LE 300

Catalog # Availability Size / Price Qty
1674/10
LE 300 | CAS No. 274694-98-3 | Dopamine D1 and D5 Receptor Antagonists
1 Image
Description: Potent and selective D1 antagonist

Chemical Name: 6,7,8,9,14,15-Hexahydro-7-methyl-5H-indolo[3,2-f][3]benzazecine

Purity: ≥98%

Product Details
Citations (2)
Supplemental Products
Reviews

Biological Activity

Potent and selective dopamine D1 receptor antagonist (Ki values are 0.08 - 1.9 nM and 6 - 45 nM for D1 and D2 receptors respectively). Also displays moderate affinity for the 5-HT2A receptor (Ki = 20 nM). Active in vivo.

Technical Data

M.Wt:
290.41
Formula:
C20H22N2
Solubility:
Soluble to 50 mM in 1eq. HCl and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
274694-98-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citations for LE 300

The citations listed below are publications that use Tocris products. Selected citations for LE 300 include:

2 Citations: Showing 1 - 2

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

VersaClone cDNA Plasmids

Reviews for LE 300

There are currently no reviews for this product. Be the first to review LE 300 and earn rewards!

Have you used LE 300?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.