Catalog Number: 4443
Chemical Name: (±)-2-Methylamino-1-(4-methylphenyl)propan-1-one hydrochloride
Biological Activity
Inhibits striatal dopamine uptake and hippocampal 5-HT uptake in synaptosomes (IC50 values are 467 and 558 nM respectively). Administration causes a decrease in dopamine and 5-HT transporter function. Synthetic CNS stimulant; brain penetrant.
Technical Data
  • M.Wt:
    213.7
  • Formula:
    C11H15NO.HCl
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    1189726-22-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. 4-methylmethcathinone (mephedrone): neuropharmacological effects of a designer stimulant of abuse.
    Hadlock et al.
    J.Pharmacol.Exp.Ther., 2011;339:530

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