Catalog Number: 0664
Chemical Name: NG-Nitro-L-arginine
Biological Activity
NO synthase inhibitor.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 5 mM in water
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Nitric oxide synthase: irreversible inhibition by L-NG-nitroarginine in brain in vitro and in vivo.
    Dwyer et al.
    Biochem.Biophys.Res.Commun., 1991;176:1136
  2. Nitric oxide synthases in mammals.
    Knowles et al.
    Biochem.J., 1994;298:249

The citations listed below are publications that use Tocris products. Selected citations for L-NNA include:

Showing Results 1 - 5 of 5

  1. Nitric oxide targets oligodendrocytes and promotes their morphological differentiation.
    Authors: Garthwaite Et al.
    J Neurosci
  2. On the selectivity of neuronal NOS inhibitors.
    Authors: Pigott Et al.
    Br J Pharmacol
  3. NO-released zinc supports the simultaneous binding of Raf-1 and PKCγ cysteine-rich domains to HINT1 protein at the mu-opioid receptor.
    Authors: Rodríguez-Muñoz Et al.
    Antioxid Redox Signal
  4. Mu-opioid receptors transiently activate the Akt-nNOS pathway to produce sustained potentiation of PKC-mediated NMDAR-CaMKII signaling.
    Authors: Sánchez-Blázquez Et al.
    PLoS One
  5. Effects of cannabinoid receptor-2 activation on accelerated gastrointestinal transit in lipopolysaccharide-treated rats.
    Authors: Mathison Et al.
    Br J Pharmacol
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