Potent and highly selective prostanoid EP3
receptor antagonist (Ki
values are 0.3, 916, > 5000 and > 5000 nM at EP3
respectively). Attenuates sulprostone-induced inhibition of EFS-evoked twitch and contractile responses in vivo
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Structure-activity relationships of cinnamic acylsulfonamide analogues on human EP3 prostanoid receptor.
Juteau et al.
E-ring 8-isoprostanes inhibit ACh release from parasympathetic nerves innervating guinea-pig trachea through agonism of prostanoid receptors of the EP3-subtype.
Clarke et al.
Activation of prostaglandin EP receptors by lubiprostone in rat and human stomach and colon.
Bassil et al.
The citations listed below are publications that use Tocris products. Selected citations for L-798,106 include:
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