Extremely selective histamine H3
receptor agonist (pKi
values are 9.0, 5.7, < 5.0 and < 5.0 for hH3
receptors respectively). Potently inhibits EFS-evoked contractions of guinea pig ileum (pD2
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N-substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist.
Kitbunnadaj et al.