Chemical Name: 5-Butyl-1H-pyrazole-3-carboxylic acid
Biological ActivityPartial agonist of hydroxycarboxylic acid receptor 2 (HCA2) (Ki = 0.55 μM). Thought to lower plasma very-low-density lipoprotein (VLDL)-triglyceride levels by affecting hepatic VLDL production in normolipidemic C57BL/6 mice.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Effects of pyrazole partial agonists on HCA2-mediated flushing and VLDL-triglyceride levels in mice.
Li et al.
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VersaClone cDNA Plasmids
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