Catalog Number: 0781
Chemical Name: 2-[5-[3-(4-Methylsulfonylamino)benzyl-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethanamine
Biological Activity
Selective and extremely potent 5-HT1D receptor agonist.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
  • Storage:
    Desiccate at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold with the permission of Merck Sharp and Dohme Ltd.
Background References
  1. L-694,247: a potent 5-HT1D receptor agonist.
    Beer et al.
    Br.J.Pharmacol., 1993;110:1196
  2. Evidence for presynaptic location of inhibitory 5-HT1Dβ -like autoreceptors in the guinea-pig brain cortex.
    Buhlen et al.
    Naunyn Schmiedebergs Arch.Pharmacol., 1996;353:281
  3. [3H]L-694,247 labels the 5-HT1Dβ receptor in pig caudate membranes.
    Heald et al.
    Eur.J.Pharmacol., 1994;264:213
  4. Synthesis and serotonergic activity of 5-(oxadiazoyl)tryptamines: potent agonists of 5-HT1D receptors.
    Street et al.
    J.Med.Chem., 1993;36:1529

The citations listed below are publications that use Tocris products. Selected citations for L-694,247 include:

1 Citations: Showing 1 - 1

  1. Molecular cloning, pharmacological properties and tissue distribution of the porcine 5-HT(1B) receptor.
    Authors: Bhalla Et al.
    Br J Pharmacol 2001;133:891

Have you used L-694,247?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details


Contact Information


Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

or select another batch: 


Customer Information