MATN3 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-77017

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Chicken (90%). Backed by our 100% Guarantee.

Applications

Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

Antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human MATN3. The immunogen is located within amino acids 400 - 450 of MATN3. Amino Acid Squence: YPGYTLNEDKKT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MATN3 Antibody - BSA Free

Western Blot: MATN3 AntibodyBSA Free [NBP1-77017]

Western Blot: MATN3 AntibodyBSA Free [NBP1-77017]

Western Blot: MATN3 Antibody [NBP1-77017] - 3T3 cell lysate with MATN3 antibody at (A) 1 and (B) 2 ug/mL.
MATN3 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: MATN3 Antibody - BSA Free [NBP1-77017] -

Immunocytochemistry/ Immunofluorescence: MATN3 Antibody - BSA Free [NBP1-77017] - Immunocytochemistry of MATN3 in 3T3 cells with MATN3 antibody at 5 ug/mL.

Applications for MATN3 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Matrilin-3

Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN3 is composed of a single N-terminal von Willebrand Factor A (vWFA) domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain whereas MATN1 is composed of two vWFA domains separated by one EGF-like domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that aberrant expression and processing of MATN3 are hallmarks of conventional cartilaginous neoplasms.

Alternate Names

EDM5, HOA, Matrilin3, NDUFC2

Gene Symbol

MATN3

Additional Matrilin-3 Products

Product Documents for MATN3 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for MATN3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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