Catalog Number: 0664
Chemical Name: NG-Nitro-L-arginine
Biological Activity
NO synthase inhibitor.
Technical Data
  • M.Wt:
    219.2
  • Formula:
    C6H13N5O4
  • Solubility:
    Soluble to 5 mM in water
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    2149-70-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Nitric oxide synthase: irreversible inhibition by L-NG-nitroarginine in brain in vitro and in vivo.
    Dwyer et al.
    Biochem.Biophys.Res.Commun., 1991;176:1136
  2. Nitric oxide synthases in mammals.
    Knowles et al.
    Biochem.J., 1994;298:249
Citations:

The citations listed below are publications that use Tocris products. Selected citations for L-NNA include:

5 Citations: Showing 1 - 5
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  1. Nitric oxide targets oligodendrocytes and promotes their morphological differentiation.
    Authors: Garthwaite Et al.
    J Neurosci 2015;63:383
  2. On the selectivity of neuronal NOS inhibitors.
    Authors: Pigott Et al.
    Br J Pharmacol 2013;168:1255
  3. NO-released zinc supports the simultaneous binding of Raf-1 and PKCγ cysteine-rich domains to HINT1 protein at the mu-opioid receptor.
    Authors: Rodríguez-Muñoz Et al.
    Antioxid Redox Signal 2011;14:2413
  4. Mu-opioid receptors transiently activate the Akt-nNOS pathway to produce sustained potentiation of PKC-mediated NMDAR-CaMKII signaling.
    Authors: Sánchez-Blázquez Et al.
    PLoS One 2010;5:e11278
  5. Effects of cannabinoid receptor-2 activation on accelerated gastrointestinal transit in lipopolysaccharide-treated rats.
    Authors: Mathison Et al.
    Br J Pharmacol 2004;142:1247
Average Rating: 5 (Based on 1 review)

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