
| Chemical Name: | 4-Chloro-N-(6-chloro-3-pyridinyl)benzamide |
| Purity: | ≥98% |
KV7.2/KV7.3 channel opener
| Chemical Name: | N-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide |
| Purity: | ≥99% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat, Porcine |
| Details: | Goat IgG Polyclonal |
| Applications: | ELISA |
| Reactivity: | Human |
| Applications: | WB |
![Western Blot: Kv7.3 Overexpression Lysate [NBL1-12199]](https://resources.rndsystems.com/images/products/KCNQ3-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-12199-img0002.jpg "Western Blot: Kv7.3 Overexpression Lysate [NBL1-12199]")