L-798,106

Tocris Bioscience | Catalog # 3342

Potent and highly selective EP3 antagonist
Tocris Bioscience

Key Product Details

Description

Potent and highly selective EP3 antagonist
View all Prostanoid Receptor Antagonists »

Product Description

L-798,106 is a potent and highly selective prostanoid EP3 receptor antagonist (Ki values are 0.3, 916, > 5000 and > 5000 nM at EP3, EP4, EP1 and EP2 respectively). Attenuates sulprostone-induced inhibition of EFS-evoked twitch and contractile responses in vivo.

Product Specifications for L-798,106

Molecular Weight

536.44

Formula

C27H22BrNO4S

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide

CAS Number

244101-02-8

PubChem ID

15551229

InChI Key

ODTKFNUPVBULRJ-NTCAYCPXSA-N

SMILES

O=C(NS(C4=C(OC)C=CC(Br)=C4)(=O)=O)/C=C/C1=CC=CC=C1CC3=CC2=CC=CC=C2C=C3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 53.64 100

Preparing Stock Solutions for L-798,106

The following data is based on the product molecular weight 536.44.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.86 mL 9.32 mL 18.64 mL
5 mM 0.37 mL 1.86 mL 3.73 mL
10 mM 0.19 mL 0.93 mL 1.86 mL
50 mM 0.04 mL 0.19 mL 0.37 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 41 publications citing the usage of this product.

Product Documents for L-798,106

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for L-798,106

For research use only

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  • L-798,106
    Name: Melanie Ikeh
    Verified Customer | Posted 05/31/2017
    in vivo survival assay

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