Laminin S/Laminin beta 2 Antibody (CL2976) - BSA Free

Novus Biologicals | Catalog # NBP2-42386

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Knockdown Validated

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL2976

Format

BSA Free
View all Laminin S Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed using a recombinant protein derived from P55268, with the exact immunogen sequence remaining proprietary.

Reactivity Notes

Expected to cross react based on sequence identity: Mouse (83%), Rat (82%).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Laminin S/Laminin beta 2 Antibody (CL2976) - BSA Free

Western Blot: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Western Blot: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Western Blot: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386] - Analysis in human lung tissue.
Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386] - Staining of human lymph node shows absence of immunoreactivity in lymphoid cells (negative control).
Western Blot: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Western Blot: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Western Blot: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386] - Analysis of purified human recombinant Laminin-421, Laminin-521, Laminin-332 and Laminin-111.
Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386] - Staining of human heart shows strong membranous immunoreactivity in cardiomyocytes.
Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386] - Staining of human colon shows strong positivity in basement membrane of glandular epithelium.
Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386] - Staining of human skeletal muscle shows strong membranous immunoreactivity in myocytes.
Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386] - Staining of human kidney shows strong positivity in renal glomeruli.
Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386] - Staining of human cortex shows strong immunoreactivity in endothelial cells.

Applications for Laminin S/Laminin beta 2 Antibody (CL2976) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:5000 - 1:10000

Immunohistochemistry-Paraffin

1:5000-1:1000

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Laminin S

The Laminins comprise a growing family of disulfide-linked heterotrimers consisting of three genetically distinct polypeptide chains, designated alpha, beta and gamma. A major component of the basal lamina, Laminins play a crucial role in providing a scaffolding upon which tissues are assembled and which serves as a physical barrier separating specialized tissues. During embryogenesis and early development, cells migrate along basement membranes, which are required for the polarization of cells. The beta-2 laminin chain plays a role in melanoma spread, promoting tumor migration along the abluminal surface of vessel, a phenomenon which has been termed extra-vascular migratory metastasis.

Long Name

Laminin, beta 2

Alternate Names

LAMB2, Laminin beta 2

Gene Symbol

LAMB2

UniProt

P55268 (Human)

Additional Laminin S Products

Product Documents for Laminin S/Laminin beta 2 Antibody (CL2976) - BSA Free

Certificate of Analysis

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Product Specific Notices for Laminin S/Laminin beta 2 Antibody (CL2976) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Extracellular Matrix Molecules

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Protocols

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FAQs

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