Chemical Name: (2R*,4S*)-4-(1H-Tetrazol-5-ylmethyl)-2-piperidinecarboxylic acid
Biological ActivityCompetitive NMDA receptor antagonist (IC50 = 7 nM) that displays no affinity for AMPA or kainate receptors at a concentration of 10 μM. Inhibits NMDA-induced neuronal degeneration and protects from NMDA-induced convulsions in neonatal rats.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Pharmacological characterization of LY233053: a structurally novel tetrazole-substituted competitive N-MthD.-aspartic acid antagonist with a short duration of action.
Schoepp et al.
Efficacy of LY233053, a competitive glutamate antagonist, in experimental central nervous system ischemia.
Madden et al.
Delayed therapy of experimental ischemia with competitive N-MthD.-aspartate antagonists in rabbits.
Madden et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for LY 233053
There are currently no reviews for this product. Be the first to review LY 233053 and earn rewards!
Have you used LY 233053?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image