LY 311727

3627 has been discontinued. View all Phospholipase Inhibitors products.
  ( 1 citations )    
Product Datasheet
Catalog Number:3627
Chemical Name:[3-[[3-(2-Amino-2-oxoethyl)-2-ethyl-1-(phenylmethyl)-1H-indol-5-yl]oxy]propyl]-phosphonic acid
Product Details
Citations (1)
Reviews
Biological Activity
Selective secreted phospholipase A2 (sPLA2) inhibitor (IC50 values are <1 μM for group IIA and <50 μM for group V). Attenuates VEGF-mediated platelet-activating factor (PAF) synthesis in BAEC and HUVEC cells at a concentration of 100 μM.
Technical Data
  • M.Wt:
    430.43
  • Formula:
    C22H27N2O5P
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in 1eq. NaOH
  • Purity:
    >97
  • Storage:
    Store at +4°C
  • CAS No:
    164083-84-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
COA view current batch
or select another batch:
Citations:

The citations listed below are publications that use Tocris products. Selected citations for LY 311727 include:

1 Citations: Showing 1 - 1

  1. Evidence for distinct mechanisms of uptake and antitumor activity of secretory phospholipase A2 responsive liposome in prostate cancer.
    Authors: Mock Et al.
    Integr Biol (Camb)  2013;5:172

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Have you used LY 311727?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.
Contact Us to Order
reload

Feedback

Customer Information
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee