Inhibits striatal dopamine uptake and hippocampal 5-HT uptake in synaptosomes (IC50
values are 467 and 558 nM respectively). Administration causes a decrease in dopamine and 5-HT transporter function. Synthetic CNS stimulant; brain penetrant.
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All Tocris products are intended for laboratory research use only.
4-methylmethcathinone (mephedrone): neuropharmacological effects of a designer stimulant of abuse.
Hadlock et al.