Laulimalide

Catalog # Availability Size / Price Qty
4007/10U
Cat.No. 4007 - Laulimalide | C30H42O7 | CAS No. 115268-43-4
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Description: Microtubule stabilzing agent
Alternative Names: Fijianolide B

Chemical Name: (1R,3S,7S,8S,10S,12S,15Z,18R)-12-[(1S,2E)-3-[(2S)-3,6-dihydro-4-methyl-2H-pyran-2-yl]-1-hydroxy-2-propen-1-yl]-7-hydroxy-3-methyl-5-methylene-9,13,22-trioxatricyclo[16.3.1.08,10]docosa-15,19-dien-14-one

Purity: ≥97%

Product Details
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Biological Activity

Microtubule stabilizing agent. Potent inhibitor of cellular proliferation in cancer cell lines (IC50 reported to be 3-30 nM, dependent on cell line used). Causes cells to arrest in the prometaphase of the cell cycle, prevents formation of bipolar spindle and increases kinetochore tension in preformed spindles.

Technical Data

M.Wt:
514.65
Formula:
C30H42O7
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥97%
Storage:
Store at -20°C
CAS No:
115268-43-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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