L-798,106

  ( 5 citations ) ( 1 Review )    
Product Datasheet
Catalog Number:3342
Chemical Name:N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide
Product Details
Citations (5)
Supplemental Products
Reviews
Biological Activity
Potent and highly selective prostanoid EP3 receptor antagonist (Ki values are 0.3, 916, > 5000 and > 5000 nM at EP3, EP4, EP1 and EP2 respectively). Attenuates sulprostone-induced inhibition of EFS-evoked twitch and contractile responses in vivo.
Technical Data
  • M.Wt:
    536.44
  • Formula:
    C27H22BrNO4S
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    244101-02-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for L-798,106 include:

5 Citations: Showing 1 - 5
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  1. Prostaglandin receptor EP3 regulates cell proliferation and migration with impact on survival of endometrial cancer patients.
    Authors: Zhu
    Oncotarget  2018;9(1):982
  2. Exposure to 50 Hz magnetic field modulates GABAA currents in cerebellar granule neurons through an EP receptor-mediated PKC pathway.
    Authors: Yang Et al.
    J Cell Mol Med  2015;19:2413
  3. Effects of lipoic acid on lipolysis in 3T3-L1 adipocytes.
    Authors: Fernández-Galilea Et al.
    J Lipid Res  2012;53:2296
  4. Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP3 receptors.
    Authors: Tunaru Et al.
    Cell Commun Signal  2012;109:9179
  5. Protection of protease-activated receptor 2 mediated vasodilatation against angiotensin II-induced vascular dysfunction in mice.
    Authors: Chia Et al.
    BMC Pharmacol  2011;11:10

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