Catalog Number: 1461
Chemical Name: 1,2-Dihydro-4-hydroxy-N,N-dimethyl-2-oxo-N-phenyl-3-quinolinecarboxamide
Biological Activity
Immunomodulator with stimulatory and antitumor properties. Inhibits in vivo apoptosis of T cells and inhibits angiogenesis in rats in vivo.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in 1.1eq. NaOH
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. The antitumor effects of the quinoline-3-carboxamide linomide on Dunning R-3327 rat prostatic cancers.
    Ichikawa et al.
    Cancer Res., 1992;52:3022
  2. Linomide inhibits programmed cell death of peripheral T cells in vivo.
    Gonzalo et al.
    Eur.J.Immunol., 1994;24:48
  3. Antiangiogenic effects of the quinoline-3-carboxamide linomide.
    Vukanovic et al.
    Cancer Res., 1993;53:1833
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