Catalog Number: 4704
Chemical Name: 1-(4'-Methoxy[1,1-biphenyl]-2-yl)piperazine hydrochloride
Biological Activity
Ligand of the 5-HT7 receptor (Ki = 2.6 nM); exhibits agonist and antagonist activity. Displays selectivity over adrenergic α1 and 5-HT1A receptors (Ki values are 156 and 476 nM respectively).
Technical Data
  • M.Wt:
    304.81
  • Formula:
    C17H20N2O.HCl
  • Solubility:
    Soluble to 50 mM in water and to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Desiccate at RT
  • CAS No:
    1386928-34-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold under license from the University of Bari
Background References
  1. Investigations on the 1-(2-biphenyl)piperazine motif: identification of new potent and selective ligands for the serotonin7 (5-HT7) receptor with agonist or antagonist action in vitro or ex vivo.
    Lacivita et al.
    J.Med.Chem., 2012;55:6375

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