Catalog Number: 0341
Chemical Name: L-(+)-2-Amino-6-phosphonohexanoic acid
Biological Activity
Selective agonist for 'quis'-sensitized site.
Technical Data
  • M.Wt:
    211.15
  • Formula:
    C6H14NO5P
  • Solubility:
    Soluble to 100 mM in 1eq. NaOH
  • Storage:
    Store at RT
  • CAS No:
    78944-89-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Type 4a metabotropic glutamate receptor: identification of new potent agonists and differentiation from the L-(+)-2-amino-4-phosphonobutanoic acid-sensitive receptor in the lateral perforant pathway in rats.
    Johansen et al.
    Mol.Pharmacol., 1995;48:140
  2. Synthesis of oxadiazolidinedione derivatives as quisqualic acid analogues and their evaluation at a quisqualate-sensitized site in the rat hippocampus.
    Venkatraman et al.
    J.Med.Chem., 1994;37:3939
  3. Utilization of the resolved L-isomer of 2-amino-6-phosphonohexanoic acid (L-AP6) as a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons.
    Schulte et al.
    Brain Res., 1994;649:203

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