Macro H2A.2 Antibody (CL5263) - BSA Free

Novus Biologicals | Catalog # NBP2-61156

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL5263

Format

BSA Free
View all Macro H2A.2 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed using a synthetic peptide derived from Q9P0M6, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Macro H2A.2 Antibody (CL5263) - BSA Free

Immunocytochemistry/ Immunofluorescence: Macro H2A.2 Antibody (CL5263) [NBP2-61156]

Immunocytochemistry/ Immunofluorescence: Macro H2A.2 Antibody (CL5263) [NBP2-61156]

Immunocytochemistry/Immunofluorescence: Macro H2A.2 Antibody (CL5263) [NBP2-61156] - Staining of PC-3 cells using the Anti-H2AFY2 monoclonal antibody, showing specific staining in the nucleoplasm and nuclear membrane in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available).
Immunohistochemistry: Macro H2A.2 Antibody (CL5263) [NBP2-61156]

Immunohistochemistry: Macro H2A.2 Antibody (CL5263) [NBP2-61156]

Immunohistochemistry: Macro H2A.2 Antibody (CL5263) [NBP2-61156] - Immunohistochemical staining of human kidney shows strong nuclear positivity in cells in renal glomeruli and a subset of renal tubules.
Immunohistochemistry: Macro H2A.2 Antibody (CL5263) [NBP2-61156]

Immunohistochemistry: Macro H2A.2 Antibody (CL5263) [NBP2-61156]

Immunohistochemistry: Macro H2A.2 Antibody (CL5263) [NBP2-61156] - Immunohistochemical staining of human testis shows strong nuclear immunoreactivity in a subset of cells in seminiferous tubules.
Immunohistochemistry: Macro H2A.2 Antibody (CL5263) [NBP2-61156]

Immunohistochemistry: Macro H2A.2 Antibody (CL5263) [NBP2-61156]

Immunohistochemistry: Macro H2A.2 Antibody (CL5263) [NBP2-61156] - Immunohistochemical staining of human fallopian tube shows strong nuclear immunoreactivity in glandular cells and moderate positivity in stromal cells.
Immunohistochemistry: Macro H2A.2 Antibody (CL5263) [NBP2-61156]

Immunohistochemistry: Macro H2A.2 Antibody (CL5263) [NBP2-61156]

Immunohistochemistry: Macro H2A.2 Antibody (CL5263) [NBP2-61156] - Immunohistochemical staining of human cerebral cortex shows moderate to strong nuclear immunoreactivity in neuronal and glial cells.

Applications for Macro H2A.2 Antibody (CL5263) - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

2-10 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. For ICC/IF, PFA/Triton X-100 is recommended for fixation/permeabilization.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Macro H2A.2

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation

Alternate Names

core histone macro-H2A.2, core histone macroH2A2.2, H2A histone family, member Y2, Histone macroH2A2, MACROH2A2, mH2A2

Gene Symbol

MACROH2A2

Additional Macro H2A.2 Products

Product Documents for Macro H2A.2 Antibody (CL5263) - BSA Free

Certificate of Analysis

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Product Specific Notices for Macro H2A.2 Antibody (CL5263) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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