L803-mts

2256 has been discontinued. View all GSK-3 Inhibitors products.
  ( 1 citations )    
Product Datasheet
Catalog Number:2256
Chemical Name:
Product Details
Citations (1)
Reviews
Biological Activity
Selective peptide inhibitor of glycogen synthase kinase-3 (GSK-3). Produces antidepressive behavior in mice when administered in vivo. Shows no inhibition of PKC, PKB or cdc2 protein kinase. Exhibits insulin mimetic activity. Activates glycogen synthase activity 2.5-fold in HEK293 cells.
Technical Data
  • M.Wt:
    1464.64
  • Formula:
    C66H110N15O20P
  • Sequence:
    GKEAPPAPPQSP

    (Modifications: Gly-1 = Myr-Gly, Pro-12 = C-terminal amide, Ser-11 = pSer)

  • Solubility:
    Soluble to 1 mg/ml in 20% acetonitrile / water
  • Storage:
    Store at -20°C
  • CAS No:
    1043881-55-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold under licence from Tel Aviv University Future Technology LP.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for L803-mts include:

1 Citations: Showing 1 - 1

  1. Glycogen synthase kinase-3 controls IL-10 expression in CD4(+) effector T-cell subsets through epigenetic modification of the IL-10 promoter.
    Authors: Hill Et al.
    Int J Obes (Lond)  2015;45:1103

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