Catalog Number: 4881
Chemical Name: 5-Butyl-1H-pyrazole-3-carboxylic acid
Biological Activity
Partial agonist of hydroxycarboxylic acid receptor 2 (HCA2) (Ki = 0.55 μM). Thought to lower plasma very-low-density lipoprotein (VLDL)-triglyceride levels by affecting hepatic VLDL production in normolipidemic C57BL/6 mice.
Technical Data
  • M.Wt:
    168.19
  • Formula:
    C8H12N2O2
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98%
  • Storage:
    Store at +4°C
  • CAS No:
    92933-48-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Effects of pyrazole partial agonists on HCA2-mediated flushing and VLDL-triglyceride levels in mice.
    Li et al.
    Br.J.Pharmacol., 2012;167:818

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