Potent and selective dopamine D1
receptor antagonist (Ki
values are 0.08 - 1.9 nM and 6 - 45 nM for D1
receptors respectively). Also displays moderate affinity for the 5-HT2A
= 20 nM). Active in vivo
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Dopamine/serotonin receptor ligands: Part IV : Synthesis and pharmacology of novel 3-benzazecines and 3-benzazonines as potential 5-HT2A and dopamine receptor ligands.
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